A strong negative transcriptional regulatory region between the human cytomegalovirus UL127 gene and the major immediate-early enhancer.
about
The human cytomegalovirus major immediate-early distal enhancer region is required for efficient viral replication and immediate-early gene expression.Identification of a boundary domain adjacent to the potent human cytomegalovirus enhancer that represses transcription of the divergent UL127 promoter.The human cytomegalovirus IE86 protein can block cell cycle progression after inducing transition into the S phase of permissive cells.Reactivation of the human cytomegalovirus major immediate-early regulatory region and viral replication in embryonal NTera2 cells: role of trichostatin A, retinoic acid, and deletion of the 21-base-pair repeats and modulator.Two Sp1/Sp3 binding sites in the major immediate-early proximal enhancer of human cytomegalovirus have a significant role in viral replication.Phorbol ester-induced human cytomegalovirus major immediate-early (MIE) enhancer activation through PKC-delta, CREB, and NF-kappaB desilences MIE gene expression in quiescently infected human pluripotent NTera2 cells.Inhibition of cellular DNA synthesis by the human cytomegalovirus IE86 protein is necessary for efficient virus replication.The human cytomegalovirus major immediate-early enhancer determines the efficiency of immediate-early gene transcription and viral replication in permissive cells at low multiplicity of infection.High-efficiency promoter-dependent transduction by adeno-associated virus type 6 vectors in mouse lung.Reversal of human cytomegalovirus major immediate-early enhancer/promoter silencing in quiescently infected cells via the cyclic AMP signaling pathway.The autoregulatory and transactivating functions of the human cytomegalovirus IE86 protein use independent mechanisms for promoter binding.Immediate-Early (IE) gene regulation of cytomegalovirus: IE1- and pp71-mediated viral strategies against cellular defensesDifferentiation-Coupled Induction of Human Cytomegalovirus Replication by Union of the Major Enhancer Retinoic Acid, Cyclic AMP, and NF-κB Response Elements.The CREB site in the proximal enhancer is critical for cooperative interaction with the other transcription factor binding sites to enhance transcription of the major intermediate-early genes in human cytomegalovirus-infected cells.Role of the proximal enhancer of the major immediate-early promoter in human cytomegalovirus replication.Cellular repressor inhibits human cytomegalovirus transcription from the UL127 promoter.Breaking human cytomegalovirus major immediate-early gene silence by vasoactive intestinal peptide stimulation of the protein kinase A-CREB-TORC2 signaling cascade in human pluripotent embryonal NTera2 cells.
P2860
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P2860
A strong negative transcriptional regulatory region between the human cytomegalovirus UL127 gene and the major immediate-early enhancer.
description
1999 nî lūn-bûn
@nan
1999 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
1999 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
1999年の論文
@ja
1999年論文
@yue
1999年論文
@zh-hant
1999年論文
@zh-hk
1999年論文
@zh-mo
1999年論文
@zh-tw
1999年论文
@wuu
name
A strong negative transcriptio ...... ajor immediate-early enhancer.
@ast
A strong negative transcriptio ...... ajor immediate-early enhancer.
@en
type
label
A strong negative transcriptio ...... ajor immediate-early enhancer.
@ast
A strong negative transcriptio ...... ajor immediate-early enhancer.
@en
prefLabel
A strong negative transcriptio ...... ajor immediate-early enhancer.
@ast
A strong negative transcriptio ...... ajor immediate-early enhancer.
@en
P2093
P2860
P1433
P1476
A strong negative transcriptio ...... major immediate-early enhancer
@en
P2093
C A Lundquist
M F Stinski
P2860
P304
P577
1999-11-01T00:00:00Z