Targeted disruption of Tgif, the mouse ortholog of a human holoprosencephaly gene, does not result in holoprosencephaly in mice.
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Tgif1 and Tgif2 regulate Nodal signaling and are required for gastrulation.Functional analysis of mutations in TGIF associated with holoprosencephaly.TALE transcription factors during early development of the vertebrate brain and eyeTGIF governs a feed-forward network that empowers Wnt signaling to drive mammary tumorigenesisEmbryonic fibroblasts from mice lacking Tgif were defective in cell cyclingPremature senescence and increased TGFβ signaling in the absence of Tgif1.TGIF inhibits retinoid signalingTgif1 and Tgif2 Repress Expression of the RabGAP Evi5l.Genetic and Molecular Analyses indicate independent effects of TGIFs on Nodal and Gli3 in neural tube patterning.Tgif1 and Tgif2 Regulate Axial Patterning in Mouse.Loss of Tgif function causes holoprosencephaly by disrupting the SHH signaling pathway.Maternal Tgif is required for vascularization of the embryonic placentaOtitis media in the Tgif knockout mouse implicates TGFβ signalling in chronic middle ear inflammatory disease.Sub-circuits of a gene regulatory network control a developmental epithelial-mesenchymal transitionA multi-resource data integration approach: identification of candidate genes regulating cell proliferation during neocortical development.Holoprosencephaly.The molecular genetics of holoprosencephaly.Retinal regeneration in adult zebrafish requires regulation of TGFβ signaling.Differential roles of TGIF family genes in mammalian reproduction.The extended TILAR approach: a novel tool for dynamic modeling of the transcription factor network regulating the adaption to in vitro cultivation of murine hepatocytes.Targeted ablation of the Pde6h gene in mice reveals cross-species differences in cone and rod phototransduction protein isoform inventory.Pathogenesis of holoprosencephalyREST corepressors RCOR1 and RCOR2 and the repressor INSM1 regulate the proliferation-differentiation balance in the developing brain.Glimpse into Hox and tale regulation of cell differentiation and reprogramming.Discovering sparse transcription factor codes for cell states and state transitions during developmentZebrafish model of holoprosencephaly demonstrates a key role for TGIF in regulating retinoic acid metabolism.Functions of TGIF homeodomain proteins and their roles in normal brain development and holoprosencephaly
P2860
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P2860
Targeted disruption of Tgif, the mouse ortholog of a human holoprosencephaly gene, does not result in holoprosencephaly in mice.
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2005 nî lūn-bûn
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2005 թուականի Մայիսին հրատարակուած գիտական յօդուած
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2005年の論文
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2005年学术文章
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Targeted disruption of Tgif, t ...... in holoprosencephaly in mice.
@ast
Targeted disruption of Tgif, t ...... in holoprosencephaly in mice.
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type
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Targeted disruption of Tgif, t ...... in holoprosencephaly in mice.
@ast
Targeted disruption of Tgif, t ...... in holoprosencephaly in mice.
@en
prefLabel
Targeted disruption of Tgif, t ...... in holoprosencephaly in mice.
@ast
Targeted disruption of Tgif, t ...... in holoprosencephaly in mice.
@en
P2860
P1476
Targeted disruption of Tgif, t ...... in holoprosencephaly in mice.
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P2093
Christopher A Walsh
P2860
P304
P356
10.1128/MCB.25.9.3639-3647.2005
P407
P577
2005-05-01T00:00:00Z