Antineoplastic effects of an Aurora B kinase inhibitor in breast cancer. - Test2 - elhamkhani - TriplyDB

Antineoplastic effects of an Aurora B kinase inhibitor in breast cancer.

Antineoplastic effects of an Aurora B kinase inhibitor in breast cancer.

http://www.wikidata.org/entity/Q33732173

about

BPR1K653, a novel Aurora kinase inhibitor, exhibits potent anti-proliferative activity in MDR1 (P-gp170)-mediated multidrug-resistant cancer cells GSAASeqSP: a toolset for gene set association analysis of RNA-Seq data The Discovery of Novel Biomarkers Improves Breast Cancer Intrinsic Subtype Prediction and Reconciles the Labels in the METABRIC Data Set.Expression of aurora kinase A is associated with metastasis-free survival in node-negative breast cancer patients.The transcription factor YY1 is a novel substrate for Aurora B kinase at G2/M transition of the cell cycle Update on aurora kinase inhibitors in gynecologic malignancies.Update on Aurora Kinase Targeted Therapeutics in Oncology.Differentially expressed transcripts and dysregulated signaling pathways and networks in African American breast cancer.Aurora kinase B is important for antiestrogen resistant cell growth and a potential biomarker for tamoxifen resistant breast cancer Construction and characterization of novel, completely human serine protease therapeutics targeting Her2/neu Aurora kinase A and B as new treatment targets in aromatase inhibitor-resistant breast cancer cells.HSET overexpression fuels tumor progression via centrosome clustering-independent mechanisms in breast cancer patients Aurora B kinase is a potent and selective target in MYCN-driven neuroblastoma Aurora kinase inhibitors as anticancer molecules.QuIN: A Web Server for Querying and Visualizing Chromatin Interaction Networks Aurora B kinase phosphorylates and instigates degradation of p53 Regulating the stability and localization of CDK inhibitor p27(Kip1) via CSN6-COP1 axis.Aurora B is regulated by the mitogen-activated protein kinase/extracellular signal-regulated kinase (MAPK/ERK) signaling pathway and is a valuable potential target in melanoma cells.COP1 enhances ubiquitin-mediated degradation of p27Kip1 to promote cancer cell growth.Effects of Activating Mutations on EGFR Cellular Protein Turnover and Amino Acid Recycling Determined Using SILAC Mass Spectrometry FBXW7 is involved in Aurora B degradation.Predictive biomarkers of sensitivity to the aurora and angiogenic kinase inhibitor ENMD-2076 in preclinical breast cancer models.Aurora kinase targeting in lung cancer reduces KRAS-induced transformation.Compartment model predicts VEGF secretion and investigates the effects of VEGF trap in tumor-bearing mice.SU6668 suppresses proliferation of triple negative breast cancer cells through down-regulating MTDH expression.Inhibition of Aurora-B suppresses osteosarcoma cell migration and invasion.Aurora kinase inhibitor patents and agents in clinical testing: an update (2009-10).Barasertib (AZD1152), a Small Molecule Aurora B Inhibitor, Inhibits the Growth of SCLC Cell Lines In Vitro and In Vivo.Microarray analysis revealed different gene expression patterns in HepG2 cells treated with low and high concentrations of the extracts of Anacardium occidentale shoots.Antitumour activity of AMG 900 alone or in combination with histone deacetylase inhibitor SaHa on medulloblastoma cell lines.Sequential treatment with aurora B inhibitors enhances cisplatin-mediated apoptosis via c-Myc.AZD1152-HQPA induces growth arrest and apoptosis in androgen-dependent prostate cancer cell line (LNCaP) via producing aneugenic micronuclei and polyploidy.A Vector-Based Short Hairpin RNA Targeting Aurora B Suppresses Human Prostatic Carcinoma Growth.Preclinical studies with JAA-F11 anti-Thomsen-Friedenreich monoclonal antibody for human breast cancer.Aurora B inhibitor barasertib and cytarabine exert a greater-than-additive cytotoxicity in acute myeloid leukemia cells.Canine osteosarcoma cells exhibit resistance to aurora kinase inhibitors.Aurora kinase inhibitor AZD1152 has an additional effect of platinum on a sequential application at the human ovarian cancer cell line SKOV3.Inhibition of Aurora kinases enhances chemosensitivity to temozolomide and causes radiosensitization in glioblastoma cells.APIO-EE-9 is a novel Aurora A and B antagonist that suppresses esophageal cancer growth in a PDX mouse model.Protein Kinase Targets in Breast Cancer.

