High-throughput and ultra-high-throughput screening: solution- and cell-based approaches.
about
Finding the needle in the haystack: why high-throughput screening is good for your health.Metabolite profiling in plant biology: platforms and destinationsTime-Resolved Fluorescence Spectroscopy and Fluorescence Lifetime Imaging Microscopy for Characterization of Dendritic Polymer Nanoparticles and Applications in NanomedicineImproving drug discovery with high-content phenotypic screens by systematic selection of reporter cell linesNew tools and new biology: recent miniaturized systems for molecular and cellular biology.Chemical microarray: a new tool for drug screening and discovery.Use of proximity ligation to screen for inhibitors of interactions between vascular endothelial growth factor A and its receptors.Discovering novel ligands for macromolecules using X-ray crystallographic screening.Selection of bead-displayed, PNA-encoded chemicals.Mirror-image phage display: aiming at the mirror.Chemical genetics: ligand-based discovery of gene function.Assay concordance between SPA and TR-FRET in high-throughput screening.High throughput single molecule detection for monitoring biochemical reactionsSingle cell kinase signaling assay using pinched flow coupled droplet microfluidics.Polymer-based dense fluidic networks for high throughput screening with ultrasensitive fluorescence detection.Novel concept microarray enabling PCR and multistep reactions through pipette-free aperture-to-aperture parallel transferEstimation of affinities of ligands in mixtures via magnetic recovery of target-ligand complexes and chromatographic analyses: chemometrics and an experimental model.PubChem3D: Biologically relevant 3-D similaritySolution-phase synthesis of a highly substituted furan library.Induced cancer stem-like cells as a model for biological screening and discovery of agents targeting phenotypic traits of cancer stem cell.Target identification and mechanism of action in chemical biology and drug discovery.Real-time cytotoxicity assays in human whole blood.Rapid, single-molecule assays in nano/micro-fluidic chips with arrays of closely spaced parallel channels fabricated by femtosecond laser machining.Establishment of a reborn MMV-microarray technology: realization of microbiome analysis and other hitherto inaccessible technologiesThe use of 3-D cultures for high-throughput screening: the multicellular spheroid model.Low potency toxins reveal dense interaction networks in metabolism.Non-positional cell microarray prepared by shape-coded polymeric microboards: A new microarray format for multiplex and high throughput cell-based assays.Assaying Bcr-Abl kinase activity and inhibition in whole cell extracts by phosphorylation of substrates immobilized on agarose beads.Determining the mode of action of anti-mycobacterial C17 diyne natural products using expression profiling: evidence for fatty acid biosynthesis inhibition.HTSvis: a web app for exploratory data analysis and visualization of arrayed high-throughput screens.Lab-on-a-chip: microfluidics in drug discovery.Patient-derived stem cells: pathways to drug discovery for brain diseases.Biological screening of natural products and drug innovation in China.The potential of bioartificial tissues in oncology research and treatment.Image-based evaluation of the molecular events underlying HC11 mammary epithelial cell differentiation.Liquid biopsy and therapeutic response: Circulating tumor cell cultures for evaluation of anticancer treatment.Cell migration and invasion assays as tools for drug discovery.Non-clinical studies required for new drug development - Part I: early in silico and in vitro studies, new target discovery and validation, proof of principles and robustness of animal studies.Liquid gradient in two-dimensional matrix for high throughput screening.Act on the Registration and Evaluation of Chemicals (K-REACH) and replacement, reduction or refinement best practices.
P2860
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P2860
High-throughput and ultra-high-throughput screening: solution- and cell-based approaches.
description
2000 nî lūn-bûn
@nan
2000 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2000 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2000年の論文
@ja
2000年論文
@yue
2000年論文
@zh-hant
2000年論文
@zh-hk
2000年論文
@zh-mo
2000年論文
@zh-tw
2000年论文
@wuu
name
High-throughput and ultra-high-throughput screening: solution- and cell-based approaches.
@ast
High-throughput and ultra-high-throughput screening: solution- and cell-based approaches.
@en
type
label
High-throughput and ultra-high-throughput screening: solution- and cell-based approaches.
@ast
High-throughput and ultra-high-throughput screening: solution- and cell-based approaches.
@en
prefLabel
High-throughput and ultra-high-throughput screening: solution- and cell-based approaches.
@ast
High-throughput and ultra-high-throughput screening: solution- and cell-based approaches.
@en
P1476
High-throughput and ultra-high-throughput screening: solution- and cell-based approaches.
@en
P2093
Sundberg SA
P356
10.1016/S0958-1669(99)00051-8
P577
2000-02-01T00:00:00Z