Upregulation of steroidogenic acute regulatory protein by hypoxia stimulates aldosterone synthesis in pulmonary artery endothelial cells to promote pulmonary vascular fibrosis.
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Emerging Concepts in the Molecular Basis of Pulmonary Arterial Hypertension: Part II: Neurohormonal Signaling Contributes to the Pulmonary Vascular and Right Ventricular Pathophenotype of Pulmonary Arterial HypertensionInvolvement Of Vascular Aldosterone Synthase In Phosphate-Induced Osteogenic Transformation Of Vascular Smooth Muscle Cells.Systems medicine: evolution of systems biology from bench to bedsideOxymatrine inhibits aldosterone-induced rat cardiac fibroblast proliferation and differentiation by attenuating smad-2,-3 and-4 expression: an in vitro studyElevated pulmonary arterial and systemic plasma aldosterone levels associate with impaired cardiac reserve capacity during exercise in left ventricular systolic heart failure patients: A pilot study.Up-regulation of the mammalian target of rapamycin complex 1 subunit Raptor by aldosterone induces abnormal pulmonary artery smooth muscle cell survival patterns to promote pulmonary arterial hypertensionPulmonary vascular and ventricular dysfunction in the susceptible patient (2015 Grover Conference series).Transcription factors regulate GPR91-mediated expression of VEGF in hypoxia-induced retinopathy.30 YEARS OF THE MINERALOCORTICOID RECEPTOR: The role of the mineralocorticoid receptor in the vasculature.Absence of the inflammasome adaptor ASC reduces hypoxia-induced pulmonary hypertension in mice.Update on novel targets and potential treatment avenues in pulmonary hypertension.A Time- and Compartment-Specific Activation of Lung Macrophages in Hypoxic Pulmonary Hypertension.Global transcriptomic analysis suggests carbon dioxide as an environmental stressor in spaceflight: A systems biology GeneLab case study.Eplerenone attenuates pathological pulmonary vascular rather than right ventricular remodeling in pulmonary arterial hypertension.
P2860
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P2860
Upregulation of steroidogenic acute regulatory protein by hypoxia stimulates aldosterone synthesis in pulmonary artery endothelial cells to promote pulmonary vascular fibrosis.
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name
Upregulation of steroidogenic ...... e pulmonary vascular fibrosis.
@ast
Upregulation of steroidogenic ...... e pulmonary vascular fibrosis.
@en
type
label
Upregulation of steroidogenic ...... e pulmonary vascular fibrosis.
@ast
Upregulation of steroidogenic ...... e pulmonary vascular fibrosis.
@en
prefLabel
Upregulation of steroidogenic ...... e pulmonary vascular fibrosis.
@ast
Upregulation of steroidogenic ...... e pulmonary vascular fibrosis.
@en
P2093
P2860
P1433
P1476
Upregulation of steroidogenic ...... e pulmonary vascular fibrosis.
@en
P2093
Bradley A Maron
Elena Arons
Jane A Leopold
Sara O Vargas
Stephen Y Chan
William M Oldham
Ying-Yi Zhang
P2860
P304
P356
10.1161/CIRCULATIONAHA.113.007690
P407
P577
2014-04-28T00:00:00Z