P2860

Q28476664-AFB6ADAA-1554-40A6-97E3-2D7CC11B395B Q30850769-5A298F88-A588-4EB6-9F77-3F8557C824B8 Q30978083-1453B2F5-BDAF-4DC7-A669-A3EE822B76C3 Q34491749-6E42E510-7091-4BED-A8BF-2E92E1432CAD Q34505702-F95F1091-F1C0-43DC-9DB3-92E6C9FFE12C Q34576017-33888FE1-3CED-48D5-AB4C-2339B180A8A5 Q34941504-7AAD1F20-CA83-406B-A56E-98D84CC873F7 Q35064200-F64D59A0-9D7A-422D-AEF4-AE8201AC4E53 Q35356178-A8E49616-32DE-479E-8C55-90D67000DA01 Q35541200-B1321B9C-7318-4521-97FB-CADCE6BB9C37 Q35558610-73E378B1-776C-48BF-A5DD-EF659E3E8BEA Q35742468-C8A947CD-0C05-46BA-B441-A1BD2D4BAAF0 Q35819646-261EEB9F-2F55-4891-A470-1246AE27FCA1 Q35850203-03DB7A9A-0F4B-4358-82AC-342FD627D12C Q36059754-79E8206B-1D48-4008-AE98-AEBD44448A97 Q36066322-BD5AC6AE-0031-490B-A4B1-8B890CAE025A Q36183877-FCDBCE9A-0420-4115-88C2-3BB014114590 Q36215925-7B176A42-E44C-4EA4-BF17-E7B4DE5947A8 Q36260630-AC35E230-525B-481E-8D5C-E2C1E8C73F52 Q36353093-C70C3104-62F3-4C8C-AC19-730F3523807A Q36426514-28525F98-E1E1-4E11-AF02-BABEF3E501B7 Q36511204-7CAC7F7F-F2D4-4912-8CA9-5368A377E089 Q36538710-8C420983-E405-4C42-BA87-773982B2D4EE Q37054876-90E23FDB-636E-4315-AFAD-887A3A9DCD69 Q37351958-36CF624C-2A35-4863-856E-8EB3CEC7962C Q37575064-E26F8A7F-7C4F-4D3E-A04F-03DD01CFC664 Q37876882-420E4D1A-AEFE-4CEC-A590-F5334F3C3C6D Q38753586-FAEBD9CA-C196-4D11-88DC-140B58A28611 Q38770592-3F26BC1E-AFCF-4D33-B46A-86DAD9E91B06 Q38872009-052D924A-69FE-4B5B-9E91-ED2AEE36232D Q38939084-0774467B-A7C2-4C4B-A842-C58CFADAEBB5 Q38951017-B461D451-E9E9-44CD-B2D0-4A4A6C7F5252 Q39014121-E61C73F9-EC45-4E70-869A-B175A36E7242 Q39021852-DD0FE608-2D1E-4F1B-93C1-F4016AD7C97E Q39171321-6A8BA61E-C0B5-45C8-9D66-B5C6BE0F4A90 Q39194457-CF8C8E33-F4EE-4F27-BF82-8271DAB90B23 Q39198408-824AFCDE-4AD6-4308-9C4A-141076ED2B61 Q39429784-88C9D76E-04B5-4EC7-8E37-79431B14F96E Q41593187-7808CF76-8C37-47CE-AEC4-B9910A659217 Q47351355-008D339C-878C-49AE-BBF7-5DB47B3E2CEF

P2860

Antineoplastic effects of an Aurora B kinase inhibitor in breast cancer.

http://www.wikidata.org/entity/Q33732173

description

2010 nî lūn-bûn

@nan

2010 թուականի Փետրուարին հրատարակուած գիտական յօդուած

@hyw

2010 թվականի փետրվարին հրատարակված գիտական հոդված

@hy

2010年の論文

@ja

2010年論文

@yue

2010年論文

@zh-hant

2010年論文

@zh-hk

2010年論文

@zh-mo

2010年論文

@zh-tw

2010年论文

@wuu

name

Antineoplastic effects of an Aurora B kinase inhibitor in breast cancer.

@ast

Antineoplastic effects of an Aurora B kinase inhibitor in breast cancer.

@en

type

label

Antineoplastic effects of an Aurora B kinase inhibitor in breast cancer.

@ast

Antineoplastic effects of an Aurora B kinase inhibitor in breast cancer.

@en

prefLabel

Antineoplastic effects of an Aurora B kinase inhibitor in breast cancer.

@ast

Antineoplastic effects of an Aurora B kinase inhibitor in breast cancer.

