The structural complexity of the human BORIS gene in gametogenesis and cancer. - Test2 - elhamkhani - TriplyDB

The structural complexity of the human BORIS gene in gametogenesis and cancer.

The structural complexity of the human BORIS gene in gametogenesis and cancer.

http://www.wikidata.org/entity/Q33747803

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A cell cycle role for the epigenetic factor CTCF-L/BORIS Widespread expression of BORIS/CTCFL in normal and cancer cells Different Effects of BORIS/CTCFL on Stemness Gene Expression, Sphere Formation and Cell Survival in Epithelial Cancer Stem Cells Dose-dependent activation of putative oncogene SBSN by BORIS Hypomethylation of the CTCFL/BORIS promoter and aberrant expression during endometrial cancer progression suggests a role as an Epi-driver gene.High expression of hTERT and stemness genes in BORIS/CTCFL positive cells isolated from embryonic cancer cells.Synergistic effects of combined DNA methyltransferase inhibition and MBD2 depletion on breast cancer cells; MBD2 depletion blocks 5-aza-2'-deoxycytidine-triggered invasiveness Differential regulation of MAGE-A1 promoter activity by BORIS and Sp1, both interacting with the TATA binding protein.Cohesin complexes with a potential to link mammalian meiosis to cancer Coordinated cancer germline antigen promoter and global DNA hypomethylation in ovarian cancer: association with the BORIS/CTCF expression ratio and advanced stage Frequent disruption of chromodomain helicase DNA-binding protein 8 (CHD8) and functionally associated chromatin regulators in prostate cancer Expression of the CTCFL Gene during Mouse Embryogenesis Causes Growth Retardation, Postnatal Lethality, and Dysregulation of the Transforming Growth Factor β Pathway.Expression of the epigenetic factor BORIS (CTCFL) in the human genome Comparative analyses of CTCF and BORIS occupancies uncover two distinct classes of CTCF binding genomic regions.The significance of epigenetic alterations in lung carcinogenesis.BORIS/CTCFL mRNA isoform expression and epigenetic regulation in epithelial ovarian cancer.Genome-Wide Detection of Gene Coexpression Domains Showing Linkage to Regions Enriched with Polymorphic Retrotransposons in Recombinant Inbred Mouse Strains.Brother of the regulator of the imprinted site (BORIS) variant subfamily 6 is involved in cervical cancer stemness and can be a target of immunotherapy.Testis-specific transcriptional regulators selectively occupy BORIS-bound CTCF target regions in mouse male germ cells.Expression analysis of BORIS during pluripotent, differentiated, cancerous, and non-cancerous cell states.Expression of the cancer-testis antigen BORIS correlates with prostate cancer.The cancer-testis antigen BORIS phenocopies the tumor suppressor CTCF in normal and neoplastic cells.The male germ cell gene regulator CTCFL is functionally different from CTCF and binds CTCF-like consensus sites in a nucleosome composition-dependent manner.The downregulation of putative anticancer target BORIS/CTCFL in an addicted myeloid cancer cell line modulates the expression of multiple protein coding and ncRNA genes.Selective inhibition of CTCF binding by iAs directs TET-mediated reprogramming of 5-hydroxymethylation patterns in iAs-transformed cells.Possible prognostic value of BORIS transcript variants ratio in laryngeal squamous cell carcinomas - a pilot study.Increased expression of brother of the regulator of imprinted sites in peripheral blood neutrophils is associated with both benign and malignant breast lesions.BORIS: a key regulator of cancer stemness

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The structural complexity of the human BORIS gene in gametogenesis and cancer.

http://www.wikidata.org/entity/Q33747803

description

2010 nî lūn-bûn

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2010 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած

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2010 թվականի նոյեմբերին հրատարակված գիտական հոդված

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2010年の論文

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2010年論文

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2010年論文

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2010年論文

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2010年論文

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2010年論文

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2010年论文

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name

The structural complexity of the human BORIS gene in gametogenesis and cancer.

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The structural complexity of the human BORIS gene in gametogenesis and cancer.

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type

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The structural complexity of the human BORIS gene in gametogenesis and cancer.

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The structural complexity of the human BORIS gene in gametogenesis and cancer.

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prefLabel

The structural complexity of the human BORIS gene in gametogenesis and cancer.

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The structural complexity of the human BORIS gene in gametogenesis and cancer.

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JOURNAL.PONE.0013872

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The structural complexity of the human BORIS gene in gametogenesis and cancer.

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Alexander A Vostrov

http://www.w3.org/2001/XMLSchema#string

Dmitri Loukinov

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Elena M Pugacheva

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Eugene Barsov

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Jeongheon Yoon

http://www.w3.org/2001/XMLSchema#string

Natsuki Kosaka-Suzuki

http://www.w3.org/2001/XMLSchema#string

Teruhiko Suzuki

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P2860

The testis-specific factor CTCFL cooperates with the protein methyltransferase PRMT7 in H19 imprinting control region methylation

The zinc finger protein CTCF binds to the APBbeta domain of the amyloid beta-protein precursor promoter. Evidence for a role in transcriptional activation

Reciprocal binding of CTCF and BORIS to the NY-ESO-1 promoter coincides with derepression of this cancer-testis gene in lung cancer cells

BORIS, a novel male germ-line-specific protein associated with epigenetic reprogramming events, shares the same 11-zinc-finger domain with CTCF, the insulator protein involved in reading imprinting marks in the soma.

CTCF: master weaver of the genome

BORIS, a paralogue of the transcription factor, CTCF, is aberrantly expressed in breast tumours

Expression of the CTCF-paralogous cancer-testis gene, brother of the regulator of imprinted sites (BORIS), is regulated by three alternative promoters modulated by CpG methylation and by CTCF and p53 transcription factors

High-resolution profiling of histone methylations in the human genome

Methylation of a CTCF-dependent boundary controls imprinted expression of the Igf2 gene

CTCF mediates methylation-sensitive enhancer-blocking activity at the H19/Igf2 locus

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e13872

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scholarly article

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10.1371/JOURNAL.PONE.0013872

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11

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5

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Herbert C. Morse

Victor V Lobanenkov

Svetlana D. Pack

Alexander Strunnikov

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2010-11-08T00:00:00Z

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47795095

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21079786

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2975627

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