The formulated microbicide RC-101 was safe and antivirally active following intravaginal application in pigtailed macaques - Test2 - elhamkhani - TriplyDB

The formulated microbicide RC-101 was safe and antivirally active following intravaginal application in pigtailed macaques

The formulated microbicide RC-101 was safe and antivirally active following intravaginal application in pigtailed macaques

http://www.wikidata.org/entity/Q33760642

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The Role of Cationic Polypeptides in Modulating HIV-1 Infection of the Cervicovaginal Mucosa Drug transporters in tissues and cells relevant to sexual transmission of HIV: Implications for drug delivery Mechanisms and modifications of naturally occurring host defense peptides for anti-HIV microbicide development A compensatory mutation provides resistance to disparate HIV fusion inhibitor peptides and enhances membrane fusion Drivers of Vaginal Drug Delivery System Acceptability from Internet-Based Conjoint Analysis Formulation, pharmacokinetics and pharmacodynamics of topical microbicides.Prophylactic and therapeutic effect of AZT/3TC in RT-SHIV infected Chinese-origin rhesus macaques Historical development of vaginal microbicides to prevent sexual transmission of HIV in women: from past failures to future hopes.Release of tenofovir from carrageenan-based vaginal suppositories.Firmness Perception Influences Women's Preferences for Vaginal Suppositories.Formulation development of retrocyclin 1 analog RC-101 as an anti-HIV vaginal microbicide product.Formulation and characterization of polymeric films containing combinations of antiretrovirals (ARVs) for HIV prevention Topical prophylaxis for HIV prevention in women: becoming a reality.Non-specific microbicide product development: then and now Characterization of the retrocyclin analogue RC-101 as a preventative of Staphylococcus aureus nasal colonization Simultaneous delivery of tenofovir and acyclovir via an intravaginal ring Retrocyclins and their activity against HIV-1.Assessing the potential of the Woman's Condom for vaginal drug delivery Retrocyclin RC-101 blocks HIV-1 transmission across cervical mucosa in an organ culture.An intravaginal ring for the sustained delivery of tenofovir disoproxil fumarate.Longitudinal assessment of pigtailed macaque lower genital tract microbiota by pyrosequencing reveals dissimilarity to the genital microbiota of healthy humans The anti-HIV microbicide candidate RC-101 inhibits pathogenic vaginal bacteria without harming endogenous flora or mucosa.Antiviral activity of retrocyclin RC-101, a candidate microbicide against cell-associated HIV-1 Safety and Pharmacokinetics of Quick-Dissolving Polymeric Vaginal Films Delivering the Antiretroviral IQP-0528 for Preexposure Prophylaxis.Cationic host defence peptides: potential as antiviral therapeutics Peptides as the next generation of anti-infectives.Activation of human mast cells by retrocyclin and protegrin highlight their immunomodulatory and antimicrobial properties.The Role of Defensins in HIV Pathogenesis.Innovative sensory methods to access acceptability of mixed polymer semisoft ovules for microbicide applications.θ-Defensins: cyclic peptides with endless potential.

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P2860

The formulated microbicide RC-101 was safe and antivirally active following intravaginal application in pigtailed macaques

http://www.wikidata.org/entity/Q33760642

description

2010 nî lūn-bûn

@nan

2010 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած

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2010 թվականի նոյեմբերին հրատարակված գիտական հոդված

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2010年の論文

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2010年論文

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2010年論文

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2010年論文

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2010年論文

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2010年論文

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2010年论文

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The formulated microbicide RC- ...... lication in pigtailed macaques

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Alan J Waring

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Alexander M Cole

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Alexandra B Sassi

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Amy L Cole

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Bharat Ramratnam

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Carol Lackman-Smith

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Deena Ratner

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Dorothy L Patton

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Lisa C Rohan

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Nicole A Rogers

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P2860

Identification of gammaretroviruses constitutively released from cell lines used for human immunodeficiency virus research

The role of mononuclear phagocytes in HTLV-III/LAV infection

Emergence of resistant human immunodeficiency virus type 1 in patients receiving fusion inhibitor (T-20) monotherapy.

Effects of CCR5 and CD4 cell surface concentrations on infections by macrophagetropic isolates of human immunodeficiency virus type 1.

A cyclic antimicrobial peptide produced in primate leukocytes by the ligation of two truncated alpha-defensins.

The theta-defensin, retrocyclin, inhibits HIV-1 entry.

Retrocyclin: a primate peptide that protects cells from infection by T- and M-tropic strains of HIV-1.

A summary of preclinical topical microbicide vaginal safety and chlamydial efficacy evaluations in a pigtailed macaque model.

Formulation development of retrocyclin 1 analog RC-101 as an anti-HIV vaginal microbicide product.

Relationship of vaginal bacteria and inflammation with conception and early pregnancy loss following in-vitro fertilization

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