@en

P1433

Q33732173-6B289C67-2A79-4E9C-9855-6928DC58B1F6

P1476

Q33732173-6CC901C1-79FA-4558-AEEF-49083CF9BDC8

P2093

Q33732173-1A9BC622-476A-48E7-91F7-6FA561C66C90

Q33732173-202B8998-892C-41B0-A484-A17F96121E7B

Q33732173-2883A771-67B2-4E2A-B91F-45472DAF3461

Q33732173-402EC798-A44C-4BB7-B583-EE287C26EC4D

Q33732173-625870C3-AE33-48F4-9EF3-1A9DE6E943CB

Q33732173-83FA6F96-60CE-4460-A270-91F7D480F022

Q33732173-DDC10103-DCC9-4125-B689-3A04952920AC

Q33732173-F7AC82A7-BE15-4EAC-AAEB-48A44565099C

P2860

Q33732173-0C82F2BF-6962-41DB-B3B7-77D6F3C2E13F

Q33732173-1E8556F7-167D-4ED0-98DE-84EA3C323525

Q33732173-25490F0A-C00C-4518-8C9C-1B50C161AD60

Q33732173-25F71A8D-6F3B-44F9-85DF-04C69A702F38

Q33732173-27E9D7DC-8DEF-408D-88D1-2557A5C7A175

Q33732173-41A269DE-F935-41C7-AF71-6A3EB9A1F9A0

Q33732173-42AD82F0-5E0C-4340-A1F9-FB124ED51F06

Q33732173-4A9988B2-81D1-47AF-943A-0B4BEFBA7F33

Q33732173-4A9D02D9-0672-498B-A0E5-38C1D2F8AF78

Q33732173-4B0B5F75-A654-4E1F-9872-0657BE0BA4C0

P2888

Q33732173-AAAD4F3F-B0E7-4CE5-A71D-F66189CCC247

P304

Q33732173-63079D29-2248-43C8-8183-67C2EFA30B36

P31

Q33732173-846B3753-E3FC-495B-91A7-5AA753DEFFCF

P356

Q33732173-C0DE1E4A-A095-44FE-9899-6FEDD61D8C7C

P478

Q33732173-44C68170-FF3F-4D1C-950F-2FC61B0B2381

P577

Q33732173-7AD922EA-9BCB-4520-8D5B-7244D8B37588

P5875

Q33732173-7B6A5ADA-9898-4B9C-8306-711E96B89710

P6179

Q33732173-E7772363-7DCC-41A8-BCC4-656BC12048F1

P698

Q33732173-2A38542C-7835-4467-8FD2-6DBAD16258C6

P932

Q33732173-9F65C8DA-0CC6-4BAF-81E4-8DBBE118AEC8

P356

P1433

Molecular Cancer

P1476

Antineoplastic effects of an Aurora B kinase inhibitor in breast cancer.

@en

P2093

Christopher P Gully

http://www.w3.org/2001/XMLSchema#string

Edward Wang

http://www.w3.org/2001/XMLSchema#string

Fanmao Zhang

http://www.w3.org/2001/XMLSchema#string

Guermarie Velazquez-Torres

http://www.w3.org/2001/XMLSchema#string

James A Yeung

http://www.w3.org/2001/XMLSchema#string

Jian Chen

http://www.w3.org/2001/XMLSchema#string

Mong-Hong Lee

http://www.w3.org/2001/XMLSchema#string

Sai-Ching Jim Yeung

http://www.w3.org/2001/XMLSchema#string

P2860

Association of the cyclin-dependent kinases and 14-3-3 sigma negatively regulates cell cycle progression

Mitotic phosphorylation of histone H3 is governed by Ipl1/aurora kinase and Glc7/PP1 phosphatase in budding yeast and nematodes

Molecular basis of drug resistance in aurora kinases

Aurora B couples chromosome alignment with anaphase by targeting BubR1, Mad2, and Cenp-E to kinetochores

Aurora-B phosphorylates Histone H3 at serine28 with regard to the mitotic chromosome condensation

A homologue of Drosophila aurora kinase is oncogenic and amplified in human colorectal cancers

The Aurora kinases: role in cell transformation and tumorigenesis.

Roles of Aurora kinases in mitosis and tumorigenesis.

The survivin/Aurora B complex: its role in coordinating tension and attachment.

Aurora kinases in spindle assembly and chromosome segregation.

P2888

P304

42

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1186/1476-4598-9-42

http://www.w3.org/2001/XMLSchema#string

P478

9

http://www.w3.org/2001/XMLSchema#string

P577

2010-02-22T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P5875

41531386

http://www.w3.org/2001/XMLSchema#string

P6179

1042878450

http://www.w3.org/2001/XMLSchema#string

P698

20175926

http://www.w3.org/2001/XMLSchema#string

P932

2839967

http://www.w3.org/2001/XMLSchema#string