Matefin, a Caenorhabditis elegans germ line-specific SUN-domain nuclear membrane protein, is essential for early embryonic and germ cell development. - Test2 - elhamkhani - TriplyDB

Matefin, a Caenorhabditis elegans germ line-specific SUN-domain nuclear membrane protein, is essential for early embryonic and germ cell development.

Matefin, a Caenorhabditis elegans germ line-specific SUN-domain nuclear membrane protein, is essential for early embryonic and germ cell development.

http://www.wikidata.org/entity/Q33782014

about

LINC complexes form by binding of three KASH peptides to domain interfaces of trimeric SUN proteins Chromosome movement in meiosis I prophase of Caenorhabditis elegans Structure of Sad1-UNC84 Homology (SUN) Domain Defines Features of Molecular Bridge in Nuclear Envelope MPS3 mediates meiotic bouquet formation in Saccharomyces cerevisiae.Inner/Outer nuclear membrane fusion in nuclear pore assembly: biochemical demonstration and molecular analysis SUN1/2 and Syne/Nesprin-1/2 complexes connect centrosome to the nucleus during neurogenesis and neuronal migration in mice Transmembrane protein Sun2 is involved in tethering mammalian meiotic telomeres to the nuclear envelope Barrier to autointegration factor blocks premature cell fusion and maintains adult muscle integrity in C. elegans.Centrosome attachment to the C. elegans male pronucleus is dependent on the surface area of the nuclear envelope.KDP-1 is a nuclear envelope KASH protein required for cell-cycle progression The SUN protein UNC-84 is required only in force-bearing cells to maintain nuclear envelope architecture.Cytoskeletal forces span the nuclear envelope to coordinate meiotic chromosome pairing and synapsis.Interactions between nuclei and the cytoskeleton are mediated by SUN-KASH nuclear-envelope bridges.Structural insights into LINC complexes.Barrier-to-autointegration factor is required to segregate and enclose chromosomes within the nuclear envelope and assemble the nuclear lamina The Caenorhabditis elegans SUN protein UNC-84 interacts with lamin to transfer forces from the cytoplasm to the nucleoskeleton during nuclear migration.Nuclear envelope localization of human UNC84A does not require nuclear lamins.SUN1 interacts with nuclear lamin A and cytoplasmic nesprins to provide a physical connection between the nuclear lamina and the cytoskeleton Matefin/SUN-1 is a nuclear envelope receptor for CED-4 during Caenorhabditis elegans apoptosis.Pairing centers recruit a Polo-like kinase to orchestrate meiotic chromosome dynamics in C. elegans.Ce-emerin and LEM-2: essential roles in Caenorhabditis elegans development, muscle function, and mitosis.Nuclear mechanics in cancer Laminopathic mutations interfere with the assembly, localization, and dynamics of nuclear lamins.Matefin/SUN-1 Phosphorylation on Serine 43 Is Mediated by CDK-1 and Required for Its Localization to Centrosomes and Normal Mitosis in C. elegans Embryos.Gene silencing at the nuclear periphery.Nuclear Envelope Retention of LINC Complexes Is Promoted by SUN-1 Oligomerization in the Caenorhabditis elegans Germ Line.SUN1 and SUN2 play critical but partially redundant roles in anchoring nuclei in skeletal muscle cells in mice.A nuclear-envelope bridge positions nuclei and moves chromosomes Bringing KASH under the SUN: the many faces of nucleo-cytoskeletal connections.SUN-1 and ZYG-12, mediators of centrosome-nucleus attachment, are a functional SUN/KASH pair in Caenorhabditis elegans.TAN lines: a novel nuclear envelope structure involved in nuclear positioning.Protein interactions at the higher plant nuclear envelope: evidence for a linker of nucleoskeleton and cytoskeleton complex.SUN proteins and nuclear envelope spacing Implications for Diverse Functions of the LINC Complexes Based on the Structure.Essential role for SUN5 in anchoring sperm head to the tail.The B-type cyclin CYB-1 maintains the proper position and number of centrosomes during spermatogenesis in Caenorhabditis elegans.Invertebrate models of lamin diseases.Dictyostelium Sun-1 connects the centrosome to chromatin and ensures genome stability.

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Matefin, a Caenorhabditis elegans germ line-specific SUN-domain nuclear membrane protein, is essential for early embryonic and germ cell development.

http://www.wikidata.org/entity/Q33782014

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Matefin, a Caenorhabditis eleg ...... nic and germ cell development.

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Alexandra Fridkin

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Ayelet Margalit

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Erez Mills

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Esther Neufeld

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Katherine L Wilson

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Merav Cohen

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Naomi Feinstein

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Yosef Gruenbaum

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P2860

UNC-84 localizes to the nuclear envelope and is required for nuclear migration and anchoring during C. elegans development

Nuclear lamins: building blocks of nuclear architecture

Nuclear envelope proteomics: novel integral membrane proteins of the inner nuclear membrane

Barrier-to-autointegration factor (BAF) bridges DNA in a discrete, higher-order nucleoprotein complex

Nuclear membrane proteins with potential disease links found by subtractive proteomics

The C. elegans hook protein, ZYG-12, mediates the essential attachment between the centrosome and nucleus

Specific interference by ingested dsRNA

Creation of low-copy integrated transgenic lines in Caenorhabditis elegans

Transmission electron microscope studies of the nuclear envelope in Caenorhabditis elegans embryos.

ANChors away: an actin based mechanism of nuclear positioning.

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Caenorhabditis elegans

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406453

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