Genetic variation at a single locus and age of onset for Alzheimer's disease. - Test2 - elhamkhani - TriplyDB

Genetic variation at a single locus and age of onset for Alzheimer's disease.

Genetic variation at a single locus and age of onset for Alzheimer's disease.

http://www.wikidata.org/entity/Q33870512

about

Characterization of the poly-T variant in the TOMM40 gene in diverse populations A comprehensive genetic association study of Alzheimer disease in African Americans.Meta-analysis of the rs2075650 polymorphism and risk of Alzheimer disease.ApoE4 induces Aβ42, tau, and neuronal pathology in the hippocampus of young targeted replacement apoE4 mice.APOE ε4-TOMM40 '523 haplotypes and the risk of Alzheimer's disease in older Caucasian and African Americans The cis-regulatory effect of an Alzheimer's disease-associated poly-T locus on expression of TOMM40 and apolipoprotein E genes.Are APOE ɛ genotype and TOMM40 poly-T repeat length associations with cognitive ageing mediated by brain white matter tract integrity?Alzheimer's disease susceptibility genes APOE and TOMM40, and hippocampal volumes in the Lothian birth cohort 1936.The effect of TOMM40 poly-T length on gray matter volume and cognition in middle-aged persons with APOE ε3/ε3 genotype.The Broad Impact of TOM40 on Neurodegenerative Diseases in Aging Cerebrospinal fluid cortisol concentrations in healthy elderly are affected by both APOE and TOMM40 variants.Genomics of Dementia: APOE- and CYP2D6-Related Pharmacogenetics.Alzheimer's disease: a clinical practice-oriented review.Levels of cerebrospinal fluid neurofilament light protein in healthy elderly vary as a function of TOMM40 variants A homopolymer polymorphism in the TOMM40 gene contributes to cognitive performance in aging Longitudinal modeling of cognitive aging and the TOMM40 effect.New genes and new insights from old genes: update on Alzheimer disease.Alzheimer's disease susceptibility genes APOE and TOMM40, and brain white matter integrity in the Lothian Birth Cohort 1936.Modeling the dementia epidemic.TOMM40'523 variant and cognitive decline in older persons with APOE ε3/3 genotype.The Biological Foundation of the Genetic Association of TOMM40 with Late-onset Alzheimer's disease.Hippocampal thinning linked to longer TOMM40 poly-T variant lengths in the absence of the APOE ε4 variant.Polymorphisms within ASTN2 gene are associated with age at onset of Alzheimer's disease.APOE/TOMM40 genetic loci, white matter hyperintensities, and cerebral microbleeds.Alzheimer's disease: diagnostics, prognostics and the road to prevention.TOMM40 poly-T variants and cerebrospinal fluid amyloid beta levels in the elderly.NRG3 gene is associated with the risk and age at onset of Alzheimer disease.APOE E4 status predicts age-related cognitive decline in the ninth decade: longitudinal follow-up of the Lothian Birth Cohort 1921.The TOMM40 poly-T rs10524523 variant is associated with cognitive performance among non-demented elderly with type 2 diabetes.TOMM40 and APOE Gene Expression and Cognitive Decline in Japanese Alzheimer's Disease Subjects.Family history and TOMM40 '523 interactive associations with memory in middle-aged and Alzheimer's disease cohorts.Warning SINEs: Alu elements, evolution of the human brain, and the spectrum of neurological disease.Associations between TOMM40 Poly-T Repeat Variants and Dementia in Cases with Parkinsonism.Neuropathologic features of TOMM40 '523 variant on late-life cognitive decline.Future Trends in the Pharmacogenomics of Brain Disorders and Dementia: Influence of APOE and CYP2D6 Variants.

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Genetic variation at a single locus and age of onset for Alzheimer's disease.

http://www.wikidata.org/entity/Q33870512

description

2010 nî lūn-bûn

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2010 թուականի Մարտին հրատարակուած գիտական յօդուած

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2010 թվականի մարտին հրատարակված գիտական հոդված

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2010年の論文

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2010年論文

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2010年論文

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2010年論文

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2010年論文

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2010年論文

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2010年论文

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Genetic variation at a single locus and age of onset for Alzheimer's disease.

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Genetic variation at a single locus and age of onset for Alzheimer's disease.

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Genetic variation at a single locus and age of onset for Alzheimer's disease.

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Genetic variation at a single locus and age of onset for Alzheimer's disease.

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Genetic variation at a single locus and age of onset for Alzheimer's disease.

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Genetic variation at a single locus and age of onset for Alzheimer's disease.

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P356

J.JALZ.2010.01.011

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Alzheimer's and Dementia

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Genetic variation at a single locus and age of onset for Alzheimer's disease

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Allen D Roses

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Ann M Saunders

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Donna G Crenshaw

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P2860

Apolipoprotein E: high-avidity binding to beta-amyloid and increased frequency of type 4 allele in late-onset familial Alzheimer disease

Genome-wide association studies, field synopses, and the development of the knowledge base on genetic variation and human diseases

Genetic variation in PCDH11X is associated with susceptibility to late-onset Alzheimer's disease

Genome-wide association study identifies variants at CLU and PICALM associated with Alzheimer's disease

Robust sequence selection method used to develop the FluChip diagnostic microarray for influenza virus

Constant relative rate of protein evolution and detection of functional diversification among bacterial, archaeal and eukaryotic proteins

Gene dose of apolipoprotein E type 4 allele and the risk of Alzheimer's disease in late onset families

Giant panda genomic data provide insight into the birth-and-death process of mammalian major histocompatibility complex class II genes

Genome-wide association study identifies variants at CLU and CR1 associated with Alzheimer's disease

Association of apolipoprotein E allele epsilon 4 with late-onset familial and sporadic Alzheimer's disease

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125-131

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10.1016/J.JALZ.2010.01.011

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Michael W. Lutz

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Alzheimer's disease

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2874876

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