Replication of an association of variation in the FOXO3A gene with human longevity using both case-control and longitudinal data.
about
We are ageingFinding Ponce de Leon's Pill: Challenges in Screening for Anti-Aging MoleculesLong live FOXO: unraveling the role of FOXO proteins in aging and longevityThe search for longevity and healthy aging genes: insights from epidemiological studies and samples of long-lived individualsThe Role of the Transcription Factor Foxo3 in Hearing Maintenance: Informed Speculation on a New Player in the CochleaIntegration of β-catenin, sirtuin, and FOXO signaling protects from mutant huntingtin toxicityFoxO6 regulates memory consolidation and synaptic functionSevere hearing loss and outer hair cell death in homozygous Foxo3 knockout mice after moderate noise exposure.Human longevity and variation in GH/IGF-1/insulin signaling, DNA damage signaling and repair and pro/antioxidant pathway genes: cross sectional and longitudinal studiesSpermidine coupled with exercise rescues skeletal muscle atrophy from D-gal-induced aging rats through enhanced autophagy and reduced apoptosis via AMPK-FOXO3a signal pathway.Transcriptional regulation of Caenorhabditis elegans FOXO/DAF-16 modulates lifespan.Association between FOXO3A gene polymorphisms and human longevity: a meta-analysis.Adjustment for smoking does not alter the FOXO3A association with longevity.Contribution of genetic polymorphisms on functional status at very old age: a gene-based analysis of 38 genes (311 SNPs) in the oxidative stress pathway.Human longevity and variation in DNA damage response and repair: study of the contribution of sub-processes using competitive gene-set analysis.Gene set analysis of GWAS data for human longevity highlights the relevance of the insulin/IGF-1 signaling and telomere maintenance pathways.Birth cohort differences in the prevalence of longevity-associated variants in APOE and FOXO3A in Danish long-lived individuals.Genetic variants in PVRL2-TOMM40-APOE region are associated with human longevity in a Han Chinese population.GWAS of longevity in CHARGE consortium confirms APOE and FOXO3 candidacy.Resveratrol prevents oxidative stress-induced senescence and proliferative dysfunction by activating the AMPK-FOXO3 cascade in cultured primary human keratinocytes.Longevity effect of IGF-1R(+/-) mutation depends on genetic background-specific receptor activation.Association study of FOXO3A SNPs and aging phenotypes in Danish oldest-old individuals.Specific suppression of insulin sensitivity in growth hormone receptor gene-disrupted (GHR-KO) mice attenuates phenotypic features of slow agingNew genes that extend Caenorhabditis elegans' lifespan in response to reproductive signals.DAF-16 target identification in C. elegans: past, present and future.Genome-wide association study identifies a single major locus contributing to survival into old age; the APOE locus revisited.Macrophage migration inhibitory factor confers resistance to senescence through CD74-dependent AMPK-FOXO3a signaling in mesenchymal stem cells.Using C. elegans for aging research.Healthy aging - insights from DrosophilaDiverse roles of growth hormone and insulin-like growth factor-1 in mammalian aging: progress and controversies.Epidemiological, genetic and epigenetic aspects of the research on healthy ageing and longevity.Human longevity and common variations in the LMNA gene: a meta-analysisCandidate gene resequencing to identify rare, pedigree-specific variants influencing healthy aging phenotypes in the long life family study.Age-specific variation in immune response in Drosophila melanogaster has a genetic basis.Genetic Association Analysis of Common Variants in FOXO3 Related to Longevity in a Chinese Population.Nutraceutical interventions for promoting healthy aging in invertebrate modelsLongevity GWAS Using the Drosophila Genetic Reference Panel.The transcriptional landscape of age in human peripheral blood.The epidemiology of longevity and exceptional survivalFOXO1 inhibits osteosarcoma oncogenesis via Wnt/β-catenin pathway suppression.
P2860
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P2860
Replication of an association of variation in the FOXO3A gene with human longevity using both case-control and longitudinal data.
description
2010 nî lūn-bûn
@nan
2010 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Replication of an association ...... control and longitudinal data.
@ast
Replication of an association ...... control and longitudinal data.
@en
type
label
Replication of an association ...... control and longitudinal data.
@ast
Replication of an association ...... control and longitudinal data.
@en
prefLabel
Replication of an association ...... control and longitudinal data.
@ast
Replication of an association ...... control and longitudinal data.
@en
P2093
P2860
P50
P1433
P1476
Replication of an association ...... control and longitudinal data.
@en
P2093
Lene Christiansen
Matt McGue
Tinna Stevnsner
Vilhelm A Bohr
P2860
P304
P356
10.1111/J.1474-9726.2010.00627.X
P577
2010-10-21T00:00:00Z