Sac1p plays a crucial role in microsomal ATP transport, which is distinct from its function in Golgi phospholipid metabolism.
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The human phosphatidylinositol phosphatase SAC1 interacts with the coatomer I complexThe protein translocation channel mediates glycopeptide export across the endoplasmic reticulum membranePtdIns4 P recognition by Vps74/GOLPH3 links PtdIns 4-kinase signaling to retrograde Golgi traffickingSac1 lipid phosphatase and Stt4 phosphatidylinositol 4-kinase regulate a pool of phosphatidylinositol 4-phosphate that functions in the control of the actin cytoskeleton and vacuole morphology.Pleiotropic alterations in lipid metabolism in yeast sac1 mutants: relationship to "bypass Sec14p" and inositol auxotrophy.Cell growth-dependent coordination of lipid signaling and glycosylation is mediated by interactions between Sac1p and Dpm1p.ATP uptake in the Golgi and extracellular release require Mcd4 protein and the vacuolar H+-ATPase.Retention of the yeast Sac1p phosphatase in the endoplasmic reticulum causes distinct changes in cellular phosphoinositide levels and stimulates microsomal ATP transport.Functional characterization of a mammalian Sac1 and mutants exhibiting substrate-specific defects in phosphoinositide phosphatase activityrSac3, a novel Sac domain phosphoinositide phosphatase, promotes neurite outgrowth in PC12 cellsExpression of yeast lipid phosphatase Sac1p is regulated by phosphatidylinositol-4-phosphateThe Sac domain-containing phosphoinositide phosphatases: structure, function, and diseasePhosphoinositide phosphatases in cell biology and disease.Sac phosphatase domain proteins.Functional studies of the mammalian Sac1 phosphoinositide phosphataseLipid metabolism and regulation of membrane trafficking.The structure of phosphoinositide phosphatases: Insights into substrate specificity and catalysis.Synthesis and function of membrane phosphoinositides in budding yeast, Saccharomyces cerevisiaeThe yeast GRD20 gene is required for protein sorting in the trans-Golgi network/endosomal system and for polarization of the actin cytoskeleton.SAC1 lipid phosphatase and growth control of the secretory pathway.Regulation of Golgi function via phosphoinositide lipids.ATP increases within the lumen of the endoplasmic reticulum upon intracellular Ca2+ release.Growth and metabolic control of lipid signalling at the Golgi.Decreased UDP-GlcNAc levels abrogate proliferation control in EMeg32-deficient cells.Spatial regulation of Golgi phosphatidylinositol-4-phosphate is required for enzyme localization and glycosylation fidelityThree SAC1-like genes show overlapping patterns of expression in Arabidopsis but are remarkably silent during embryo development.Regulation of intracellular phosphatidylinositol-4-phosphate by the Sac1 lipid phosphatase.Identification of a novel adenine nucleotide transporter in the endoplasmic reticulum of Arabidopsis.Identification of an endoplasmic reticulum ATP/ADP transporter.SAC-1 ensures epithelial endocytic recycling by restricting ARF-6 activity.Inactivation of the Phosphoinositide Phosphatases Sac1p and Inp54p Leads to Accumulation of Phosphatidylinositol 4,5-Bisphosphate on Vacuole Membranes and Vacuolar Fusion DefectsAXER is an ATP/ADP exchanger in the membrane of the endoplasmic reticulum
P2860
Q24296999-09183A9D-1E6D-4CB5-B46C-255A122F535BQ27478172-9684A0A0-D2CF-4376-8AA2-B74E59B4859CQ27658740-E342EBC5-1E68-49BC-BA10-093121F3849BQ27930228-BBE37DAD-3CD6-4FBA-BD49-1B18EF3CD32DQ27933594-12571081-D26D-473F-94BC-78802D19DB63Q27934953-17F63AF6-A56B-46AB-A64B-748CE993968DQ27935577-FF693094-7DBA-472F-8EC1-B0E84AA0EF46Q27935801-5F302DCC-1750-48F3-A870-DC95E7B87DAAQ28567201-2143C32F-4D8F-4665-9E25-C230AC510ED7Q28580019-E07EB1C5-0599-47A9-8ABD-AA6BEBCCE7F4Q33316869-26209AC0-DB66-4312-A3FA-327143182BB9Q33649917-7C9A4A2A-E0AF-4756-B11D-BA3603A4C61CQ33862413-568FF09C-CF83-4D8D-86BC-22E257B9C662Q33914389-68140B4E-38A5-44A1-9F77-2E38E84F516AQ33956911-5792B9B3-6033-4825-82BC-6F8CD5D6EACCQ34156587-3C07D28B-84A4-476B-9883-A3257130DF13Q35225936-05A047B2-7EE1-46D3-BE3A-BF938395F80AQ36768641-EDC7F0DC-AB6D-44AF-86F7-1636442B3EA1Q36955558-71D7EC11-BC8C-4046-A16C-D341C63305E1Q37350551-E25C3BDE-539F-4C58-8C64-3960C03D1448Q37512651-C7CB30BD-189B-4375-8372-11BB0D9F5E36Q37533684-9E4B362B-F93C-4A07-8FD1-53D0C3D84C5DQ37977180-D18DDED9-54BB-4A7E-997E-B417CFF136BAQ40370792-A3AEF987-34F7-41F6-B33E-087EC1D26387Q42534155-023A1F73-35B3-42B7-BF77-73F76E86A0BDQ44416345-7DC90DB7-EEB8-4413-AB70-A3E56E0B5C7FQ45212986-4A7FEF82-B881-41AE-A2D0-434A8E5252E7Q46736378-15776525-E2F5-495F-B722-C514039D7270Q46736385-C8FF1771-67A6-4DCC-8B28-C9CDF49F1DCCQ51736955-66EF7820-70F0-466F-8770-FCEBD59DF446Q58480863-1B6EA4A3-4A47-4154-9846-B5F3E0FE0D2DQ58699739-C00B22C9-811F-4F31-8FA4-A2788C384036
P2860
Sac1p plays a crucial role in microsomal ATP transport, which is distinct from its function in Golgi phospholipid metabolism.
description
1999 nî lūn-bûn
@nan
1999 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
1999 թվականի մարտին հրատարակված գիտական հոդված
@hy
1999年の論文
@ja
1999年論文
@yue
1999年論文
@zh-hant
1999年論文
@zh-hk
1999年論文
@zh-mo
1999年論文
@zh-tw
1999年论文
@wuu
name
Sac1p plays a crucial role in ...... Golgi phospholipid metabolism.
@ast
Sac1p plays a crucial role in ...... Golgi phospholipid metabolism.
@en
type
label
Sac1p plays a crucial role in ...... Golgi phospholipid metabolism.
@ast
Sac1p plays a crucial role in ...... Golgi phospholipid metabolism.
@en
prefLabel
Sac1p plays a crucial role in ...... Golgi phospholipid metabolism.
@ast
Sac1p plays a crucial role in ...... Golgi phospholipid metabolism.
@en
P2093
P2860
P356
P1433
P1476
Sac1p plays a crucial role in ...... Golgi phospholipid metabolism.
@en
P2093
B G Kearns
K U Kochendörfer
P Mayinger
V A Bankaitis
P2860
P304
P356
10.1093/EMBOJ/18.6.1506
P407
P577
1999-03-01T00:00:00Z