Replicating Huntington's disease phenotype in experimental animals.
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The excitatory neurotransmitter glutamate stimulates DNA repair to increase neuronal resiliencyTherapeutic potential of mood stabilizers lithium and valproic acid: beyond bipolar disorderOld Things New View: Ascorbic Acid Protects the Brain in Neurodegenerative DisordersElectron Transport Disturbances and Neurodegeneration: From Albert Szent-Györgyi's Concept (Szeged) till Novel Approaches to Boost Mitochondrial BioenergeticsThe Nrf2-ARE pathway: a valuable therapeutic target for the treatment of neurodegenerative diseasesIron dysregulation in Huntington's diseasePossible involvement of self-defense mechanisms in the preferential vulnerability of the striatum in Huntington's diseaseReactive Oxygen Species: Physiological and Physiopathological Effects on Synaptic PlasticityOrphenadrine prevents 3-nitropropionic acid-induced neurotoxicity in vitro and in vivoA role for oxidized DNA precursors in Huntington's disease-like striatal neurodegenerationMutant huntingtin alters cell fate in response to microtubule depolymerization via the GEF-H1-RhoA-ERK pathwayHigh-throughput screening in primary neuronsCoenzyme Q protects Caenorhabditis elegans GABA neurons from calcium-dependent degeneration.High throughput screening for neurodegeneration and complex disease phenotypes.Normal aging modulates the neurotoxicity of mutant huntingtin.Protection from mitochondrial complex II inhibition in vitro and in vivo by Nrf2-mediated transcription.Ciliary neurotrophic factor protects striatal neurons against excitotoxicity by enhancing glial glutamate uptake.Fatty acids in energy metabolism of the central nervous systemGeldanamycin attenuates 3‑nitropropionic acid‑induced apoptosis and JNK activation through the expression of HSP 70 in striatal cells.Effects of intracellular expression of anti-huntingtin antibodies of various specificities on mutant huntingtin aggregation and toxicityMitochondrial reactive oxygen species (ROS) and ROS-induced ROS release.Tauroursodeoxycholic acid, a bile acid, is neuroprotective in a transgenic animal model of Huntington's disease.The selective vulnerability of nerve cells in Huntington's disease.Neuroprotective possibilities for Huntington's disease.Involvement of mitochondrial complex II defects in neuronal death produced by N-terminus fragment of mutated huntingtinDelayed Onset and Reduced Cognitive Deficits through Pre-Conditioning with 3-Nitropropionic Acid is Dependent on Sex and CAG Repeat Length in the R6/2 Mouse Model of Huntington's Disease.Differential electrophysiological changes in striatal output neurons in Huntington's disease.A chemical compound commonly used to inhibit PKR, {8-(imidazol-4-ylmethylene)-6H-azolidino[5,4-g] benzothiazol-7-one}, protects neurons by inhibiting cyclin-dependent kinase.Antioxidants as treatment for neurodegenerative disorders.The Nrf2-ARE cytoprotective pathway in astrocytes.Mitogen- and stress-activated protein kinase 1-induced neuroprotection in Huntington's disease: role on chromatin remodeling at the PGC-1-alpha promoter.Altered Balance of Activity in the Striatal Direct and Indirect Pathways in Mouse Models of Huntington's DiseaseClinical and research advances in Huntington's disease.GSK-3 as a Target for Lithium-Induced Neuroprotection Against Excitotoxicity in Neuronal Cultures and Animal Models of Ischemic Stroke.Molecular actions and therapeutic potential of lithium in preclinical and clinical studies of CNS disordersNeuroprotective action of lithium in disorders of the central nervous system.Huntington's Disease and Striatal Signaling.Role of LOX/COX pathways in 3-nitropropionic acid-induced Huntington's disease-like symptoms in rats: protective effect of licofelone.Progressive cognitive deficit, motor impairment and striatal pathology in a transgenic Huntington disease monkey model from infancy to adulthood.Cardiac dysfunction in the R6/2 mouse model of Huntington's disease
P2860
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P2860
Replicating Huntington's disease phenotype in experimental animals.
description
1999 nî lūn-bûn
@nan
1999 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
1999 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
1999年の論文
@ja
1999年論文
@yue
1999年論文
@zh-hant
1999年論文
@zh-hk
1999年論文
@zh-mo
1999年論文
@zh-tw
1999年论文
@wuu
name
Replicating Huntington's disease phenotype in experimental animals.
@ast
Replicating Huntington's disease phenotype in experimental animals.
@en
type
label
Replicating Huntington's disease phenotype in experimental animals.
@ast
Replicating Huntington's disease phenotype in experimental animals.
@en
prefLabel
Replicating Huntington's disease phenotype in experimental animals.
@ast
Replicating Huntington's disease phenotype in experimental animals.
@en
P2093
P1476
Replicating Huntington's disease phenotype in experimental animals.
@en
P2093
P304
P356
10.1016/S0301-0082(99)00005-2
P577
1999-12-01T00:00:00Z