Systematic mapping of functional enhancer-promoter connections with CRISPR interference.
about
CRISPRi-based genome-scale identification of functional long noncoding RNA loci in human cells.Genome-scale CRISPR-Cas9 knockout and transcriptional activation screeningFunctional interrogation of non-coding DNA through CRISPR genome editing.CRISPR-Cas9 epigenome editing enables high-throughput screening for functional regulatory elements in the human genome.Chromatin-enriched lncRNAs can act as cell-type specific activators of proximal gene transcription.Capturing genomic relationships that matterApplication of CRISPR/Cas9 to the study of brain development and neuropsychiatric disease.Recent advances in high-throughput approaches to dissect enhancer functionCRISPR-FOCUS: A web server for designing focused CRISPR screening experiments.Identification of an Enhancer Critical for the ephirn-A5 Gene Expression in the Posterior Region of the Mesencephalon.A tiling-deletion-based genetic screen for cis-regulatory element identification in mammalian cells.Three-dimensional genome architecture and emerging technologies: looping in disease.Enhancer connectome in primary human cells identifies target genes of disease-associated DNA elements.pgRNAFinder: a web-based tool to design distance independent paired-gRNA.Global Inhibition with Specific Activation: How p53 and MYC Redistribute the Transcriptome in the DNA Double-Strand Break Response.Human gene essentiality.CRISPR-Cas9-mediated functional dissection of 3'-UTRs.Making the cut in the dark genome.CRISPRi and CRISPRa Screens in Mammalian Cells for Precision Biology and Medicine.CRISPR Genome Engineering for Human Pluripotent Stem Cell Research.Forging our understanding of lncRNAs in the brain.ENCoRE: an efficient software for CRISPR screens identifies new players in extrinsic apoptosis.Functional assessment of human enhancer activities using whole-genome STARR-sequencing.Promoter-enhancer interactions identified from Hi-C data using probabilistic models and hierarchical topological domains.Am I ready for CRISPR? A user's guide to genetic screens.CRISPR-based strategies for studying regulatory elements and chromatin structure in mammalian gene control.Beyond editing to writing large genomes.Target Discovery for Precision Medicine Using High-Throughput Genome Engineering.From Reductionism to Holism: Toward a More Complete View of Development Through Genome Engineering.High-Throughput Approaches to Pinpoint Function within the Noncoding Genome.Methods and Applications of CRISPR-Mediated Base Editing in Eukaryotic Genomes.A CRISPR reimagining: New twists and turns of CRISPR beyond the genome-engineering revolution.Multiplex Enhancer Interference Reveals Collaborative Control of Gene Regulation by Estrogen Receptor α-Bound Enhancers.Genome Engineering for Personalized Arthritis Therapeutics.Genome-scale activation screen identifies a lncRNA locus regulating a gene neighbourhood.Dissection and function of autoimmunity-associated TNFAIP3 (A20) gene enhancers in humanized mouse models.The Impact of CRISPR/Cas9 Technology on Cardiac Research: From Disease Modelling to Therapeutic Approaches.Chromatin dependencies in cancer and inflammation.Functional Classification and Experimental Dissection of Long Noncoding RNAs.A Myc enhancer cluster regulates normal and leukaemic haematopoietic stem cell hierarchies.
