Identification of (R)-N-((4-Methoxy-6-methyl-2-oxo-1,2-dihydropyridin-3-yl)methyl)-2-methyl-1-(1-(1-(2,2,2-trifluoroethyl)piperidin-4-yl)ethyl)-1H-indole-3-carboxamide (CPI-1205), a Potent and Selective Inhibitor of Histone Methyltransferase EZH2, S

Identification of (R)-N-((4-Methoxy-6-methyl-2-oxo-1,2-dihydropyridin-3-yl)methyl)-2-methyl-1-(1-(1-(2,2,2-trifluoroethyl)piperidin-4-yl)ethyl)-1H-indole-3-carboxamide (CPI-1205), a Potent and Selective Inhibitor of Histone Methyltransferase EZH2, S

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http://www.wikidata.org/entity/Q33746209
Inhibitors of Protein Methyltransferases and Demethylases.EZH2 inhibitors: a patent review (2014-2016).Follicular lymphoma, a B cell malignancy addicted to epigenetic mutations.EZH2 in Cancer Progression and Potential Application in Cancer Therapy: A Friend or Foe?Recent progress in developing selective inhibitors of protein methyltransferases.Novel orally bioavailable EZH1/2 dual inhibitors with greater antitumor efficacy than an EZH2 selective inhibitor.Structure, mechanism, and regulation of polycomb repressive complex 2.Prognostic implications of polycomb proteins ezh2, suz12, and eed1 and histone modification by H3K27me3 in sarcoma.Discovery of EBI-2511: A Highly Potent and Orally Active EZH2 Inhibitor for the Treatment of Non-Hodgkin's Lymphoma.Distinct Stimulatory Mechanisms Regulate the Catalytic Activity of Polycomb Repressive Complex 2.Epigenetic regulation of cancer progression by EZH2: from biological insights to therapeutic potential.Pyrazole-based inhibitors of enhancer of zeste homologue 2 induce apoptosis and autophagy in cancer cells.Targeting Epigenetic Aberrations in Pancreatic Cancer, a New Path to Improve Patient Outcomes?An Evolutionarily Conserved Structural Platform for PRC2 Inhibition by a Class of Ezh2 Inhibitors.Targeting EZH2 Reprograms Intratumoral Regulatory T Cells to Enhance Cancer Immunity
P2860

Identification of (R)-N-((4-Methoxy-6-methyl-2-oxo-1,2-dihydropyridin-3-yl)methyl)-2-methyl-1-(1-(1-(2,2,2-trifluoroethyl)piperidin-4-yl)ethyl)-1H-indole-3-carboxamide (CPI-1205), a Potent and Selective Inhibitor of Histone Methyltransferase EZH2, S

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http://www.wikidata.org/entity/Q33746209
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2016 nî lūn-bûn
@nan
2016 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2016 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2016年の論文
@ja
2016年論文
@yue
2016年論文
@zh-hant
2016年論文
@zh-hk
2016年論文
@zh-mo
2016年論文
@zh-tw
2016年论文
@wuu
name
Identification of (R)-N-((4-Me ...... tone Methyltransferase EZH2, S
@ast
Identification of (R)-N-((4-Me ...... tone Methyltransferase EZH2, S
@en
type
label
Identification of (R)-N-((4-Me ...... tone Methyltransferase EZH2, S
@ast
Identification of (R)-N-((4-Me ...... tone Methyltransferase EZH2, S
@en
prefLabel
Identification of (R)-N-((4-Me ...... tone Methyltransferase EZH2, S
@ast
Identification of (R)-N-((4-Me ...... tone Methyltransferase EZH2, S
@en
P1433
P1476
P2093
P2860
P304
P31
P356
P407
P433
P478
P50
P577
P698
P932
P356
P1433
P1476
Identification of (R)-N-((4-Me ...... tone Methyltransferase EZH2, S
@en
P2093
P2860
P304
P31
P356
10.1021/ACS.JMEDCHEM.6B01315
P407
P433
P478
P50
P577
P698
P932