Genome-wide analysis of histone modifications in human pancreatic islets.
about
Predicting cell types and genetic variations contributing to disease by combining GWAS and epigenetic dataIntegrated genetic and epigenetic analysis identifies haplotype-specific methylation in the FTO type 2 diabetes and obesity susceptibility locusThe role of epigenetics in the pathology of diabetic complicationsBrd2 gene disruption causes "metabolically healthy" obesity: epigenetic and chromatin-based mechanisms that uncouple obesity from type 2 diabetesTranscriptional and epigenetic regulation in human isletsTranslational implications of the β-cell epigenome in diabetes mellitusEpigenome-Wide Association Studies (EWAS) in CancerEpigenomic plasticity enables human pancreatic α to β cell reprogramming.The Pancreatic Islet Regulome Browser.β-cell failure in type 2 diabetes: postulated mechanisms and prospects for prevention and treatment.Increased DNA methylation and decreased expression of PDX-1 in pancreatic islets from patients with type 2 diabetes.Discovering cooperative relationships of chromatin modifications in human T cells based on a proposed closeness measureDetection of type 2 diabetes related modules and genes based on epigenetic networksTight associations between transcription promoter type and epigenetic variation in histone positioning and modification.PBX1 genomic pioneer function drives ERα signaling underlying progression in breast cancer.Evidence for sequence biases associated with patterns of histone methylation.Pancreatic islet enhancer clusters enriched in type 2 diabetes risk-associated variants.The pancreatic β cell: recent insights from human genetics.Tissue-specific regulation of mouse microRNA genes in endoderm-derived tissuesGlobal epigenomic analysis of primary human pancreatic islets provides insights into type 2 diabetes susceptibility loci.Novel pancreatic endocrine maturation pathways identified by genomic profiling and causal reasoning.The genomic signature of trait-associated variants.Genetic associations of type 2 diabetes with islet amyloid polypeptide processing and degrading pathways in asian populationsRegulatory and coding genome regions are enriched for trait associated variants in dairy and beef cattle.Stem cell approaches for diabetes: towards beta cell replacement.Global analysis of H3K4me3 and H3K27me3 profiles in glioblastoma stem cells and identification of SLC17A7 as a bivalent tumor suppressor gene.DNA methylation profiling identifies epigenetic dysregulation in pancreatic islets from type 2 diabetic patients.Organogenesis and functional genomics of the endocrine pancreasTranscriptional Regulation of the Pancreatic Islet: Implications for Islet Function.O-Linked β-N-acetylglucosamine (O-GlcNAc) Acts as a Glucose Sensor to Epigenetically Regulate the Insulin Gene in Pancreatic Beta Cells.NRSF and BDNF polymorphisms as biomarkers of cognitive dysfunction in adults with newly diagnosed epilepsyDynamic chromatin remodeling mediated by polycomb proteins orchestrates pancreatic differentiation of human embryonic stem cells.Epigenetic modifications in the pathogenesis of diabetic nephropathyNeonatal monocytes exhibit a unique histone modification landscape.Mapping human epigenomes.Dominant form of congenital hyperinsulinism maps to HK1 region on 10q.Functional annotation of sixty-five type-2 diabetes risk SNPs and its application in risk predictionNutrients and the Pancreas: An Epigenetic Perspective.The epigenomic interface between genome and environment in common complex diseases.Developmental plasticity and epigenetic mechanisms underpinning metabolic and cardiovascular diseases.
P2860
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P2860
Genome-wide analysis of histone modifications in human pancreatic islets.
description
2010 nî lūn-bûn
@nan
2010 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Genome-wide analysis of histone modifications in human pancreatic islets.
@ast
Genome-wide analysis of histone modifications in human pancreatic islets.
@en
type
label
Genome-wide analysis of histone modifications in human pancreatic islets.
@ast
Genome-wide analysis of histone modifications in human pancreatic islets.
@en
prefLabel
Genome-wide analysis of histone modifications in human pancreatic islets.
@ast
Genome-wide analysis of histone modifications in human pancreatic islets.
@en
P2093
P2860
P356
P1433
P1476
Genome-wide analysis of histone modifications in human pancreatic islets.
@en
P2093
Chengyang Liu
John Le Lay
Jonathan Schug
Klaus H Kaestner
Olga Smirnova
Reena Bhandare
P2860
P304
P356
10.1101/GR.102038.109
P577
2010-02-24T00:00:00Z