Fibroblast growth factor receptor-mediated signals contribute to the malignant phenotype of non-small cell lung cancer cells: therapeutic implications and synergism with epidermal growth factor receptor inhibition.
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Recent developments in receptor tyrosine kinases targeted anticancer therapyTargeting angiogenesis in squamous non-small cell lung cancerSystemic and targeted therapies for early-stage lung cancerCharacterizing tyrosine phosphorylation signaling in lung cancer using SH2 profilingMolecular and clinical significance of fibroblast growth factor 2 (FGF2 /bFGF) in malignancies of solid and hematological cancers for personalized therapiesReceptor tyrosine kinases fall into distinct classes based on their inferred signaling networksAcquired nintedanib resistance in FGFR1-driven small cell lung cancer: role of endothelin-A receptor-activated ABCB1 expressionAnticancer activity of methyl-substituted oxaliplatin analogs.Dovitinib and erlotinib in patients with metastatic non-small cell lung cancer: A drug-drug interaction.Rapidly acquired resistance to EGFR tyrosine kinase inhibitors in NSCLC cell lines through de-repression of FGFR2 and FGFR3 expression.Molecular profiles of EGFR, K-ras, c-met, and FGFR in pulmonary pleomorphic carcinoma, a rare lung malignancyCell surface marker profiling of human tracheal basal cells reveals distinct subpopulations, identifies MST1/MSP as a mitogenic signal, and identifies new biomarkers for lung squamous cell carcinomas.EGFR is not a major driver for osteosarcoma cell growth in vitro but contributes to starvation and chemotherapy resistance.Dramatic response to inhaled dobesilate in a patient with lung squamous cell cancer.Aggressiveness of human melanoma xenograft models is promoted by aneuploidy-driven gene expression deregulationFibroblast growth factor receptors as therapeutic targets in human melanoma: synergism with BRAF inhibition.Adding to the mix: fibroblast growth factor and platelet-derived growth factor receptor pathways as targets in non-small cell lung cancerRapid induction of lung adenocarcinoma by fibroblast growth factor 9 signaling through FGF receptor 3.Sestrin-2, a repressor of PDGFRβ signalling, promotes cigarette-smoke-induced pulmonary emphysema in mice and is upregulated in individuals with COPD.FGFR1, 2 and 3 protein overexpression and molecular aberrations of FGFR3 in early stage non-small cell lung cancer.The fibroblast growth factor receptor signaling pathway as a mediator of intrinsic resistance to EGFR-specific tyrosine kinase inhibitors in non-small cell lung cancerMajor vault protein supports glioblastoma survival and migration by upregulating the EGFR/PI3K signalling axisLoss of phosphodiesterase 4D mediates acquired triapine resistance via Epac-Rap1-Integrin signaling.The crosstalk of RAS with the TGF-β family during carcinoma progression and its implications for targeted cancer therapy.Jekyll and Hyde: the role of the microenvironment on the progression of cancer.Targeting fibroblast-growth-factor-receptor-dependent signaling for cancer therapy.Fibroblast growth factors and their receptors in cancer.Angiogenesis, vasculogenic mimicry and vascular invasion in cutaneous malignant melanoma - implications for therapeutic strategies and targeted therapies.Targeting FGFR in Squamous Cell Carcinoma of the Lung.Fibroblast growth factor receptor inhibition is active against mesothelioma and synergizes with radio- and chemotherapy.Fibroblast growth factor receptor 4: a putative key driver for the aggressive phenotype of hepatocellular carcinoma.Canine and human sarcomas exhibit predominant FGFR1 expression and impaired viability after inhibition of signaling.Investigational drugs targeting fibroblast growth factor receptor in the treatment of non-small cell lung cancer.Fibroblast growth factor receptors are components of autocrine signaling networks in head and neck squamous cell carcinoma cells.Combined treatment of curcumin and small molecule inhibitors suppresses proliferation of A549 and H1299 human non-small-cell lung cancer cells.A therapeutic target for smoking-associated lung cancer.The synthetic inhibitor of fibroblast growth factor receptor PD166866 controls negatively the growth of tumor cells in cultureAlternative Splicing of Fibroblast Growth Factor Receptor IgIII Loops in Cancer.Tumor invasion after treatment of glioblastoma with bevacizumab: radiographic and pathologic correlation in humans and mice.Fibroblast growth factor signaling and inhibition in non-small cell lung cancer and their role in squamous cell tumors.
P2860
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P2860
Fibroblast growth factor receptor-mediated signals contribute to the malignant phenotype of non-small cell lung cancer cells: therapeutic implications and synergism with epidermal growth factor receptor inhibition.
description
2008 nî lūn-bûn
@nan
2008 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
name
Fibroblast growth factor recep ...... th factor receptor inhibition.
@ast
Fibroblast growth factor recep ...... th factor receptor inhibition.
@en
type
label
Fibroblast growth factor recep ...... th factor receptor inhibition.
@ast
Fibroblast growth factor recep ...... th factor receptor inhibition.
@en
prefLabel
Fibroblast growth factor recep ...... th factor receptor inhibition.
@ast
Fibroblast growth factor recep ...... th factor receptor inhibition.
@en
P2093
P2860
P1476
Fibroblast growth factor recep ...... th factor receptor inhibition.
@en
P2093
Bettina Grasl-Kraupp
Brigitte Marian
Christine Gauglhofer
Gudrun Sonvilla
Heidelinde Cantonati
Hendrik Fischer
Klaus Holzmann
Leonilla Elbling
Michael Grusch
Michael Micksche
P2860
P304
P356
10.1158/1535-7163.MCT-08-0444
P577
2008-10-01T00:00:00Z