Six Rossmannoid folds, including the Class I aminoacyl-tRNA synthetases, share a partial core with the anti-codon-binding domain of a Class II aminoacyl-tRNA synthetase.
about
Urzymology: experimental access to a key transition in the appearance of enzymesFunctional Class I and II Amino Acid-activating Enzymes Can Be Coded by Opposite Strands of the Same GeneThe Rodin-Ohno hypothesis that two enzyme superfamilies descended from one ancestral gene: an unlikely scenario for the origins of translation that will not be dismissed.High-Dimensional Mutant and Modular Thermodynamic Cycles, Molecular Switching, and Free Energy Transduction.Tryptophanyl-tRNA synthetase Urzyme: a model to recapitulate molecular evolution and investigate intramolecular complementationStatistical evaluation of the Rodin-Ohno hypothesis: sense/antisense coding of ancestral class I and II aminoacyl-tRNA synthetases.Aminoacylating urzymes challenge the RNA world hypothesisFull implementation of the genetic code by tryptophanyl-tRNA synthetase requires intermodular couplingEnhanced amino acid selection in fully evolved tryptophanyl-tRNA synthetase, relative to its urzyme, requires domain motion sensed by the D1 switch, a remote dynamic packing motif.Combining multi-mutant and modular thermodynamic cycles to measure energetic coupling networks in enzyme catalysis.Towards functional repertoire of the earliest proteins.A master switch couples Mg²⁺-assisted catalysis to domain motion in B. stearothermophilus tryptophanyl-tRNA SynthetaseInterdependence, Reflexivity, Fidelity, Impedance Matching, and the Evolution of Genetic Coding.Coding of Class I and II Aminoacyl-tRNA Synthetases.Mechanism of the activation step of the aminoacylation reaction: a significant difference between class I and class II synthetases.Predictions of protein-RNA interactions
P2860
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P2860
Six Rossmannoid folds, including the Class I aminoacyl-tRNA synthetases, share a partial core with the anti-codon-binding domain of a Class II aminoacyl-tRNA synthetase.
description
2010 nî lūn-bûn
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2010 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2010年の論文
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2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
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2010年论文
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name
Six Rossmannoid folds, includi ...... II aminoacyl-tRNA synthetase.
@ast
Six Rossmannoid folds, includi ...... II aminoacyl-tRNA synthetase.
@en
type
label
Six Rossmannoid folds, includi ...... II aminoacyl-tRNA synthetase.
@ast
Six Rossmannoid folds, includi ...... II aminoacyl-tRNA synthetase.
@en
prefLabel
Six Rossmannoid folds, includi ...... II aminoacyl-tRNA synthetase.
@ast
Six Rossmannoid folds, includi ...... II aminoacyl-tRNA synthetase.
@en
P2860
P356
P1433
P1476
Six Rossmannoid folds, includi ...... II aminoacyl-tRNA synthetase.
@en
P2093
Charles W Carter
Stephen Cammer
P2860
P304
P356
10.1093/BIOINFORMATICS/BTQ039
P407
P577
2010-02-03T00:00:00Z