New insights into the regulation of T cells by gamma(c) family cytokines - Test2 - elhamkhani - TriplyDB

New insights into the regulation of T cells by gamma(c) family cytokines

New insights into the regulation of T cells by gamma(c) family cytokines

http://www.wikidata.org/entity/Q33623326

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Identification of STAT5A and STAT5B target genes in human T cells C17 prevents inflammatory arthritis and associated joint destruction in mice Evolutionary divergence and functions of the human interleukin (IL) gene family Mechanistic and structural insight into the functional dichotomy between IL-2 and IL-15 Interleukin-2 receptor signaling: at the interface between tolerance and immunity IL-2 family cytokines: new insights into the complex roles of IL-2 as a broad regulator of T helper cell differentiation Exploiting a natural conformational switch to engineer an interleukin-2 'superkine'Structural basis of receptor sharing by interleukin 17 cytokines Breaking Free of Control: How Conventional T Cells Overcome Regulatory T Cell Suppression.Mathematics in modern immunology IL-21 Signaling in Immunity Chimeric Antigen Receptors Modified T-Cells for Cancer Therapy Type I/II cytokines, JAKs, and new strategies for treating autoimmune diseases Animal Models for Alopecia Areata: What and Where?Natural killer cell responses during viral infections: flexibility and conditioning of innate immunity by experience Insights into cytokine-receptor interactions from cytokine engineering Can immunotherapy be useful as a "functional cure" for infection with Human Immunodeficiency Virus-1?Humanized mice: novel model for studying mechanisms of human immune-based therapies Intratibial injection of human multiple myeloma cells in NOD/SCID IL-2Rγ(null) mice mimics human myeloma and serves as a valuable tool for the development of anticancer strategies Trypanosoma cruzi Experimental Infection Impacts on the Thymic Regulatory T Cell Compartment Interleukin-21 accelerates thymic recovery from glucocorticoïd-induced atrophy Targeting the binding interface on a shared receptor subunit of a cytokine family enables the inhibition of multiple member cytokines with selectable target spectrum.Co-administration of IL-1+IL-6+TNF-α with Mycobacterium tuberculosis infected macrophages vaccine induces better protective T cell memory than BCG Genetics of SCID Crystal Structure of Interleukin-21 Receptor (IL-21R) Bound to IL-21 Reveals That Sugar Chain Interacting with WSXWS Motif Is Integral Part of IL-21R Structural reorganization of the interleukin-7 signaling complex Instructive roles for cytokine-receptor binding parameters in determining signaling and functional potency Emerging Therapies for Rheumatoid Arthritis IL7Rα expression and upregulation by IFNβ in dendritic cell subsets is haplotype-dependent Time-Dependent Regulation of IL-2R α-Chain (CD25) Expression by TCR Signal Strength and IL-2-Induced STAT5 Signaling in Activated Human Blood T Lymphocytes Dual anti-OX40/IL-2 therapy augments tumor immunotherapy via IL-2R-mediated regulation of OX40 expression Safety and immunogenicity of an HIV-1 gag DNA vaccine with or without IL-12 and/or IL-15 plasmid cytokine adjuvant in healthy, HIV-1 uninfected adults Essential biphasic role for JAK3 catalytic activity in IL-2 receptor signaling The effects of IL2Rgamma knockout on depression and contextual memory Dynamic membrane remodeling at invadopodia differentiates invadopodia from podosomes Clinical impact of immune microenvironment in stage I lung adenocarcinoma: tumor interleukin-12 receptor β2 (IL-12Rβ2), IL-7R, and stromal FoxP3/CD3 ratio are independent predictors of recurrence.Selective Janus associated kinase 1 inhibition as a therapeutic target in myelofibrosis.Comparative and kinetic analysis of viral shedding and immunological responses in MERS patients representing a broad spectrum of disease severity NSC114792, a novel small molecule identified through structure-based computational database screening, selectively inhibits JAK3 Human allograft rejection in humanized mice: a historical perspective

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New insights into the regulation of T cells by gamma(c) family cytokines

http://www.wikidata.org/entity/Q33623326

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2009 nî lūn-bûn

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2009 թուականի Յուլիսին հրատարակուած գիտական յօդուած

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2009 թվականի հուլիսին հրատարակված գիտական հոդված

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2009年の論文

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2009年学术文章

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2009年学术文章

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2009年学术文章

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2009年学术文章

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2009年学术文章

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2009年學術文章

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New insights into the regulation of T cells by gamma(c) family cytokines

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New insights into the regulation of T cells by gamma(c) family cytokines

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New insights into the regulation of T cells by gamma(c) family cytokines

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New insights into the regulation of T cells by gamma(c) family cytokines

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New insights into the regulation of T cells by gamma(c) family cytokines

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New insights into the regulation of T cells by gamma(c) family cytokines

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Nature Reviews Immunology

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New insights into the regulation of T cells by gamma(c) family cytokines

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Rosanne Spolski

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Warren J Leonard

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Yrina Rochman

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P2860

Defective IL7R expression in T(-)B(+)NK(+) severe combined immunodeficiency

IL-21 up-regulates the expression of genes associated with innate immunity and Th1 response

Cloning of human Stat5B. Reconstitution of interleukin-2-induced Stat5A and Stat5B DNA binding activity in COS-7 cells

IL-7 administration to humans leads to expansion of CD8+ and CD4+ cells but a relative decrease of CD4+ T-regulatory cells

Generation of T follicular helper cells is mediated by interleukin-21 but independent of T helper 1, 2, or 17 cell lineages

Specific microbiota direct the differentiation of IL-17-producing T-helper cells in the mucosa of the small intestine

Interleukin 21 is a T helper (Th) cell 2 cytokine that specifically inhibits the differentiation of naive Th cells into interferon gamma-producing Th1 cells

Antiviral CD4+ memory T cells are IL-15 dependent

Interleukin-21 inhibits dendritic cell activation and maturation

IL-15 is expressed by dendritic cells in response to type I IFN, double-stranded RNA, or lipopolysaccharide and promotes dendritic cell activation

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10.1038/NRI2580

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