Sequence homologies, N sequence insertion and JH gene utilization in VHDJH joining: implications for the joining mechanism and the ontogenetic timing of Ly1 B cell and B-CLL progenitor generation
about
The characterization of a mammalian DNA structure-specific endonucleaseSite-specific translocation and evidence of postnatal origin of the t(1;19) E2A-PBX1 fusion in childhood acute lymphoblastic leukemia.Human B1 cells in umbilical cord and adult peripheral blood express the novel phenotype CD20+ CD27+ CD43+ CD70-A critical role of natural immunoglobulin M in immediate defense against systemic bacterial infectionClonally-related immunoglobulin VH domains and nonrandom use of DH gene segments in rheumatoid arthritis synoviumNatural Antibodies as Rheostats for Susceptibility to Chronic Diseases in the AgedMechanistic constraints on diversity in human V(D)J recombinationDifferential splicing in mouse thymus generates two forms of terminal deoxynucleotidyl transferaseNormal induction but attenuated progression of germinal center responses in BAFF and BAFF-R signaling-deficient miceRemarkably similar antigen receptors among a subset of patients with chronic lymphocytic leukemiaMost peripheral B cells in mice are ligand selected.The ontogeny of diversification at the immunoglobulin heavy chain locus in Xenopus.Ordering human CD34+CD10-CD19+ pre/pro-B-cell and CD19- common lymphoid progenitor stages in two pro-B-cell development pathways.Antibody repertoire deep sequencing reveals antigen-independent selection in maturing B cellsBone marrow cells in X-linked agammaglobulinemia express pre-B-specific genes (lambda-like and V pre-B) and present immunoglobulin V-D-J gene usage strongly biased to a fetal-like repertoire.Enumeration and characterization of DJH structures in mouse fetal liver.High-resolution description of antibody heavy-chain repertoires in humans.Gene targeting in the Ig kappa locus: efficient generation of lambda chain-expressing B cells, independent of gene rearrangements in Ig kappaChromosomal aberrations induced by double strand DNA breaks.Evidence that the V kappa III gene usage is nonstochastic in both adult and newborn peripheral B cells and that peripheral CD5+ adult B cells are oligoclonal.IgBLAST: an immunoglobulin variable domain sequence analysis toolThe molecular mechanism underlying formation of deletions in Fanconi anemia cells may involve a site-specific recombinationB cell receptors in TCL1 transgenic mice resemble those of aggressive, treatment-resistant human chronic lymphocytic leukemiaKu80 is required for addition of N nucleotides to V(D)J recombination junctions by terminal deoxynucleotidyl transferaseViolation of an evolutionarily conserved immunoglobulin diversity gene sequence preference promotes production of dsDNA-specific IgG antibodies.Monoclonal immunoglobulin A derived from peritoneal B cells is encoded by both germ line and somatically mutated VH genes and is reactive with commensal bacteriaForced usage of positively charged amino acids in immunoglobulin CDR-H3 impairs B cell development and antibody production.Immunoglobulin light chain variable region gene sequences for human antibodies to Haemophilus influenzae type b capsular polysaccharide are dominated by a limited number of V kappa and V lambda segments and VJ combinations.Characterization of the immunoglobulin heavy chain complementarity determining region (CDR)-III sequences from human B cell precursor acute lymphoblastic leukemia cells.Human B-1 cells take the stage.The genomic organization of immunoglobulin VH genes in Xenopus laevis shows evidence for interspersion of familiesA mechanistic basis for Mre11-directed DNA joining at microhomologies.A CD25⁻ positive population of activated B1 cells expresses LIFR and responds to LIFA Comprehensive Analysis of the Phylogeny, Genomic Organization and Expression of Immunoglobulin Light Chain Genes in Alligator sinensis, an Endangered Reptile Species.A special repertoire of alpha:beta T cells in neonatal mice.Junctional sequences of fetal T cell receptor beta chains have few N regions.The junctional modifications of a T cell receptor gamma chain are determined at the level of thymic precursorsEvidence for somatic selection of natural autoantibodies.Natural occurrence and origin of somatically mutated memory B cells in miceN region diversity of a transgenic substrate in fetal and adult lymphoid cells
P2860
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P2860
Sequence homologies, N sequence insertion and JH gene utilization in VHDJH joining: implications for the joining mechanism and the ontogenetic timing of Ly1 B cell and B-CLL progenitor generation
description
1990 nî lūn-bûn
@nan
1990 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
1990 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
1990年の論文
@ja
1990年論文
@yue
1990年論文
@zh-hant
1990年論文
@zh-hk
1990年論文
@zh-mo
1990年論文
@zh-tw
1990年论文
@wuu
name
Sequence homologies, N sequenc ...... nd B-CLL progenitor generation
@ast
Sequence homologies, N sequenc ...... nd B-CLL progenitor generation
@en
type
label
Sequence homologies, N sequenc ...... nd B-CLL progenitor generation
@ast
Sequence homologies, N sequenc ...... nd B-CLL progenitor generation
@en
prefLabel
Sequence homologies, N sequenc ...... nd B-CLL progenitor generation
@ast
Sequence homologies, N sequenc ...... nd B-CLL progenitor generation
@en
P2093
P2860
P1433
P1476
Sequence homologies, N sequenc ...... nd B-CLL progenitor generation
@en
P2093
P2860
P304
P356
10.1002/J.1460-2075.1990.TB07382.X
P407
P577
1990-07-01T00:00:00Z