Partial D-amino acid substitution: Improved enzymatic stability and preserved Ab recognition of a MUC2 epitope peptide
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Inhibiting α-synuclein oligomerization by stable cell-penetrating β-synuclein fragments recovers phenotype of Parkinson's disease model fliesCompetitive Mirror Image Phage Display Derived Peptide Modulates Amyloid Beta Aggregation and ToxicitySquaric acid mediated chemoselective PEGylation of proteins: reactivity of single-step-activated α-amino poly(ethylene glycol)s.Bacillus anthracis peptidoglycan stimulates an inflammatory response in monocytes through the p38 mitogen-activated protein kinase pathway.Design of proteolytically stable RI-anchoring disruptor peptidomimetics for in vivo studies of anchored type I protein kinase A-mediated signalling.Revised Backbone-Virtual-Bond-Angle Potentials to Treat the l- and d-Amino Acid Residues in the Coarse-Grained United Residue (UNRES) Force FieldL-Tyrosine Confers Residualizing Properties to a d-Amino Acid-Rich Residualizing Peptide for Radioiodination of Internalizing Antibodies.Improved tumor targeting of anti-HER2 nanobody through N-succinimidyl 4-guanidinomethyl-3-iodobenzoate radiolabelingDe-novo design of antimicrobial peptides for plant protection.Novel Peptidomimetics for Inhibition of HER2:HER3 Heterodimerization in HER2-Positive Breast CancerNox Inhibitors & Therapies: Rational Design of Peptidic and Small Molecule InhibitorsD-Amino Acid Substitution of Peptide-Mediated NF-κB Suppression in mdx Mice Preserves Therapeutic Benefit in Skeletal Muscle, but Causes Kidney Toxicity.Cyclisation increases the stability of the sea anemone peptide APETx2 but decreases its activity at acid-sensing ion channel 3Post-translational Introduction of D-Alanine into Ribosomally Synthesized Peptides by the Dehydroalanine Reductase NpnJInhibition of cell adhesion and immune responses in the mouse model of collagen-induced arthritis with a peptidomimetic that blocks CD2-CD58 interface interactions.New analogs of the clinical complement inhibitor compstatin with subnanomolar affinity and enhanced pharmacokinetic propertiesPeptide Backbone Composition and Protease Susceptibility: Impact of Modification Type, Position, and Tandem Substitution.Metabolism of peptide reporters in cell lysates and single cellsEngineering the meso-diaminopimelate dehydrogenase from Symbiobacterium thermophilum by site saturation mutagenesis for D-phenylalanine synthesisRationally designed peptide regulators of protein kinase C.Selective recapitulation of conserved and nonconserved regions of putative NOXA1 protein activation domain confers isoform-specific inhibition of Nox1 oxidase and attenuation of endothelial cell migration.Inspiration from the mirror: D-amino acid containing peptides in biomedical approaches.Structure-activity relationships of peptidomimetics that inhibit PPI of HER2-HER3.Molecular-targeted approaches to reduce renal accumulation of nephrotoxic drugs.Peptides and peptide conjugates: therapeutics on the upward path.Basics and recent advances in peptide and protein drug delivery.Strategic approaches to optimizing peptide ADME propertiesD-amino acid based protein arginine deiminase inhibitors: Synthesis, pharmacokinetics, and in cellulo efficacy.The Unexpected Advantages of Using D-Amino Acids for Peptide Self- Assembly into Nanostructured Hydrogels for Medicine.Constrained Cyclic Peptides as Immunomodulatory Inhibitors of the CD2:CD58 Protein-Protein Interaction.Improvement of in vivo antimicrobial activity of HBcARD peptides by D-arginine replacement.Redesigning the stereospecificity of tyrosyl-tRNA synthetase.The immunogenicity of a novel cytotoxic T lymphocyte epitope from tumor antigen PL2L60 could be enhanced by 4-chlorophenylalanine substitution at position 1.Mechanistic Understanding of Lanthipeptide Biosynthetic Enzymes.Microvascular NADPH oxidase in health and disease.Initiating translation with D-amino acids.Structure-function relationships of protein-lipopeptide complexes and influence on immunogenicity.Designer D-form self-assembling peptide scaffolds promote the proliferation and migration of rat bone marrow-derived mesenchymal stem cells.Effects of cyclic lipodepsipeptide structural modulation on stability, antibacterial activity, and human cell toxicity.Multilayered Nanoparticles for Gene Delivery Used to Reprogram Human Foreskin Fibroblasts to Neurospheres.
P2860
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P2860
Partial D-amino acid substitution: Improved enzymatic stability and preserved Ab recognition of a MUC2 epitope peptide
description
2005 nî lūn-bûn
@nan
2005 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2005 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
name
Partial D-amino acid substitut ...... tion of a MUC2 epitope peptide
@ast
Partial D-amino acid substitut ...... tion of a MUC2 epitope peptide
@en
type
label
Partial D-amino acid substitut ...... tion of a MUC2 epitope peptide
@ast
Partial D-amino acid substitut ...... tion of a MUC2 epitope peptide
@en
prefLabel
Partial D-amino acid substitut ...... tion of a MUC2 epitope peptide
@ast
Partial D-amino acid substitut ...... tion of a MUC2 epitope peptide
@en
P2093
P2860
P356
P1476
Partial D-amino acid substitut ...... tion of a MUC2 epitope peptide
@en
P2093
Erzsébet Fellinger
Ferenc Hudecz
Regina Tugyi
P2860
P304
P356
10.1073/PNAS.0407677102
P407
P577
2005-01-03T00:00:00Z