Structure-function analysis of the Z-DNA-binding domain Zalpha of dsRNA adenosine deaminase type I reveals similarity to the (alpha + beta) family of helix-turn-helix proteins
about
Z-DNA-binding proteins can act as potent effectors of gene expression in vivo.The role of binding domains for dsRNA and Z-DNA in the in vivo editing of minimal substrates by ADAR1The solution structure of the Zalpha domain of the human RNA editing enzyme ADAR1 reveals a prepositioned binding surface for Z-DNAA role for Z-DNA binding in vaccinia virus pathogenesisModulation of ADAR1 editing activity by Z-RNA in vitro.The solution structure of the N-terminal domain of E3L shows a tyrosine conformation that may explain its reduced affinity to Z-DNA in vitroThe crystal structure of the second Z-DNA binding domain of human DAI (ZBP1) in complex with Z-DNA reveals an unusual binding mode to Z-DNAAlternate rRNA secondary structures as regulators of translationCrystal Structure of a Poxvirus-Like Zalpha Domain from Cyprinid Herpesvirus 3Structural and functional studies of a large winged Z-DNA-binding domain of Danio rerio protein kinase PKZThe Shwachman-Bodian-Diamond syndrome protein family is involved in RNA metabolism.Editing of messenger RNA precursors and of tRNAs by adenosine to inosine conversion.CRM1 mediates the export of ADAR1 through a nuclear export signal within the Z-DNA binding domain.Elevated activity of the large form of ADAR1 in vivo: very efficient RNA editing occurs in the cytoplasm.Solution structure of the Zbeta domain of human DNA-dependent activator of IFN-regulatory factors and its binding modes to B- and Z-DNAs.The RNA-editing enzyme ADAR1 controls innate immune responses to RNA.Human genomic Z-DNA segments probed by the Z alpha domain of ADAR1.Variola virus E3L Zα domain, but not its Z-DNA binding activity, is required for PKR inhibitionADARs: allies or enemies? The importance of A-to-I RNA editing in human disease: from cancer to HIV-1.The Zα domain of fish PKZ facilitates the B-Z conformational transition of oligonucleotide DNAs with d(GC)(n) inserts.The interaction between Z-DNA and the Zab domain of double-stranded RNA adenosine deaminase characterized using fusion nucleases.Sensing of viral and endogenous RNA by ZBP1/DAI induces necroptosis.Proteins that contain a functional Z-DNA-binding domain localize to cytoplasmic stress granules.A 6 bp Z-DNA hairpin binds two Zα domains from the human RNA editing enzyme ADAR1
P2860
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P2860
Structure-function analysis of the Z-DNA-binding domain Zalpha of dsRNA adenosine deaminase type I reveals similarity to the (alpha + beta) family of helix-turn-helix proteins
description
1999 nî lūn-bûn
@nan
1999 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
1999 թվականի հունվարին հրատարակված գիտական հոդված
@hy
1999年の論文
@ja
1999年論文
@yue
1999年論文
@zh-hant
1999年論文
@zh-hk
1999年論文
@zh-mo
1999年論文
@zh-tw
1999年论文
@wuu
name
Structure-function analysis of ...... y of helix-turn-helix proteins
@ast
Structure-function analysis of ...... y of helix-turn-helix proteins
@en
type
label
Structure-function analysis of ...... y of helix-turn-helix proteins
@ast
Structure-function analysis of ...... y of helix-turn-helix proteins
@en
prefLabel
Structure-function analysis of ...... y of helix-turn-helix proteins
@ast
Structure-function analysis of ...... y of helix-turn-helix proteins
@en
P2093
P2860
P356
P1433
P1476
Structure-function analysis of ...... y of helix-turn-helix proteins
@en
P2093
P2860
P304
P356
10.1093/EMBOJ/18.2.470
P407
P577
1999-01-01T00:00:00Z