De novo mutations in schizophrenia implicate chromatin remodeling and support a genetic overlap with autism and intellectual disability
about
TRAPP Complexes in Secretion and AutophagyMutations and Modeling of the Chromatin Remodeler CHD8 Define an Emerging Autism EtiologyThe PsychENCODE projectToward a Deeper Understanding of the Genetics of Bipolar DisorderMolecular underpinnings of prefrontal cortex development in rodents provide insights into the etiology of neurodevelopmental disordersWnt signaling networks in autism spectrum disorder and intellectual disabilityThe contribution of de novo coding mutations to autism spectrum disorderMice with Shank3 Mutations Associated with ASD and Schizophrenia Display Both Shared and Distinct Defects.The Neurobiological Basis for Social Affiliation in Autism Spectrum Disorder and Schizophrenia.Loss of MeCP2 in the rat models regression, impaired sociability and transcriptional deficits of Rett syndrome.MEF2C regulates cortical inhibitory and excitatory synapses and behaviors relevant to neurodevelopmental disorders.Transcriptome analysis of microglia in a mouse model of Rett syndrome: differential expression of genes associated with microglia/macrophage activation and cellular stressMerging data from genetic and epigenetic approaches to better understand autistic spectrum disorder.Consensus paper of the WFSBP Task Force on Biological Markers: Criteria for biomarkers and endophenotypes of schizophrenia part II: Cognition, neuroimaging and genetics.Next-generation DNA sequencing identifies novel gene variants and pathways involved in specific language impairmentPaternal age and psychiatric disorders: A review.Exome sequencing for bipolar disorder points to roles of de novo loss-of-function and protein-altering mutations.Rare damaging variants in DNA repair and cell cycle pathways are associated with hippocampal and cognitive dysfunction: a combined genetic imaging study in first-episode treatment-naive patients with schizophrenia.Neuronal Migration and AUTS2 Syndrome.De novo non-synonymous TBL1XR1 mutation alters Wnt signaling activity.Dysregulated nitric oxide signaling as a candidate mechanism of fragile X syndrome and other neuropsychiatric disorders.Schizophrenia genetics: emerging themes for a complex disorder.Architects of the genome: CHD dysfunction in cancer, developmental disorders and neurological syndromesThe discovery of integrated gene networks for autism and related disorders.Psychopathology and cognitive performance in individuals with membrane-associated guanylate kinase mutations: a functional network phenotyping study.A review of study designs and statistical methods for genomic epidemiology studies using next generation sequencing.The contribution of protein intrinsic disorder to understand the role of genetic variants uncovered by autism spectrum disorders exome studies.Genetic Evaluation of Schizophrenia Using the Illumina HumanExome ChipPTP1B inhibition suggests a therapeutic strategy for Rett syndromeSimilarities and Differences in Decision-Making Impairments between Autism Spectrum Disorder and Schizophrenia.CRISPR/Cas9-mediated heterozygous knockout of the autism gene CHD8 and characterization of its transcriptional networks in neurodevelopment.Whole-Genome Sequencing Suggests Schizophrenia Risk Mechanisms in Humans with 22q11.2 Deletion SyndromeIdentification and functional characterization of rare SHANK2 variants in schizophrenia.POGZ truncating alleles cause syndromic intellectual disability.The intolerance to functional genetic variation of protein domains predicts the localization of pathogenic mutations within genes.A spectral approach integrating functional genomic annotations for coding and noncoding variants.Molecular subtyping and improved treatment of neurodevelopmental disease.De Novo Synonymous Mutations in Regulatory Elements Contribute to the Genetic Etiology of Autism and SchizophreniaGenes with de novo mutations are shared by four neuropsychiatric disorders discovered from NPdenovo databaseIncreased abundance of translation machinery in stem cell-derived neural progenitor cells from four schizophrenia patients.
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P2860
De novo mutations in schizophrenia implicate chromatin remodeling and support a genetic overlap with autism and intellectual disability
description
2014 nî lūn-bûn
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2014 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2014 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2014年の論文
@ja
2014年論文
@yue
2014年論文
@zh-hant
2014年論文
@zh-hk
2014年論文
@zh-mo
2014年論文
@zh-tw
2014年论文
@wuu
name
De novo mutations in schizophr ...... sm and intellectual disability
@ast
De novo mutations in schizophr ...... sm and intellectual disability
@en
type
label
De novo mutations in schizophr ...... sm and intellectual disability
@ast
De novo mutations in schizophr ...... sm and intellectual disability
@en
prefLabel
De novo mutations in schizophr ...... sm and intellectual disability
@ast
De novo mutations in schizophr ...... sm and intellectual disability
@en
P2093
P2860
P50
P921
P356
P1433
P1476
De novo mutations in schizophr ...... sm and intellectual disability
@en
P2093
E Antoniou
E Kelleher
S E McCarthy
P2860
P2888
P304
P356
10.1038/MP.2014.29
P407
P50
P577
2014-04-29T00:00:00Z