Binding of aminoglycoside antibiotics to helix 69 of 23S rRNA
about
4′-O-substitutions determine selectivity of aminoglycoside antibioticsCharge reduction and thermodynamic stabilization of substrate RNAs inhibit RNA editingInterplay of the bacterial ribosomal A-site, S12 protein mutations and paromomycin binding: a molecular dynamics study.A novel role of cytosolic protein synthesis inhibition in aminoglycoside ototoxicity.New trends in aminoglycosides use.Functional recognition of the modified human tRNALys3(UUU) anticodon domain by HIV's nucleocapsid protein and a peptide mimic.Selection of heptapeptides that bind helix 69 of bacterial 23S ribosomal RNACharacterization of ribosomal binding and antibacterial activities using two orthogonal high-throughput screensIndigenous and acquired modifications in the aminoglycoside binding sites of Pseudomonas aeruginosa rRNAs.Misannotations of rRNA can now generate 90% false positive protein matches in metatranscriptomic studies.Nucleotide modifications and tRNA anticodon-mRNA codon interactions on the ribosomeEvidence That Antibiotics Bind to Human Mitochondrial Ribosomal RNA Has Implications for Aminoglycoside Toxicity.Chemically related 4,5-linked aminoglycoside antibiotics drive subunit rotation in opposite directionsSmall Molecule-Based Pattern Recognition To Classify RNA Structure.Polymyxins and analogues bind to ribosomal RNA and interfere with eukaryotic translation in vitro.Therapeutics based on stop codon readthrough.Analysis of ribosomal inter-subunit sites as targets for complementary oligonucleotides.Detection and Quantification of Ribosome Inhibition by Aminoglycoside Antibiotics in Living Bacteria Using an Orthogonal Ribosome-Controlled Fluorescent ReporterThe development of peptide ligands that target helix 69 rRNA of bacterial ribosomes.Comparison of solution conformations and stabilities of modified helix 69 rRNA analogs from bacteria and humanImpairment of ribosomal subunit synthesis in aminoglycoside-treated ribonuclease mutants of Escherichia coli.Role of pseudouridine in structural rearrangements of helix 69 during bacterial ribosome assembly.Ligand- and pH-induced conformational changes of RNA domain helix 69 revealed by 2-aminopurine fluorescence.Protein Synthesis Inhibition and Activation of the c-Jun N-Terminal Kinase Are Potential Contributors to Cisplatin Ototoxicity.Mutations in Gene fusA1 as a Novel Mechanism of Aminoglycoside Resistance in Clinical Strains of Pseudomonas aeruginosa.Toward inclusive therapy with CFTR modulators: Progress and challenges.Mitochondrial ribosome and Ménière's disease: a pilot study.Chemical Interrogation of Drug/RNA Complexes: From Chemical Reactivity to Drug Design
P2860
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P2860
Binding of aminoglycoside antibiotics to helix 69 of 23S rRNA
description
2010 nî lūn-bûn
@nan
2010 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Binding of aminoglycoside antibiotics to helix 69 of 23S rRNA
@ast
Binding of aminoglycoside antibiotics to helix 69 of 23S rRNA
@en
type
label
Binding of aminoglycoside antibiotics to helix 69 of 23S rRNA
@ast
Binding of aminoglycoside antibiotics to helix 69 of 23S rRNA
@en
prefLabel
Binding of aminoglycoside antibiotics to helix 69 of 23S rRNA
@ast
Binding of aminoglycoside antibiotics to helix 69 of 23S rRNA
@en
P2093
P2860
P356
P1476
Binding of aminoglycoside antibiotics to helix 69 of 23S rRNA
@en
P2093
Ann E Scheunemann
Franck A P Vendeix
Paul F Agris
William D Graham
P2860
P304
P356
10.1093/NAR/GKP1253
P407
P577
2010-01-27T00:00:00Z