ApoE4 decreases spine density and dendritic complexity in cortical neurons in vivo. - Test2 - elhamkhani - TriplyDB

ApoE4 decreases spine density and dendritic complexity in cortical neurons in vivo.

ApoE4 decreases spine density and dendritic complexity in cortical neurons in vivo.

http://www.wikidata.org/entity/Q33758196

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Alzheimer mechanisms and therapeutic strategies Arf4 determines dentate gyrus-mediated pattern separation by regulating dendritic spine development Gene transfer of human Apoe isoforms results in differential modulation of amyloid deposition and neurotoxicity in mouse brain ApoE4 delays dendritic spine formation during neuron development and accelerates loss of mature spines in vitro Apolipoprotein E isoforms and regulation of the innate immune response in brain of patients with Alzheimer's disease Apolipoprotein E and apolipoprotein E receptors: normal biology and roles in Alzheimer disease The dendritic hypothesis for Alzheimer's disease pathophysiology.Apolipoprotein E and Alzheimer disease: risk, mechanisms and therapy Reduced hippocampal volume in healthy young ApoE4 carriers: an MRI study Dendritic spine pathology in neuropsychiatric disorders Tracking pathophysiological processes in Alzheimer's disease: an updated hypothetical model of dynamic biomarkers Gene sequences regulating the production of apoE and cerebral palsy of variable severity.Differential splicing and glycosylation of Apoer2 alters synaptic plasticity and fear learning Apolipoprotein E polymorphisms and severity of cerebral palsy: a cross-sectional study in 255 children in Norway.Impact of apolipoprotein E ε4 and HIV on cognition and brain atrophy: antagonistic pleiotropy and premature brain aging.Structure-dependent impairment of intracellular apolipoprotein E4 trafficking and its detrimental effects are rescued by small-molecule structure correctors ApoE4 induces Aβ42, tau, and neuronal pathology in the hippocampus of young targeted replacement apoE4 mice.Opposing effects of Apoe/Apoa1 double deletion on amyloid-β pathology and cognitive performance in APP mice.Low-doses of cisplatin injure hippocampal synapses: a mechanism for 'chemo' brain?APOE and neuroenergetics: an emerging paradigm in Alzheimer's disease.Progressive loss of synaptic integrity in human apolipoprotein E4 targeted replacement mice and attenuation by apolipoprotein E2.Spatial memory deficits in a mouse model of late-onset Alzheimer's disease are caused by zinc supplementation and correlate with amyloid-beta levels ApoE receptor 2 regulates synapse and dendritic spine formation Altered neurotransmission in the lateral amygdala in aged human apoE4 targeted replacement mice.Apolipoprotein E: structure and function in lipid metabolism, neurobiology, and Alzheimer's diseases.Apolipoprotein E in synaptic plasticity and Alzheimer's disease: potential cellular and molecular mechanisms.Cellular source-specific effects of apolipoprotein (apo) E4 on dendrite arborization and dendritic spine development.CNF1 increases brain energy level, counteracts neuroinflammatory markers and rescues cognitive deficits in a murine model of Alzheimer's disease.Apolipoprotein E, gender, and Alzheimer's disease: an overlooked, but potent and promising interaction Transgenic animal models of neurodegeneration based on human genetic studies.Impaired regulation of synaptic actin cytoskeleton in Alzheimer's disease.Regional-specific effects of ovarian hormone loss on synaptic plasticity in adult human APOE targeted replacement mice.APOE4 enhances age-dependent decline in cognitive function by down-regulating an NMDA receptor pathway in EFAD-Tg mice.Introducing Human APOE into Aβ Transgenic Mouse Models.A combined effect of two Alzheimer's risk genes on medial temporal activity during executive attention in young adults.Presence of ApoE ε4 allele associated with thinner frontal cortex in middle age.Rapid estradiol modulation of neuronal connectivity and its implications for disease.Bexarotene-Activated Retinoid X Receptors Regulate Neuronal Differentiation and Dendritic Complexity.Apolipoprotein E level and cholesterol are associated with reduced synaptic amyloid beta in Alzheimer's disease and apoE TR mouse cortex APOE genotype affects the pre-synaptic compartment of glutamatergic nerve terminals

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P2860

ApoE4 decreases spine density and dendritic complexity in cortical neurons in vivo.

http://www.wikidata.org/entity/Q33758196

description

2009 nî lūn-bûn

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2009 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած

@hyw

2009 թվականի դեկտեմբերին հրատարակված գիտական հոդված

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2009年の論文

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2009年学术文章

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2009年学术文章

@zh-cn

2009年学术文章

@zh-hans

2009年学术文章

@zh-my

2009年学术文章

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2009年學術文章

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name

ApoE4 decreases spine density and dendritic complexity in cortical neurons in vivo.

@ast

ApoE4 decreases spine density and dendritic complexity in cortical neurons in vivo.

@en

type

label

ApoE4 decreases spine density and dendritic complexity in cortical neurons in vivo.

@ast

ApoE4 decreases spine density and dendritic complexity in cortical neurons in vivo.

@en

prefLabel

ApoE4 decreases spine density and dendritic complexity in cortical neurons in vivo.

@ast

ApoE4 decreases spine density and dendritic complexity in cortical neurons in vivo.

@en

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JNEUROSCI.4026-09.2009

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Journal of Neuroscience

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ApoE4 decreases spine density and dendritic complexity in cortical neurons in vivo

@en

P2093

Baoji Xu

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Edwin J Weeber

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G William Rebeck

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Hyang-Sook Hoe

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Joseph A Tesoriero

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Justin H Trotter

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Lenard W Babus

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Madeline T Nguyen

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Sonya B Dumanis

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P2860

Apolipoprotein E: high-avidity binding to beta-amyloid and increased frequency of type 4 allele in late-onset familial Alzheimer disease

Rosiglitazone increases dendritic spine density and rescues spine loss caused by apolipoprotein E4 in primary cortical neurons

Interaction of reelin with amyloid precursor protein promotes neurite outgrowth

A fresh look at an ancient receptor family: emerging roles for low density lipoprotein receptors in synaptic plasticity and memory formation

Regulation of dendritic spine morphology by SPAR, a PSD-95-associated RapGAP

Stable expression and secretion of apolipoproteins E3 and E4 in mouse neuroblastoma cells produces differential effects on neurite outgrowth

Distinct patterns of brain activity in young carriers of the APOE-epsilon4 allele

Apolipoprotein E receptors: linking brain development and Alzheimer's disease.

APOE related alterations in cerebral activation even at college age.

ApoE isoform-dependent changes in hippocampal synaptic function

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15317-15322

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