Short telomeres compromise β-cell signaling and survival. - Test2 - elhamkhani - TriplyDB

Short telomeres compromise β-cell signaling and survival.

Short telomeres compromise β-cell signaling and survival.

http://www.wikidata.org/entity/Q33851700

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The telomere syndromes Cellular senescence in aging and age-related disease: from mechanisms to therapy The short and long telomere syndromes: paired paradigms for molecular medicine Telomerase and idiopathic pulmonary fibrosis Axis of ageing: telomeres, p53 and mitochondria Changes in stress, eating, and metabolic factors are related to changes in telomerase activity in a randomized mindfulness intervention pilot study Islet biology, the CDKN2A/B locus and type 2 diabetes risk.Age-related impairment of pancreatic Beta-cell function: pathophysiological and cellular mechanisms.Leucocyte telomere length and risk of type 2 diabetes mellitus: new prospective cohort study and literature-based meta-analysis Telomere length is a determinant of emphysema susceptibility.Telomere dysfunction causes alveolar stem cell failure Tired telomeres: Poor global sleep quality, perceived stress, and telomere length in immune cell subsets in obese men and women Hepatopulmonary syndrome is a frequent cause of dyspnea in the short telomere disorders.Leukocyte Telomere Length in the Neonatal Offspring of Mothers with Gestational and Pre-Gestational Diabetes The interaction between the yeast telomerase RNA and the Est1 protein requires three structural elements.Shortened leukocyte telomere length in type 2 diabetes mellitus: genetic polymorphisms in mitochondrial uncoupling proteins and telomeric pathways.Telomeres and age-related disease: how telomere biology informs clinical paradigms Genetic modifiers of cystic fibrosis-related diabetes Interactions between UCP2 SNPs and telomere length exist in the absence of diabetes or pre-diabetes.Multiple genetic pathways regulate replicative senescence in telomerase-deficient yeast.The role of telomere shortening in somatic stem cells and tissue aging: lessons from telomerase model systems.Telomeres and human health.Transcriptional outcome of telomere signalling.Telomere attrition and diabetes mellitus.Are microRNAs true sensors of ageing and cellular senescence?The Telomeric Complex and Metabolic Disease Accelerated aging as evidenced by increased telomere shortening and mitochondrial DNA depletion in patients with type 2 diabetes.Longer Telomere Length and its Association with Lower Levels of C-Peptide.Telomere shortening is associated with reduced duodenal HCOFormula secretory but normal gastric acid secretory capacity in aging mice.Upstream signalling of mTORC1 and its hyperactivation in type 2 diabetes (T2D).β Cell Aging Markers Have Heterogeneous Distribution and Are Induced by Insulin Resistance.Genome-wide association study identified new susceptibility loci for polycystic ovary syndrome.Short Leukocyte Telomere Length Predicts Albuminuria Progression in Individuals With Type 2 Diabetes.

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P2860

Short telomeres compromise β-cell signaling and survival.

http://www.wikidata.org/entity/Q33851700

description

2011 nî lūn-bûn

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2011 թուականի Մարտին հրատարակուած գիտական յօդուած

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2011 թվականի մարտին հրատարակված գիտական հոդված

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2011年の論文

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2011年論文

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2011年論文

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2011年論文

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2011年論文

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2011年論文

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2011年论文

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Short telomeres compromise β-cell signaling and survival.

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Short telomeres compromise β-cell signaling and survival.

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Short telomeres compromise β-cell signaling and survival.

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Short telomeres compromise β-cell signaling and survival.

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Short telomeres compromise β-cell signaling and survival.

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Short telomeres compromise β-cell signaling and survival.

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Short telomeres compromise β-cell signaling and survival.

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Erin M Parry

http://www.w3.org/2001/XMLSchema#string

Frant Kembou

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Luo-Sheng Li

http://www.w3.org/2001/XMLSchema#string

Mehboob A Hussain

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Naudia Lauder

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Nini Guo

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P2860

A novel gene activated in regenerating islets

Haploinsufficiency of telomerase reverse transcriptase leads to anticipation in autosomal dominant dyskeratosis congenita

Genetic heterogeneity in autosomal recessive dyskeratosis congenita with one subtype due to mutations in the telomerase-associated protein NOP10

Telomerase deficiency impairs glucose metabolism and insulin secretion

Summaries of Affymetrix GeneChip probe level data

The role of voltage-gated calcium channels in pancreatic beta-cell physiology and pathophysiology.

The RNA component of telomerase is mutated in autosomal dominant dyskeratosis congenita

p16INK4a induces an age-dependent decline in islet regenerative potential

Targeted disruption of the Chop gene delays endoplasmic reticulum stress-mediated diabetes

Exendin-4 stimulates both beta-cell replication and neogenesis, resulting in increased beta-cell mass and improved glucose tolerance in diabetic rats

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Per-Olof Berggren

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50597277

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