Total synthesis of (-)-platensimycin, a novel antibacterial agent.
about
Harnessing nature's insight: design of aspartyl protease inhibitors from treatment of drug-resistant HIV to Alzheimer's disease.Capturing the essence of organic synthesis: from bioactive natural products to designed molecules in today's medicine.Discovery of novel FabF ligands inspired by platensimycin by integrating structure-based design with diversity-oriented synthetic accessibility.Constructing molecular complexity and diversity: total synthesis of natural products of biological and medicinal importance.A symmetry-based concise formal synthesis of platencin, a novel lead against "superbugs".Total synthesis of platensimycin and related natural productsSynthesis and antibacterial properties of (-)-nor-platencin.Platensimycin and its relatives: a recent story in the struggle to develop new naturally derived antibiotics.Inhibitors of fatty acid synthesis in prokaryotes and eukaryotes as anti-infective, anticancer and anti-obesity drugs.The asymmetric hetero-Diels-Alder reaction in the syntheses of biologically relevant compounds.Total synthesis of natural products using hypervalent iodine reagents.Navigating the Chiral Pool in the Total Synthesis of Complex Terpene Natural Products.A brief history of antibiotics and select advances in their synthesis.A concise ring-expansion route to the compact core of platensimycin.Total synthesis of (-)-platensimycin by advancing oxocarbenium- and iminium-mediated catalytic methods.A highly efficient Friedel-Crafts reaction of 3-hydroxyoxindoles and aromatic compounds to 3,3-diaryl and 3-alkyl-3-aryloxindoles catalyzed by Hg(ClO4)2·3H2O.Dialkylamino-2,4-dihydroxybenzoic acids as easily synthesized analogues of platensimycin and platencin with comparable antibacterial properties.A radical cyclization approach to the formal total syntheses of platencin.
P2860
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P2860
Total synthesis of (-)-platensimycin, a novel antibacterial agent.
description
2009 nî lūn-bûn
@nan
2009 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
name
Total synthesis of (-)-platensimycin, a novel antibacterial agent.
@ast
Total synthesis of (-)-platensimycin, a novel antibacterial agent.
@en
type
label
Total synthesis of (-)-platensimycin, a novel antibacterial agent.
@ast
Total synthesis of (-)-platensimycin, a novel antibacterial agent.
@en
prefLabel
Total synthesis of (-)-platensimycin, a novel antibacterial agent.
@ast
Total synthesis of (-)-platensimycin, a novel antibacterial agent.
@en
P2860
P356
P1476
Total synthesis of (-)-platensimycin, a novel antibacterial agent.
@en
P2093
P2860
P304
P356
10.1021/JO802261F
P407
P577
2009-02-01T00:00:00Z