Nuclear localization signal deletion mutants of lamin A and progerin reveal insights into lamin A processing and emerin targeting
about
The expression of Lamin A mutant R321X leads to endoplasmic reticulum stress with aberrant Ca2+ handling.Comparing lamin proteins post-translational relative stability using a 2A peptide-based system reveals elevated resistance of progerin to cellular degradation.Lamins at the crossroads of mechanosignalingMG132-induced progerin clearance is mediated by autophagy activation and splicing regulation.Protein sequestration at the nuclear periphery as a potential regulatory mechanism in premature aging.Lamin A and microtubules collaborate to maintain nuclear morphology.Emerin modulates spatial organization of chromosome territories in cells on softer matrices.Lamin mutation location predicts cardiac phenotype severity: combined analysis of the published literature
P2860
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P2860
Nuclear localization signal deletion mutants of lamin A and progerin reveal insights into lamin A processing and emerin targeting
description
2014 nî lūn-bûn
@nan
2014 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2014 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2014年の論文
@ja
2014年論文
@yue
2014年論文
@zh-hant
2014年論文
@zh-hk
2014年論文
@zh-mo
2014年論文
@zh-tw
2014年论文
@wuu
name
Nuclear localization signal de ...... rocessing and emerin targeting
@ast
Nuclear localization signal de ...... rocessing and emerin targeting
@en
type
label
Nuclear localization signal de ...... rocessing and emerin targeting
@ast
Nuclear localization signal de ...... rocessing and emerin targeting
@en
prefLabel
Nuclear localization signal de ...... rocessing and emerin targeting
@ast
Nuclear localization signal de ...... rocessing and emerin targeting
@en
P2093
P2860
P356
P1433
P1476
Nuclear localization signal de ...... rocessing and emerin targeting
@en
P2093
P2860
P356
10.4161/NUCL.28068
P577
2014-01-01T00:00:00Z