Evaluating the immunogenicity of a disulfide-stabilized, cleaved, trimeric form of the envelope glycoprotein complex of human immunodeficiency virus type 1
about
Aiming to induce broadly reactive neutralizing antibody responses with HIV-1 vaccine candidatesTwo HIV-1 variants resistant to small molecule CCR5 inhibitors differ in how they use CCR5 for entryA directed molecular evolution approach to improved immunogenicity of the HIV-1 envelope glycoproteinRecent advances on the use of structural biology for the design of novel envelope immunogens of HIV-1Comparison of immunogenicity between codon optimized HIV-1 Thailand subtype B gp140 and gp145 vaccines.Progress on the induction of neutralizing antibodies against HIV type 1 (HIV-1).Stabilized HIV-1 envelope glycoprotein trimers for vaccine use.Llama antibody fragments with cross-subtype human immunodeficiency virus type 1 (HIV-1)-neutralizing properties and high affinity for HIV-1 gp120Preparation of recombinant viral glycoproteins for novel and therapeutic antibody discovery.Effect of trimerization motifs on quaternary structure, antigenicity, and immunogenicity of a noncleavable HIV-1 gp140 envelope glycoprotein.Comparative immunogenicity of subtype a Human Immunodeficiency Virus type 1 envelope exhibiting differential exposure of conserved neutralization epitopesA rev1-vpu polymorphism unique to HIV-1 subtype A and C strains impairs envelope glycoprotein expression from rev-vpu-env cassettes and reduces virion infectivity in pseudotyping assays.Genetic signatures in the envelope glycoproteins of HIV-1 that associate with broadly neutralizing antibodies.Rational antibody-based HIV-1 vaccine design: current approaches and future directionsDesign of lipid nanocapsule delivery vehicles for multivalent display of recombinant Env trimers in HIV vaccinationCross-clade HIV-1 neutralizing antibodies induced with V3-scaffold protein immunogens following priming with gp120 DNA.Partial enzymatic deglycosylation preserves the structure of cleaved recombinant HIV-1 envelope glycoprotein trimers.Stabilized HIV-1 envelope glycoprotein trimers lacking the V1V2 domain, obtained by virus evolution.Structure/Function Studies Involving the V3 Region of the HIV-1 Envelope Delineate Multiple Factors That Affect Neutralization Sensitivity.Recombinant HIV envelope proteins fail to engage germline versions of anti-CD4bs bNAbsComparative Immunogenicity of Evolved V1V2-Deleted HIV-1 Envelope Glycoprotein TrimersAntibody responses elicited in macaques immunized with human immunodeficiency virus type 1 (HIV-1) SF162-derived gp140 envelope immunogens: comparison with those elicited during homologous simian/human immunodeficiency virus SHIVSF162P4 and heteroloAllosteric induction of the CD4-bound conformation of HIV-1 Gp120.Binding interactions between soluble HIV envelope glycoproteins and quaternary-structure-specific monoclonal antibodies PG9 and PG16.Trimeric HIV-1 glycoprotein gp140 immunogens and native HIV-1 envelope glycoproteins display the same closed and open quaternary molecular architecturesStructural and immunogenicity studies of a cleaved, stabilized envelope trimer derived from subtype A HIV-1Bimodal AIDS vaccine approach: induction of cellular as well as humoral immunity can protect from systemic infection.Engineering, expression, purification, and characterization of stable clade A/B recombinant soluble heterotrimeric gp140 proteins.Antigenic and immunogenic study of membrane-proximal external region-grafted gp120 antigens by a DNA prime-protein boost immunization strategyTargeting HIV-1 envelope glycoprotein trimers to B cells by using APRIL improves antibody responses.Optimization of HIV-1 Envelope DNA Vaccine Candidates within Three Different Animal Models, Guinea Pigs, Rabbits and Cynomolgus MacaquesDissecting the neutralizing antibody specificities of broadly neutralizing sera from human immunodeficiency virus type 1-infected donors.Isolation and characterization of monoclonal antibodies elicited by trimeric HIV-1 Env gp140 protein immunogens.A comparative immunogenicity study of HIV-1 virus-like particles bearing various forms of envelope proteins, particles bearing no envelope and soluble monomeric gp120.A Bivalent, Chimeric Rabies Virus Expressing Simian Immunodeficiency Virus Envelope Induces Multifunctional Antibody Responses.Cell surface expression of CCR5 and other host factors influence the inhibition of HIV-1 infection of human lymphocytes by CCR5 ligands.Cross-subtype antibody and cellular immune responses induced by a polyvalent DNA prime-protein boost HIV-1 vaccine in healthy human volunteersAiming to induce broadly reactive neutralizing antibody responses with HIV-1 vaccine candidates.Characterization of neutralizing antibody responses elicited by clade A envelope immunogens derived from early transmitted viruses.Design of an Escherichia coli expressed HIV-1 gp120 fragment immunogen that binds to b12 and induces broad and potent neutralizing antibodies.
P2860
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P2860
Evaluating the immunogenicity of a disulfide-stabilized, cleaved, trimeric form of the envelope glycoprotein complex of human immunodeficiency virus type 1
description
2005 nî lūn-bûn
@nan
2005 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2005 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
name
Evaluating the immunogenicity ...... immunodeficiency virus type 1
@ast
Evaluating the immunogenicity ...... immunodeficiency virus type 1
@en
type
label
Evaluating the immunogenicity ...... immunodeficiency virus type 1
@ast
Evaluating the immunogenicity ...... immunodeficiency virus type 1
@en
prefLabel
Evaluating the immunogenicity ...... immunodeficiency virus type 1
@ast
Evaluating the immunogenicity ...... immunodeficiency virus type 1
@en
P2093
P2860
P1433
P1476
Evaluating the immunogenicity ...... immunodeficiency virus type 1
@en
P2093
Elizabeth Michael
John P Moore
Kelly Barnes
Marc Kirschner
Michael Franti
Norbert Schülke
Paul J Maddon
Rogier W Sanders
Simon Beddows
Thomas Ketas
P2860
P304
P356
10.1128/JVI.79.14.8812-8827.2005
P577
2005-07-01T00:00:00Z