Role of individual T-cell epitopes of Theiler's virus in the pathogenesis of demyelination correlates with the ability to induce a Th1 response.

Role of individual T-cell epitopes of Theiler's virus in the pathogenesis of demyelination correlates with the ability to induce a Th1 response.

Item
http://www.wikidata.org/entity/Q33785859
Theiler's virus infection induces a predominant pathogenic CD4+ T cell response to RNA polymerase in susceptible SJL/J miceDifferential expression of multiple kallikreins in a viral model of multiple sclerosis points to unique roles in the innate and adaptive immune response.Capsid-specific cytotoxic T lymphocytes recognize three distinct H-2D(b)-restricted regions of the BeAn strain of Theiler's virus and exhibit different cytokine profilesThe majority of infiltrating CD8+ T cells in the central nervous system of susceptible SJL/J mice infected with Theiler's virus are virus specific and fully functional.Preferential induction of protective T cell responses to Theiler's virus in resistant (C57BL/6 x SJL)F1 miceInfection with Theiler's murine encephalomyelitis virus directly induces proinflammatory cytokines in primary astrocytes via NF-kappaB activation: potential role for the initiation of demyelinating disease.Genetic deletion of a single immunodominant T-cell response confers susceptibility to virus-induced demyelination.Kallikrein 6 regulates early CNS demyelination in a viral model of multiple sclerosis.Oral administration of live virus protects susceptible mice from developing Theiler's virus-induced demyelinating disease.IL-1 signal affects both protection and pathogenesis of virus-induced chronic CNS demyelinating disease.Differential virus replication, cytokine production, and antigen-presenting function by microglia from susceptible and resistant mice infected with Theiler's virusEpitope-specific CD8+ T cells play a differential pathogenic role in the development of a viral disease model for multiple sclerosisAnticapsid immunity level, not viral persistence level, correlates with the progression of Theiler's virus-induced demyelinating disease in viral P1-transgenic mice.Transgenic expression of non-structural genes of Theiler's virus suppresses initial viral replication and pathogenesis of demyelination.Neuropathogenesis of Theiler's murine encephalomyelitis virus infection, an animal model for multiple sclerosisProstaglandin E2 produced following infection with Theiler's virus promotes the pathogenesis of demyelinating disease.Effects of Keratinocyte-Derived Cytokine (CXCL-1) on the Development of Theiler's Virus-Induced Demyelinating Disease.
P2860

Role of individual T-cell epitopes of Theiler's virus in the pathogenesis of demyelination correlates with the ability to induce a Th1 response.

Item
http://www.wikidata.org/entity/Q33785859
description
1998 nî lūn-bûn
@nan
1998 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
1998 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
1998年の論文
@ja
1998年論文
@yue
1998年論文
@zh-hant
1998年論文
@zh-hk
1998年論文
@zh-mo
1998年論文
@zh-tw
1998年论文
@wuu
name
Role of individual T-cell epit ...... lity to induce a Th1 response.
@ast
Role of individual T-cell epit ...... lity to induce a Th1 response.
@en
type
label
Role of individual T-cell epit ...... lity to induce a Th1 response.
@ast
Role of individual T-cell epit ...... lity to induce a Th1 response.
@en
prefLabel
Role of individual T-cell epit ...... lity to induce a Th1 response.
@ast
Role of individual T-cell epit ...... lity to induce a Th1 response.
@en
P1433
P1476
P2093
P2860
P304
P31
P433
P478
P577
P698
P932
P1433
P1476
Role of individual T-cell epit ...... ility to induce a Th1 response
@en
P2093
P2860
P304
P31
P433
P478
P577
P698
P932