Characterization of novel cathepsin K mutations in the pro and mature polypeptide regions causing pycnodysostosis.
about
Inhibitory mechanism of a cross-class serpin, the squamous cell carcinoma antigen 1Structure-Activity Analysis of Cathepsin K/Chondroitin 4-Sulfate InteractionsBiochemical markers of ongoing joint damage in rheumatoid arthritis--current and future applications, limitations and opportunities.Pharmacological chaperones rescue cell-surface expression and function of misfolded V2 vasopressin receptor mutantsThe Plasmodium falciparum cysteine protease falcipain-2 captures its substrate, hemoglobin, via a unique motif.Collagenase activity of cathepsin K depends on complex formation with chondroitin sulfate.Molecular and clinical analysis in a series of patients with Pyknodysostosis reveals some uncommon phenotypic findings.Insights from bacterial subtilases into the mechanisms of intramolecular chaperone-mediated activation of furinClinical and animal research findings in pycnodysostosis and gene mutations of cathepsin K from 1996 to 2011Cathepsin k is a critical protease in synovial fibroblast-mediated collagen degradation.The role of basic amino acid surface clusters on the collagenase activity of cathepsin KNovel Compound Heterozygous Mutations in the Cathepsin K Gene in Japanese Female Siblings with PyknodysostosisTranscriptome Reveals Cathepsin K in Periodontal Ligament Differentiation.The consequences of lysosomotropism on the design of selective cathepsin K inhibitors.Molecular analysis of the CTSK gene in a cohort of 33 Brazilian families with pycnodysostosis from a cluster in a Brazilian Northeast region.Bone marrow-derived cathepsin K cleaves SPARC in bone metastasis.A mutation in CTSK gene in an autosomal recessive pycnodysostosis family of Pakistani originBiochemical markers and the FDA Critical Path: how biomarkers may contribute to the understanding of pathophysiology and provide unique and necessary tools for drug development.The role of cathepsin K in oral and maxillofacial disorders.Cathepsin K osteoporosis trials, pycnodysostosis and mouse deficiency models: Commonalities and differences.Inherited diseases caused by mutations in cathepsin protease genes.Pycnodysostosis with Multi-Segmental Spinal Canal Stenosis due to Ossification of the Yellow Ligament.Novel mutation and white matter involvement in an Indian child with pycnodysostosis.Dental Abnormalities Caused by Novel Compound Heterozygous CTSK Mutations.The crystal structure of a Cys25 -> Ala mutant of human procathepsin S elucidates enzyme-prosequence interactions.Imbalance between cysteine proteases and inhibitors in a baboon model of bronchopulmonary dysplasia.Chondroitin sulfate promotes activation of cathepsin K.Structural requirements for the collagenase and elastase activity of cathepsin K and its selective inhibition by an exosite inhibitor.Expression of cysteine proteinases cathepsins B and K and of cysteine proteinase inhibitor cystatin C in giant cell tumor of tendon sheath.Role of the prosegment of Fasciola hepatica cathepsin L1 in folding of the catalytic domain.Challenges in the orthodontic treatment of a patient with pycnodysostosis.Pycnodysostosis: Novel Variants in CTSK and Occurrence of Giant Cell Tumor.An Ectosteric Inhibitor of Cathepsin K Inhibits Bone Resorption in Ovariectomized Mice.Novel CTSK mutation resulting in an entire exon 2 skipping in a Thai girl with pycnodysostosis.
P2860
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P2860
Characterization of novel cathepsin K mutations in the pro and mature polypeptide regions causing pycnodysostosis.
description
1999 nî lūn-bûn
@nan
1999 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
1999 թվականի մարտին հրատարակված գիտական հոդված
@hy
1999年の論文
@ja
1999年論文
@yue
1999年論文
@zh-hant
1999年論文
@zh-hk
1999年論文
@zh-mo
1999年論文
@zh-tw
1999年论文
@wuu
name
Characterization of novel cath ...... gions causing pycnodysostosis.
@ast
Characterization of novel cath ...... gions causing pycnodysostosis.
@en
type
label
Characterization of novel cath ...... gions causing pycnodysostosis.
@ast
Characterization of novel cath ...... gions causing pycnodysostosis.
@en
prefLabel
Characterization of novel cath ...... gions causing pycnodysostosis.
@ast
Characterization of novel cath ...... gions causing pycnodysostosis.
@en
P2093
P2860
P356
P1476
Characterization of novel cath ...... egions causing pycnodysostosis
@en
P2093
C S Miranda
D L Rimoin
R J Desnick
P2860
P304
P356
10.1172/JCI653
P407
P577
1999-03-01T00:00:00Z