Aspartic acid at position 57 of the HLA-DQ beta chain protects against type I diabetes: a family study - Test2 - elhamkhani - TriplyDB

Aspartic acid at position 57 of the HLA-DQ beta chain protects against type I diabetes: a family study

Aspartic acid at position 57 of the HLA-DQ beta chain protects against type I diabetes: a family study

http://www.wikidata.org/entity/Q33663073

about

The A3 allele of the HLA-DQA1 locus is associated with susceptibility to type 1 diabetes in Japanese Allelic variants of the human putative peptide transporter involved in antigen processing A specific HLA-DP beta allele is associated with pauciarticular juvenile rheumatoid arthritis but not adult rheumatoid arthritis Immunogenetics of type 1 diabetes mellitus Familial predisposition of type 1 diabetes mellitus in Japan, a country with low incidence. Japan Diabetes Society Data Committee for Childhood Diabetes.HLA-DRB1*15:01-DQA1*01:02-DQB1*06:02 Haplotype Protects Autoantibody-Positive Relatives From Type 1 Diabetes Throughout the Stages of Disease Progression Autoreactivity of T cells from nonobese diabetic mice: an I-Ag7-dependent reaction.Natural peptides selected by diabetogenic DQ8 and murine I-A(g7) molecules show common sequence specificity.Cellular immune mechanisms in chronic autoimmune thrombocytopenic purpura (ATP).HLA-DR antigens and HLA-DQ beta chain polymorphism in susceptibility to rheumatoid arthritis Masked and overt autoantibodies specific to the DPD epitope of 65-kDa glutamate decarboxylase (GAD65-DPD) are associated with preserved β-cell functional reserve in ketosis-prone diabetes.Autoimmune responses in T1DM: quantitative methods to understand onset, progression, and prevention of disease Worldwide differences in the incidence of type I diabetes are associated with amino acid variation at position 57 of the HLA-DQ beta chain Possible deletion of a developmentally regulated heavy-chain variable region gene in autoimmune diseases.Allele-specific enzymatic amplification of beta-globin genomic DNA for diagnosis of sickle cell anemia Milk and diabetes.Screen and clean: a tool for identifying interactions in genome-wide association studies Shared molecular amino acid signature in the HLA-DR peptide binding pocket predisposes to both autoimmune diabetes and thyroiditis.Genetic susceptibility to autoimmune thyroid disease: past, present, and future Major histocompatibility complex class III genes and susceptibility to immunoglobulin A deficiency and common variable immunodeficiency.Newborn HLA-DR,DQ genotype screening: age- and ethnicity-specific type 1 diabetes risk estimates.Thymus-specific deletion of insulin induces autoimmune diabetes.Differences in self-peptide binding between T1D-related susceptible and protective DR4 subtypes.Perspective on antigen processing and presentation.Specificity of peptide selection by antigen-presenting cells homozygous or heterozygous for expression of class II MHC molecules: The lack of competition Cell-surface MHC density profiling reveals instability of autoimmunity-associated HLA.The contribution of immune regulatory and thyroid specific genes to the etiology of Graves' and Hashimoto's diseases.Age-dependent HLA genetic heterogeneity of type 1 insulin-dependent diabetes mellitus.Priming and effector dependence on insulin B:9-23 peptide in NOD islet autoimmunity.RFLP analysis of HLA-DR beta and -DQ beta genes in the Korean patients with insulin-dependent diabetes mellitus Prediction and prevention of type 1 diabetes: update on success of prediction and struggles at prevention Molecular analysis of HLA-DQB1 alleles in childhood common acute lymphoblastic leukaemia.Modeling dynamic changes in type 1 diabetes progression: quantifying beta-cell variation after the appearance of islet-specific autoimmune responses.Polymorphic DQ alpha and DQ beta interactions dictate HLA class II determinants of allo-recognition.Analysis of the role of variation of major histocompatibility complex class II expression on nonobese diabetic (NOD) peripheral T cell response The etiology of autoimmune thyroid disease: a story of genes and environment Genetic determinants of type 1 diabetes across populations.Mutagenesis and expression of putative class II susceptibility genes: a "reverse immunogenetics" approach to analysis of HLA and disease.Genetic and epigenetic mechanisms in thyroid autoimmunity.On the use of general control samples for genome-wide association studies: genetic matching highlights causal variants.

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P2860

Aspartic acid at position 57 of the HLA-DQ beta chain protects against type I diabetes: a family study

http://www.wikidata.org/entity/Q33663073

description

1988 nî lūn-bûn

@nan

1988 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած

@hyw

1988 թվականի նոյեմբերին հրատարակված գիտական հոդված

@hy

1988年の論文

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1988年論文

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1988年論文

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1988年論文

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1988年論文

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1988年論文

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1988年论文

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name

Aspartic acid at position 57 o ...... ype I diabetes: a family study

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Aspartic acid at position 57 o ...... ype I diabetes: a family study

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Aspartic acid at position 57 o ...... ype I diabetes: a family study

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Aspartic acid at position 57 o ...... ype I diabetes: a family study

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Aspartic acid at position 57 o ...... ype I diabetes: a family study

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Proceedings of the National Academy of Sciences of the United States of America

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Aspartic acid at position 57 o ...... ype I diabetes: a family study

@en

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H O McDevitt

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J A Todd

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J S Dorman

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M Trucco

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P A Morel

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P2860

Primer-directed enzymatic amplification of DNA with a thermostable DNA polymerase

Type I diabetes mellitus. A chronic autoimmune disease.

HLA DR antigens and susceptibility to insulin-dependent diabetes mellitus.

Genetics of Type I diabetes mellitus: a single, recessive predisposition gene mapping between HLA-B and GLO. With an appendix on the estimation of selection bias.

Molecular diversity of HLA-DR4 haplotypes

Six HLA-D region alpha-chain genes on human chromosome 6: polymorphisms and associations of DC alpha-related sequences with DR types

The role of viruses in the pathogenesis of pancreatic disease and diabetes mellitus.

High-affinity fluorescent peptide binding to I-Ad in lipid membranes.

Use of pooled DNA samples to detect linkage disequilibrium of polymorphic restriction fragments and human disease: studies of the HLA class II loci.

Identification of a polymorphic variant associated with HLA-DQw3 and characterized by specific restriction sites within the DQ beta-chain gene.

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8111-8115

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scholarly article

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10.1073/PNAS.85.21.8111

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21

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85

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1988-11-01T00:00:00Z

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19969010

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3186714

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P921

type-1 diabetes

P932

282365

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