about
Towards a unifying, systems biology understanding of large-scale cellular death and destruction caused by poorly liganded iron: Parkinson's, Huntington's, Alzheimer's, prions, bactericides, chemical toxicology and others as examplesIn vivo maturation of human frataxinIron-dependent regulation of frataxin expression: implications for treatment of Friedreich ataxiaSplice mutation in the iron-sulfur cluster scaffold protein ISCU causes myopathy with exercise intoleranceMulti-copper oxidases and human iron metabolismMitochondrial iron-sulfur cluster dysfunction in neurodegenerative diseaseStructural characterization of metal binding to a cold-adapted frataxinEvolution based on domain combinations: the case of glutaredoxinsStructural, Mechanistic and Coordination Chemistry of Relevance to the Biosynthesis of Iron-Sulfur and Related Iron CofactorsIron-binding activity in yeast frataxin entails a trade off with stability in the alpha1/beta1 acidic ridge regionHuman frataxin: iron and ferrochelatase binding surface.Mitochondrial iron trafficking and the integration of iron metabolism between the mitochondrion and cytosol.The 1.4 A crystal structure of the ArsD arsenic metallochaperone provides insights into its interaction with the ArsA ATPaseFriedreich ataxia: molecular mechanisms, redox considerations, and therapeutic opportunities.Frataxin and mitochondrial FeS cluster biogenesis.Defects in mitochondrial axonal transport and membrane potential without increased reactive oxygen species production in a Drosophila model of Friedreich ataxiaNormal and Friedreich ataxia cells express different isoforms of frataxin with complementary roles in iron-sulfur cluster assemblyMolecular details of the yeast frataxin-Isu1 interaction during mitochondrial Fe-S cluster assemblyLoss of Frataxin induces iron toxicity, sphingolipid synthesis, and Pdk1/Mef2 activation, leading to neurodegeneration.Small molecules affecting transcription in Friedreich ataxiaIron-sulfur cluster biogenesis and human diseaseFriedreich's ataxia: pathology, pathogenesis, and molecular genetics.Probing the kinetic stabilities of Friedreich's ataxia clinical variants using a solid phase GroEL chaperonin capture platform.Molecular insights into frataxin-mediated iron supply for heme biosynthesis in Bacillus subtilisThe long history of iron in the Universe and in health and disease.Iron loading site on the Fe-S cluster assembly scaffold protein is distinct from the active site.NMR assignments of a stable processing intermediate of human frataxin.Iron chaperones for mitochondrial Fe-S cluster biosynthesis and ferritin iron storageKey players and their role during mitochondrial iron-sulfur cluster biosynthesisIron-sulfur cluster synthesis, iron homeostasis and oxidative stress in Friedreich ataxia.Missense mutations linked to friedreich ataxia have different but synergistic effects on mitochondrial frataxin isoforms.Synthesis, delivery and regulation of eukaryotic heme and Fe-S cluster cofactors.Mitochondrial localization of human frataxin is necessary but processing is not for rescuing frataxin deficiency in Trypanosoma brucei.Architecture of the Yeast Mitochondrial Iron-Sulfur Cluster Assembly Machinery: THE SUB-COMPLEX FORMED BY THE IRON DONOR, Yfh1 PROTEIN, AND THE SCAFFOLD, Isu1 PROTEIN.Assessment of epidermal nerve fibers: a new diagnostic and predictive tool for peripheral neuropathies.Fe-S cluster assembly pathways in bacteria.Drosophila frataxin: an iron chaperone during cellular Fe-S cluster bioassembly.Lateral-flow immunoassay for the frataxin protein in Friedreich's ataxia patients and carriers.Iron uptake and transport in plants: the good, the bad, and the ionome.Metal acquisition and availability in the mitochondria.
P2860
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P2860
description
2006 nî lūn-bûn
@nan
2006 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2006 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
name
The structure and function of frataxin.
@ast
The structure and function of frataxin.
@en
type
label
The structure and function of frataxin.
@ast
The structure and function of frataxin.
@en
prefLabel
The structure and function of frataxin.
@ast
The structure and function of frataxin.
@en
P2093
P2860
P1476
The structure and function of frataxin.
@en
P2093
César Millán-Pacheco
Jeremy D Cook
Kalyan C Kondapalli
Krisztina Z Bencze
Nina Pastor
Stephen McMahon
Timothy L Stemmler
P2860
P304
P356
10.1080/10409230600846058
P577
2006-09-01T00:00:00Z