BRCA1, BRCA2 and their possible function in DNA damage response - Test2 - elhamkhani - TriplyDB

BRCA1, BRCA2 and their possible function in DNA damage response

BRCA1, BRCA2 and their possible function in DNA damage response

http://www.wikidata.org/entity/Q33786462

about

Deficiency of human BRCA2 leads to impaired homologous recombination but maintains normal nonhomologous end joining Future possibilities in the prevention of breast cancer: intervention strategies in BRCA1 and BRCA2 mutation carriers.Increased ID4 expression, accompanied by mutant p53 accumulation and loss of BRCA1/2 proteins in triple-negative breast cancer, adversely affects survival.The usefulness of antibodies to the BRCA1 protein in detecting the mutated BRCA1 gene. An immunohistochemical study BRCA2 is a moderate penetrance gene contributing to young-onset prostate cancer: implications for genetic testing in prostate cancer patients.Increased level of chromosomal damage after irradiation of lymphocytes from BRCA1 mutation carriers.The Notch pathway in ovarian carcinomas and adenomas.Mutations of the BRCA1 and BRCA2 genes in patients with bilateral breast cancer.

P2860

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P2860

BRCA1, BRCA2 and their possible function in DNA damage response

http://www.wikidata.org/entity/Q33786462

description

1999 nî lūn-bûn

@nan

1999 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած

@hyw

1999 թվականի դեկտեմբերին հրատարակված գիտական հոդված

@hy

1999年の論文

@ja

1999年論文

@yue

1999年論文

@zh-hant

1999年論文

@zh-hk

1999年論文

@zh-mo

1999年論文

@zh-tw

1999年论文

@wuu

name

BRCA1, BRCA2 and their possible function in DNA damage response

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BRCA1, BRCA2 and their possible function in DNA damage response

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type

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BRCA1, BRCA2 and their possible function in DNA damage response

@ast

BRCA1, BRCA2 and their possible function in DNA damage response

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prefLabel

BRCA1, BRCA2 and their possible function in DNA damage response

@ast

BRCA1, BRCA2 and their possible function in DNA damage response

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P1433

British Journal of Cancer

P1476

BRCA1, BRCA2 and their possible function in DNA damage response

@en

P2093

Eeles RA

http://www.w3.org/2001/XMLSchema#string

P2860

Stable interaction between the products of the BRCA1 and BRCA2 tumor suppressor genes in mitotic and meiotic cells

BRCA2 associates with acetyltransferase activity when bound to P/CAF

The BRC repeats in BRCA2 are critical for RAD51 binding and resistance to methyl methanesulfonate treatment

BRCA1 protein is linked to the RNA polymerase II holoenzyme complex via RNA helicase A

Transcriptional activation functions in BRCA2

BAP1: a novel ubiquitin hydrolase which binds to the BRCA1 RING finger and enhances BRCA1-mediated cell growth suppression

The BRCA2 is a histone acetyltransferase

The BRCA2 gene product functionally interacts with p53 and RAD51

BRCA1 is a component of the RNA polymerase II holoenzyme

A strong candidate for the breast and ovarian cancer susceptibility gene BRCA1

P2888

P304

1099-1102

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scholarly article

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10.1038/SJ.BJC.6690814

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P433

7

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81

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Zsofia Kote-Jarai

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1999-12-01T00:00:00Z

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12716181

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1039904890

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10584867

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P921

transcription factor

breast neoplasm

neoplasm proteins

P932

2374315

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