Mechanical strain opens connexin 43 hemichannels in osteocytes: a novel mechanism for the release of prostaglandin - Test2 - elhamkhani - TriplyDB

Mechanical strain opens connexin 43 hemichannels in osteocytes: a novel mechanism for the release of prostaglandin

Mechanical strain opens connexin 43 hemichannels in osteocytes: a novel mechanism for the release of prostaglandin

http://www.wikidata.org/entity/Q33876996

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Connexins: a myriad of functions extending beyond assembly of gap junction channels Sost down-regulation by mechanical strain in human osteoblastic cells involves PGE2 signaling via EP4 The amazing osteocyte Purinergic Signaling in Gut Inflammation: The Role of Connexins and Pannexins Role of Astroglial Hemichannels and Pannexons in Memory and Neurodegenerative Diseases Intracellular Cleavage of the Cx43 C-Terminal Domain by Matrix-Metalloproteases: A Novel Contributor to Inflammation?Diseases associated with leaky hemichannels Biology of Bone Tissue: Structure, Function, and Factors That Influence Bone Cells Gap junctional regulation of signal transduction in bone cells Roles of gap junctions, connexins, and pannexins in epilepsy The role of connexins in ear and skin physiology - functional insights from disease-associated mutations Functional analysis and regulation of purified connexin hemichannels In vitro and in vivo approaches to study osteocyte biology Cxs and Panx- hemichannels in peripheral and central chemosensing in mammals Functions of the osteocyte network in the regulation of bone mass Osteocytes: master orchestrators of bone Connexin 43 hemichannels and intracellular signaling in bone cells Connexins and Pannexins: New Insights into Microglial Functions and Dysfunctions Mechanotransduction as an Adaptation to Gravity.14-3-3θ facilitates plasma membrane delivery and function of mechanosensitive connexin 43 hemichannels Osteoblast connexin43 modulates skeletal architecture by regulating both arms of bone remodeling Pannexin channel and connexin hemichannel expression in vascular function and inflammation Direct regulation of osteocytic connexin 43 hemichannels through AKT kinase activated by mechanical stimulation Mechanical stress-activated integrin α5β1 induces opening of connexin 43 hemichannels.Diffusion modeling of ATP signaling suggests a partially regenerative mechanism underlies astrocyte intercellular calcium waves.Concerted stimuli regulating osteo-chondral differentiation from stem cells: phenotype acquisition regulated by microRNAs.Fluid and Solute Transport in Bone: Flow-Induced Mechanotransduction Biomechanics of cardiac electromechanical coupling and mechanoelectric feedback.Nuclear factor of activated T cells mediates fluid shear stress- and tensile strain-induced Cox2 in human and murine bone cells.Integrative transcriptomic and proteomic analysis of osteocytic cells exposed to fluid flow reveals novel mechano-sensitive signaling pathways.Opening of pannexin- and connexin-based channels increases the excitability of nodose ganglion sensory neurons.Dendritic processes of osteocytes are mechanotransducers that induce the opening of hemichannels.Oscillating fluid flow activation of gap junction hemichannels induces ATP release from MLO-Y4 osteocytes.A Trabecular Bone Explant Model of Osteocyte-Osteoblast Co-Culture for Bone Mechanobiology.Activation of β-catenin signaling in MLO-Y4 osteocytic cells versus 2T3 osteoblastic cells by fluid flow shear stress and PGE2: Implications for the study of mechanosensation in bone Characterization of hTERT-immortalized osteoblast cell lines generated from wild-type and connexin43-null mouse calvaria.Aquaporin 0 enhances gap junction coupling via its cell adhesion function and interaction with connexin 50.S-nitrosylation and permeation through connexin 43 hemichannels in astrocytes: induction by oxidant stress and reversal by reducing agents.Connexin43 hemichannel-mediated regulation of connexin43.A new method to investigate how mechanical loading of osteocytes controls osteoblasts

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P2860

Mechanical strain opens connexin 43 hemichannels in osteocytes: a novel mechanism for the release of prostaglandin

http://www.wikidata.org/entity/Q33876996

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2005 nî lūn-bûn

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2005 թուականի Ապրիլին հրատարակուած գիտական յօդուած

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2005 թվականի ապրիլին հրատարակված գիտական հոդված

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2005年の論文

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Mechanical strain opens connex ...... r the release of prostaglandin

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Mechanical strain opens connex ...... r the release of prostaglandin

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MBC.E04-10-0912

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Molecular Biology of the Cell

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Mechanical strain opens connex ...... r the release of prostaglandin

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Arlene J Siller-Jackson

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Eugene Sprague

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Jean X Jiang

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Lynda F Bonewald

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Priscilla P Cherian

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Sumin Gu

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Xin Wang

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P2860

Molecular physiology of P2X receptors

Transduction of cell survival signals by connexin-43 hemichannels.

Human prostaglandin transporter gene (hPGT) is regulated by fluid mechanical stimuli in cultured endothelial cells and expressed in vascular endothelium in vivo.

Beyond the gap: functions of unpaired connexon channels.

Prostanoid receptors: subtypes and signaling.

Molecular basis of calcium regulation in connexin-32 hemichannels

Prostaglandin transport.

Molecular cloning and spatio-temporal expression of the prostaglandin transporter: a basis for the action of prostaglandins in the bovine reproductive system

Analyzing phorbol ester effects on gap junctional communication: a dramatic inhibition of assembly

Physiological role of gap-junctional hemichannels. Extracellular calcium-dependent isosmotic volume regulation.

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3100-3106

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10.1091/MBC.E04-10-0912

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7

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15843434

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1165395

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