More than 1,001 problems with protein domain databases: transmembrane regions, signal peptides and the issue of sequence homology.
about
Epithelial sodium transport and its control by aldosterone: the story of our internal environment revisitedDe-DUFing the DUFs: Deciphering distant evolutionary relationships of Domains of Unknown Function using sensitive homology detection methods.Beyond the E-Value: Stratified Statistics for Protein Domain Prediction.Comprehensive analysis of the numbers, lengths and amino acid compositions of transmembrane helices in prokaryotic, eukaryotic and viral integral membrane proteins of high-resolution structure.Filtering "genic" open reading frames from genomic DNA samples for advanced annotation.A horizontal alignment tool for numerical trend discovery in sequence data: application to protein hydropathy.xHMMER3x2: Utilizing HMMER3's speed and HMMER2's sensitivity and specificity in the glocal alignment mode for improved large-scale protein domain annotation.On the necessity of dissecting sequence similarity scores into segment-specific contributions for inferring protein homology, function prediction and annotation.The Janus-faced E-values of HMMER2: extreme value distribution or logistic function?A comprehensive benchmark study of multiple sequence alignment methods: current challenges and future perspectives.Transamidase subunit GAA1/GPAA1 is a M28 family metallo-peptide-synthetase that catalyzes the peptide bond formation between the substrate protein's omega-site and the GPI lipid anchor's phosphoethanolamine.HGTector: an automated method facilitating genome-wide discovery of putative horizontal gene transfersThe PRINTS database: a fine-grained protein sequence annotation and analysis resource--its status in 2012Quality of computationally inferred gene ontology annotations.Dynamics of domain coverage of the protein sequence universe.Not all transmembrane helices are born equal: Towards the extension of the sequence homology concept to membrane proteins.Sequence-divergent chordopoxvirus homologs of the o3 protein maintain functional interactions with components of the vaccinia virus entry-fusion complex.dissectHMMER: a HMMER-based score dissection framework that statistically evaluates fold-critical sequence segments for domain fold similarity.A topology-based metric for measuring term similarity in the gene ontology.Transmembrane helix: simple or complex.3PFDB+: improved search protocol and update for the identification of representatives of protein sequence domain familiesComputational approaches to selecting and optimising targets for structural biology.Charged residues next to transmembrane regions revisited: "Positive-inside rule" is complemented by the "negative inside depletion/outside enrichment rule"An enhanced algorithm for multiple sequence alignment of protein sequences using genetic algorithm.Evolution and quantitative comparison of genome-wide protein domain distributions.The Remorin C-terminal Anchor was shaped by convergent evolution among membrane binding domainsA new repeat-masking method enables specific detection of homologous sequences.Camps 2.0: exploring the sequence and structure space of prokaryotic, eukaryotic, and viral membrane proteins.Evolution of the epithelial sodium channel and the sodium pump as limiting factors of aldosterone action on sodium transport.Bioinformatic characterization of the Anoctamin Superfamily of Ca2+-activated ion channels and lipid scramblases.
P2860
Q28083698-302D0EC2-6685-47F5-B41E-9D71DE4DC448Q28546880-6F08E4F0-04D9-460D-A51A-18DACD26E0B4Q30381459-2C0628AA-7E50-4BB3-8080-AD468B867BDDQ30398125-12F3EDFF-1A31-470B-B92A-D8E4288E0521Q30405569-343E8078-C20A-4940-BF42-13265AB46302Q30678483-C746E456-ECDD-4A14-922C-DC8F5C520DD1Q30830075-0D1D48EE-DBF7-4ADC-9445-3C9AB4809AB6Q33769219-41521165-200C-457F-B145-3E16312EC30FQ33822787-70791FE5-DB43-4779-B28E-10185B34BC11Q33869871-7D95EA6A-9046-4DEA-A8F6-47157763C706Q33953108-D105A004-4297-41E7-867B-44F20183E43EQ34135992-22CD32A9-CF40-4E97-B933-DE5253CD775EQ34268649-D9CEAFAD-2CF8-46A7-AC05-63D365D4F2CCQ34302143-A4BAD678-F3FB-4F32-AEE6-5BB1925E5CF4Q34479676-2CCF0CD6-1C09-4B95-8394-F6BFD0FF5EE8Q35554923-AFE2F47A-2AF6-4FFE-95B0-FABA964358C0Q35689728-54B79440-94D7-4438-BF72-C8F6680D3443Q35906254-56A81198-74F2-4806-874D-44E32A0FCFC4Q35990752-6C8C69BC-F147-485C-B608-4D2A4630DB73Q36088352-6C799582-E2EC-4C93-9DE7-F82BCA337A26Q37682199-8CB5DC81-9B5C-465A-88DA-D0C2033F24E9Q38332028-4B264482-38CC-4BE0-A1E7-D62572E4A8CFQ38664342-EAFFD93E-99EE-42FC-9163-85501070C56EQ39865959-900AFB2A-2738-4129-B619-4B8EEE3FD214Q41962436-2D95C8BE-467E-48CC-88F8-86933A0F4AA9Q42145472-ACFCBD8E-59D6-4207-9DBD-4512F4F048C5Q42635759-3277E67A-431A-42F2-81EE-4D6E5E510A98Q43553705-49448A61-9A55-4D1A-80E3-EA480BE386A1Q44091935-EB51942B-CA47-46C6-A85C-245B30BFB55EQ55050600-5A9D7A4A-45DE-4347-AB6F-878077188F36
P2860
More than 1,001 problems with protein domain databases: transmembrane regions, signal peptides and the issue of sequence homology.
description
2010 nî lūn-bûn
@nan
2010 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
More than 1,001 problems with ...... he issue of sequence homology.
@ast
More than 1,001 problems with ...... he issue of sequence homology.
@en
type
label
More than 1,001 problems with ...... he issue of sequence homology.
@ast
More than 1,001 problems with ...... he issue of sequence homology.
@en
prefLabel
More than 1,001 problems with ...... he issue of sequence homology.
@ast
More than 1,001 problems with ...... he issue of sequence homology.
@en
P2093
P2860
P1476
More than 1,001 problems with ...... he issue of sequence homology.
@en
P2093
Frank Eisenhaber
Sebastian Maurer-Stroh
Wing-Cheong Wong
P2860
P304
P356
10.1371/JOURNAL.PCBI.1000867
P577
2010-07-29T00:00:00Z