about
A peptide derived from G0/G1 switch gene 2 acts as noncompetitive inhibitor of adipose triglyceride lipase.G0S2 modulates homeostatic proliferation of naïve CD8⁺ T cells and inhibits oxidative phosphorylation in mitochondriaRegulation of G0/G1 Switch Gene 2 (G0S2) Protein Ubiquitination and Stability by Triglyceride Accumulation and ATGL InteractionG0S2 Suppresses Oncogenic Transformation by Repressing a MYC-Regulated Transcriptional Program.Deletion of the gene encoding G0/G 1 switch protein 2 (G0s2) alleviates high-fat-diet-induced weight gain and insulin resistance, and promotes browning of white adipose tissue in mice.Upregulation of Pnpla2 and Abhd5 and downregulation of G0s2 gene expression in mesenteric white adipose tissue as a potential reason for elevated concentration of circulating NEFA after removal of retroperitoneal, epididymal, and inguinal adipose tiAdipocyte-specific Hypoxia-inducible gene 2 promotes fat deposition and diet-induced insulin resistance.Human Intervention Study to Assess the Effects of Supplementation with Olive Leaf Extract on Peripheral Blood Mononuclear Cell Gene Expression.Liver X receptor α mediates hepatic triglyceride accumulation through upregulation of G0/G1 Switch Gene 2 expression.Inhibition of adipose triglyceride lipase (ATGL) by the putative tumor suppressor G0S2 or a small molecule inhibitor attenuates the growth of cancer cells.G0S2: A small giant controller of lipolysis and adipose-liver fatty acid flux.G0S2 represses PI3K/mTOR signaling and increases sensitivity to PI3K/mTOR pathway inhibitors in breast cancer.
P2860
Q34552596-FDA8B71A-087D-4EAF-9B5B-4F0C801660A3Q35935293-3C3A7928-F855-48B4-B355-D5F2812FB630Q36036132-D04B126C-494B-4273-9D00-2C725C4D62A0Q36642613-BAA8AAF7-9CDC-495A-B62E-31D568CB43F6Q37210599-3A3EC83A-C9BF-4998-82D6-3BCE8532603AQ37321929-1FA41DA5-6254-4CD6-8B1A-DA56D9E1D3AAQ37439985-5D89C8A9-C007-4271-B31C-E90E15616B13Q37534624-46730C48-398E-4D80-9862-A769D7824594Q37646873-6C582BA9-BC9E-4E9B-8D36-60D9992B61DCQ38839895-EF3F0873-876E-4756-BBD5-5BF99C25AA0CQ39395189-B050DBCB-99A7-4D6E-977E-945743461147Q42515055-2DBFA53C-31D6-418A-8C54-A96110056C13
P2860
description
2014 nî lūn-bûn
@nan
2014 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2014 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2014年の論文
@ja
2014年論文
@yue
2014年論文
@zh-hant
2014年論文
@zh-hk
2014年論文
@zh-mo
2014年論文
@zh-tw
2014年论文
@wuu
name
Mice lacking G0S2 are lean and cold-tolerant.
@ast
Mice lacking G0S2 are lean and cold-tolerant.
@en
type
label
Mice lacking G0S2 are lean and cold-tolerant.
@ast
Mice lacking G0S2 are lean and cold-tolerant.
@en
prefLabel
Mice lacking G0S2 are lean and cold-tolerant.
@ast
Mice lacking G0S2 are lean and cold-tolerant.
@en
P2093
P2860
P921
P356
P1476
Mice lacking G0S2 are lean and cold-tolerant.
@en
P2093
Alexandra G N Lopez-Aguiar
David Sekula
Ethan Dmitrovsky
Eugene E Nattie
Sarah Freemantle
P2860
P304
P356
10.4161/CBT.28251
P577
2014-02-20T00:00:00Z