P2860
Q33573686-E03921A2-E00F-4DB8-9B2D-121AD3DF1924Q34553929-3B2A637B-65E0-4F67-BF1D-E0C608DFA4D4Q36306820-CF577040-0955-4EBF-88E5-EFE2A114EE02Q36331722-25CD5747-72F4-4844-B07B-2063FFEB310CQ38699849-E6295FFC-6EEA-4436-A49B-2DD2228C7956Q39025708-533191D1-7762-4683-99BF-D8529EB9E5B5Q39333331-82BB5E31-770F-434C-906A-229CF2B2FB1AQ39424726-81BF1F48-B5E5-4734-867A-A0D57ACD1366Q40066344-05595EDF-8004-49A3-AEB9-FE0E61556208Q41098185-348A59EA-8063-4777-B59C-959F54FF8F9BQ42333586-8CCA4A76-9DE0-4E81-B65E-30F669B2F891Q42368505-A5A1D20A-2CC7-4559-97FA-31F73FAF73B1Q42692866-DEAE1820-EA92-4AAB-BDC1-C284CDE3F33BQ42694047-504A4096-AA7F-438E-BC60-9AE370B6EA05Q42777559-D149E721-7344-41CA-AD2E-278EB347741CQ46065137-A2164485-553E-4A49-AD4C-0DD54426DECEQ46067907-EBC5ECA8-202C-4527-9C0B-479307E61D75Q46103297-03D06F9E-62B1-4AC0-B45C-D3E4D5234565Q46190066-7A8C4158-356F-4EEA-9A89-8C6AE589C535Q46522290-FE3A443C-FE12-43B0-98FE-86852563BC6CQ46569544-3C1F57EF-C7B3-4E15-8A2C-6EDFDEA6FE10Q47096845-DCB6FC2C-760E-4AA0-87AC-D59B72102D88Q47105936-624D8FAD-8198-4398-AC88-A23E46D6627AQ47158127-FA616D62-5907-47AA-9AA7-C92188072CD7Q47281660-E3FAC86A-2A72-4DFB-8602-EDA5D1B9E590Q47291540-202B8FEE-D54A-4574-BA2E-AFC837CCD9EDQ47324234-3864BB2A-0A47-4AD9-B6C3-BE1323D684E4Q47356354-648DD792-3092-4FB8-825F-DB7DB1F446FAQ47356373-71915D69-2957-4777-8668-81ED7C340C27Q47594697-8CAFDF3B-5E33-4A7C-BB7A-368EA028A9C9Q47594709-54678AF0-D994-4A63-8505-D03259BCA528Q47659785-37AE446D-5362-4164-A555-C9BA74086DD4Q47665602-1505F1DD-465D-4FB9-B18E-29F2D3284777Q47697061-E1372EB6-87DE-4020-8526-538FA554FD01Q47813986-A740B93A-483D-4DB0-BB5C-59FBFEC99FFCQ49216526-5D1FB618-FB82-48DF-9BDE-217C0EF20A84Q49432567-04945B58-7C9F-4A32-82EE-1154777A7AA0Q49565575-A9622E61-E0DA-4061-A2EF-542CD6BFBAFCQ49649796-DF65D6D2-7978-4AB5-8694-7483FE6D41F6Q50001782-A53C3137-7E58-4091-A1B6-25CCF59A3BF2
P2860
Systematic mapping of functional enhancer-promoter connections with CRISPR interference.
description
2016 nî lūn-bûn
@nan
2016 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2016 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2016年の論文
@ja
2016年論文
@yue
2016年論文
@zh-hant
2016年論文
@zh-hk
2016年論文
@zh-mo
2016年論文
@zh-tw
2016年论文
@wuu
name
Systematic mapping of functional enhancer-promoter connections with CRISPR interference.
@ast
Systematic mapping of functional enhancer-promoter connections with CRISPR interference.
@en
type
label
Systematic mapping of functional enhancer-promoter connections with CRISPR interference.
@ast
Systematic mapping of functional enhancer-promoter connections with CRISPR interference.
@en
prefLabel
Systematic mapping of functional enhancer-promoter connections with CRISPR interference.
@ast
Systematic mapping of functional enhancer-promoter connections with CRISPR interference.
@en
P2093
P2860
P50
P356
P1433
P1476
Systematic mapping of functional enhancer-promoter connections with CRISPR interference.
@en
P2093
Brian Cleary
Charles P Fulco
Elizabeth M Perez
Glen Munson
Jesse M Engreitz
Michael Kane
Rockwell Anyoha
P2860
P304
P356
10.1126/SCIENCE.AAG2445
P407
P577
2016-09-29T00:00:00Z