Structural determinants for recognition and translocation by the anandamide transporter. - Test2 - elhamkhani - TriplyDB

Structural determinants for recognition and translocation by the anandamide transporter.

Structural determinants for recognition and translocation by the anandamide transporter.

http://www.wikidata.org/entity/Q33861497

about

Brain monoglyceride lipase participating in endocannabinoid inactivation The endocannabinoid system as a target for the treatment of cannabis dependence Emerging roles for endocannabinoids in long-term synaptic plasticity Evidence against the presence of an anandamide transporter Substrate selectivity of bacterial monoacylglycerol lipase based on crystal structure Human platelets bind and degrade 2-arachidonoylglycerol, which activates these cells through a cannabinoid receptor Conversion of acetaminophen to the bioactive N-acylphenolamine AM404 via fatty acid amide hydrolase-dependent arachidonic acid conjugation in the nervous system Identification of a high-affinity binding site involved in the transport of endocannabinoids.Characterization of palmitoylethanolamide transport in mouse Neuro-2a neuroblastoma and rat RBL-2H3 basophilic leukaemia cells: comparison with anandamide Cannabinoid-receptor-independent cell signalling by N-acylethanolamines Cannabinoids and the gastrointestinal tract Keys to Lipid Selection in Fatty Acid Amide Hydrolase Catalysis: Structural Flexibility, Gating Residues and Multiple Binding Pockets The evolution and comparative neurobiology of endocannabinoid signalling Cannabinoid receptor ligands: clinical and neuropharmacological considerations, relevant to future drug discovery and development.Gas chromatography-mass spectrometry analysis of endogenous cannabinoids in healthy and tumoral human brain and human cells in culture.The neurobiology of individual differences in complex behavioral traits.Characterization of an AM404 analogue, N-(3-hydroxyphenyl)arachidonoylamide, as a substrate and inactivator of prostaglandin endoperoxide synthase.Endocannabinoids in the dentate gyrus.2012 Division of medicinal chemistry award address. Trekking the cannabinoid road: a personal perspective The uptake by cells of 2-arachidonoylglycerol, an endogenous agonist of cannabinoid receptors.Enhancement of endocannabinoid signaling by fatty acid amide hydrolase inhibition: a neuroprotective therapeutic modality Increased angiotensin II contraction of the uterine artery at early gestation in a transgenic model of hypertensive pregnancy is reduced by inhibition of endocannabinoid hydrolysis.Binding, degradation and apoptotic activity of stearoylethanolamide in rat C6 glioma cells.Anandamide transport is independent of fatty-acid amide hydrolase activity and is blocked by the hydrolysis-resistant inhibitor AM1172.New potent and selective inhibitors of anandamide reuptake with antispastic activity in a mouse model of multiple sclerosis Cellular accumulation of anandamide: consensus and controversy.Divergent effects of genetic variation in endocannabinoid signaling on human threat- and reward-related brain function 2-Arachidonoylglycerol (2-AG) membrane transport: history and outlook A catalytically silent FAAH-1 variant drives anandamide transport in neurons.Fatty acid-binding proteins transport N-acylethanolamines to nuclear receptors and are targets of endocannabinoid transport inhibitors.A role for the anandamide membrane transporter in TRPV1-mediated neurosecretion from trigeminal sensory neurons.Critical enzymes involved in endocannabinoid metabolism The endocannabinoid signaling system: a potential target for next-generation therapeutics for alcoholism.Evidence for bidirectional endocannabinoid transport across cell membranes Retrograde endocannabinoid signaling at striatal synapses requires a regulated postsynaptic release step.Targeting the endocannabinoid system in treating brain disorders.Studies of anandamide accumulation inhibitors in cerebellar granule neurons: comparison to inhibition of fatty acid amide hydrolase The cannabinoid system and its pharmacological manipulation--a review, with emphasis upon the uptake and hydrolysis of anandamide.Role of the cannabinoid system in pain control and therapeutic implications for the management of acute and chronic pain episodes.The endocannabinoid system in brain reward processes

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P2860

Structural determinants for recognition and translocation by the anandamide transporter.

http://www.wikidata.org/entity/Q33861497

description

1999 nî lūn-bûn

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1999 թուականի Մայիսին հրատարակուած գիտական յօդուած

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1999 թվականի մայիսին հրատարակված գիտական հոդված

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1999年の論文

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1999年論文

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1999年論文

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1999年論文

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1999年論文

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1999年論文

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1999年论文

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Structural determinants for recognition and translocation by the anandamide transporter.

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Structural determinants for recognition and translocation by the anandamide transporter.

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type

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Structural determinants for recognition and translocation by the anandamide transporter.

@ast

Structural determinants for recognition and translocation by the anandamide transporter.

@en

prefLabel

Structural determinants for recognition and translocation by the anandamide transporter.

@ast

Structural determinants for recognition and translocation by the anandamide transporter.

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Proceedings of the National Academy of Sciences of the United States of America

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Structural determinants for recognition and translocation by the anandamide transporter.

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A Goutopoulos

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D Piomelli

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M Beltramo

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S Glasnapp

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P2860

A family of fatty acid transporters conserved from mycobacterium to man

(R)-methanandamide: a chiral novel anandamide possessing higher potency and metabolic stability

A second endogenous cannabinoid that modulates long-term potentiation

2-Arachidonoylglycerol: a possible endogenous cannabinoid receptor ligand in brain

Identification of an endogenous 2-monoglyceride, present in canine gut, that binds to cannabinoid receptors

Molecular characterization of an enzyme that degrades neuromodulatory fatty-acid amides

Isolation and structure of a brain constituent that binds to the cannabinoid receptor

Formation and inactivation of endogenous cannabinoid anandamide in central neurons

Expression cloning and characterization of a novel adipocyte long chain fatty acid transport protein.

Functional role of high-affinity anandamide transport, as revealed by selective inhibition.

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Alexandros Makriyannis

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12979623

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