Susceptibility of Plasmodium falciparum to a combination of thymidine and ICI D1694, a quinazoline antifolate directed at thymidylate synthase.
about
Plasmodium dihydroorotate dehydrogenase: a promising target for novel anti-malarial chemotherapy.Potent and selective activity of a combination of thymidine and 1843U89, a folate-based thymidylate synthase inhibitor, against Plasmodium falciparum.Frequency of drug resistance in Plasmodium falciparum: a nonsynergistic combination of 5-fluoroorotate and atovaquone suppresses in vitro resistance.Kinetics of Plasmodium falciparum thymidylate synthase: interactions with high-affinity metabolites of 5-fluoroorotate and D1694Comparative folate metabolism in humans and malaria parasites (part I): pointers for malaria treatment from cancer chemotherapy.Antimalarial drugs - host targets (re)visited.Malaria chemotherapeutics part I: History of antimalarial drug development, currently used therapeutics, and drugs in clinical development.Triazolopyrimidine-based dihydroorotate dehydrogenase inhibitors with potent and selective activity against the malaria parasite Plasmodium falciparum.Essential protein-protein interactions between Plasmodium falciparum thymidylate synthase and dihydrofolate reductase domains.Chemical and genetic validation of dihydrofolate reductase-thymidylate synthase as a drug target in African trypanosomes.Malarial dihydroorotate dehydrogenase. Substrate and inhibitor specificity.Formation of catalytically active cross-species heterodimers of thymidylate synthase from Plasmodium falciparum and Plasmodium vivax.
P2860
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P2860
Susceptibility of Plasmodium falciparum to a combination of thymidine and ICI D1694, a quinazoline antifolate directed at thymidylate synthase.
description
1994 nî lūn-bûn
@nan
1994 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
1994 թվականի մարտին հրատարակված գիտական հոդված
@hy
1994年の論文
@ja
1994年論文
@yue
1994年論文
@zh-hant
1994年論文
@zh-hk
1994年論文
@zh-mo
1994年論文
@zh-tw
1994年论文
@wuu
name
Susceptibility of Plasmodium f ...... ected at thymidylate synthase.
@ast
Susceptibility of Plasmodium f ...... ected at thymidylate synthase.
@en
type
label
Susceptibility of Plasmodium f ...... ected at thymidylate synthase.
@ast
Susceptibility of Plasmodium f ...... ected at thymidylate synthase.
@en
prefLabel
Susceptibility of Plasmodium f ...... ected at thymidylate synthase.
@ast
Susceptibility of Plasmodium f ...... ected at thymidylate synthase.
@en
P2860
P356
P1476
Susceptibility of Plasmodium f ...... ected at thymidylate synthase.
@en
P2093
P2860
P304
P356
10.1128/AAC.38.3.476
P407
P577
1994-03-01T00:00:00Z