Foxo1 links homing and survival of naive T cells by regulating L-selectin, CCR7 and interleukin 7 receptor. - Test2 - elhamkhani - TriplyDB

Foxo1 links homing and survival of naive T cells by regulating L-selectin, CCR7 and interleukin 7 receptor.

Foxo1 links homing and survival of naive T cells by regulating L-selectin, CCR7 and interleukin 7 receptor.

http://www.wikidata.org/entity/Q33797113

about

Mst1-FoxO signaling protects Naïve T lymphocytes from cellular oxidative stress in mice Akt and mTOR in B Cell Activation and Differentiation Metabolic regulation of T cell differentiation and function T Cell Adolescence: Maturation Events Beyond Positive Selection Redox regulation of T-cell function: from molecular mechanisms to significance in human health and disease FOXO transcription factors throughout T cell biology Early Loss of Splenic Tfh Cells in SIV-Infected Rhesus Macaques KAP1 regulates gene networks controlling T-cell development and responsiveness.Regulators of Tfh Cell Differentiation Mechanism of Action of IL-7 and Its Potential Applications and Limitations in Cancer Immunotherapy Signaling by the phosphoinositide 3-kinase family in immune cells The transmembrane adaptor protein SIT inhibits TCR-mediated signaling ECM1 controls T(H)2 cell egress from lymph nodes through re-expression of S1P(1)FAM65B controls the proliferation of transformed and primary T cells.Ex vivo modulation of the Foxo1 phosphorylation state does not lead to dysfunction of T regulatory cells.CD27 stimulation promotes the frequency of IL-7 receptor-expressing memory precursors and prevents IL-12-mediated loss of CD8(+) T cell memory in the absence of CD4(+) T cell help.Mycolactone impairs T cell homing by suppressing microRNA control of L-selectin expression Novel Foxo1-dependent transcriptional programs control T(reg) cell function CXCR4 and a cell-extrinsic mechanism control immature B lymphocyte egress from bone marrow Molecular signature of cell cycle exit induced in human T lymphoblasts by IL-2 withdrawal Interleukin-7 and Immunosenescence.FOXO transcription factors: their clinical significance and regulation.Naïve T cells re-distribute to the lungs of selectin ligand deficient mice.Foxp1 is an essential transcriptional regulator for the generation of quiescent naive T cells during thymocyte development.Basal NF-κB controls IL-7 responsiveness of quiescent naïve T cells Memory CD8+ T cell differentiation Foxo transcription factors control regulatory T cell development and function An Slfn2 mutation causes lymphoid and myeloid immunodeficiency due to loss of immune cell quiescence.The "O" class: crafting clinical care with FoxO transcription factors.KLF2 is a rate-limiting transcription factor that can be targeted to enhance regulatory T-cell production.CD127 expression, exhaustion status and antigen specific proliferation predict sustained virologic response to IFN in HCV/HIV co-infected individuals.The human long noncoding RNA lnc-IL7R regulates the inflammatory response Transcription factors Foxo3a and Foxo1 couple the E3 ligase Cbl-b to the induction of Foxp3 expression in induced regulatory T cells Early events governing memory CD8+ T-cell differentiation.The molecular signature underlying the thymic migration and maturation of TCRαβ+ CD4+ CD8 thymocytes Systemic autoimmunity and lymphoproliferation are associated with excess IL-7 and inhibited by IL-7Rα blockade.Tenuous paths in unexplored territory: From T cell receptor signaling to effector gene expression during thymocyte selection.FOXO3 regulates CD8 T cell memory by T cell-intrinsic mechanisms.TSC1/2 signaling complex is essential for peripheral naïve CD8+ T cell survival and homeostasis in mice.IL-7 signaling must be intermittent, not continuous, during CD8⁺ T cell homeostasis to promote cell survival instead of cell death.

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Foxo1 links homing and survival of naive T cells by regulating L-selectin, CCR7 and interleukin 7 receptor.

http://www.wikidata.org/entity/Q33797113

description

2009 nî lūn-bûn

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2009 թուականի Յունուարին հրատարակուած գիտական յօդուած

@hyw

2009 թվականի հունվարին հրատարակված գիտական հոդված

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2009年の論文

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2009年論文

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2009年論文

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2009年論文

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2009年論文

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2009年論文

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2009年论文

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name

Foxo1 links homing and surviva ...... R7 and interleukin 7 receptor.

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Foxo1 links homing and surviva ...... R7 and interleukin 7 receptor.

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type

label

Foxo1 links homing and surviva ...... R7 and interleukin 7 receptor.

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Foxo1 links homing and surviva ...... R7 and interleukin 7 receptor.

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prefLabel

Foxo1 links homing and surviva ...... R7 and interleukin 7 receptor.

@ast

Foxo1 links homing and surviva ...... R7 and interleukin 7 receptor.

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Nature Immunology

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Foxo1 links homing and surviva ...... CR7 and interleukin 7 receptor

@en

P2093

Anne S Dejean

http://www.w3.org/2001/XMLSchema#string

Daniel R Beisner

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Diego H Castrillon

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Ronald A DePinho

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Stephen M Hedrick

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P2860

Akt promotes cell survival by phosphorylating and inhibiting a Forkhead transcription factor

Control of cell cycle exit and entry by protein kinase B-regulated forkhead transcription factors

FOXO3a-dependent regulation of Puma in response to cytokine/growth factor withdrawal

Expression of the pro-apoptotic Bcl-2 family member Bim is regulated by the forkhead transcription factor FKHR-L1

The forkhead transcription factor FoxO regulates transcription of p27Kip1 and Bim in response to IL-2

Kruppel-like factor 2 regulates thymocyte and T-cell migration

FoxOs are lineage-restricted redundant tumor suppressors and regulate endothelial cell homeostasis

Abnormal angiogenesis in Foxo1 (Fkhr)-deficient mice

Control of cyclin G2 mRNA expression by forkhead transcription factors: novel mechanism for cell cycle control by phosphoinositide 3-kinase and forkhead

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176-184

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10.1038/NI.1689

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2

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19136962

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2856471

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