Minor abnormalities of testis development in mice lacking the gene encoding the MAPK signalling component, MAP3K1. - Test2 - elhamkhani - TriplyDB

Minor abnormalities of testis development in mice lacking the gene encoding the MAPK signalling component, MAP3K1.

Minor abnormalities of testis development in mice lacking the gene encoding the MAPK signalling component, MAP3K1.

http://www.wikidata.org/entity/Q33894760

about

The MEKK1 PHD ubiquitinates TAB1 to activate MAPKs in response to cytokines Gene-Environment Interactions Target Mitogen-activated Protein 3 Kinase 1 (MAP3K1) Signaling in Eyelid Morphogenesis MAP3K1 function is essential for cytoarchitecture of the mouse organ of Corti and survival of auditory hair cells.Transgenic expression of Map3k4 rescues T-associated sex reversal (Tas) in mice.Switching on sex: transcriptional regulation of the testis-determining gene Sry A novel mouse Fgfr2 mutant, hobbyhorse (hob), exhibits complete XY gonadal sex reversal.Disorders of sex development: new genes, new concepts.The goya mouse mutant reveals distinct newly identified roles for MAP3K1 in the development and survival of cochlear sensory hair cells.Novel function of LHFPL2 in female and male distal reproductive tract development The molecular and cellular basis of gonadal sex reversal in mice and humans.Mutation analysis of mitogen activated protein kinase 1 gene in Indian cases of 46,XY disorder of sex development.Gene mutations associated with anomalies of human gonad formation.Genetic regulation of mammalian gonad development.Mechanism of Sex Determination in Humans: Insights from Disorders of Sex Development.Mutations in MAP3K1 tilt the balance from SOX9/FGF9 to WNT/β-catenin signaling.The chemokine CXCL12 and its receptor CXCR4 are implicated in human seminoma metastasis.MAP3K1-related gonadal dysgenesis: Six new cases and review of the literature.Genetic Analyses Reveal Functions for MAP2K3 and MAP2K6 in Mouse Testis Determination.MAP3K1: Genomic Alterations in Cancer and Function in Promoting Cell Survival or Apoptosis.Biallelic and monoallelic ESR2 variants associated with 46,XY disorders of sex development.Hormone induced differential transcriptome analysis of Sertoli cells during postnatal maturation of rat testes.Rapidly screening variants of uncertain significance in the MAP3K1 gene for phenotypic effects.A Human Gonadal Cell Model From Induced Pluripotent Stem Cells

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P2860

Minor abnormalities of testis development in mice lacking the gene encoding the MAPK signalling component, MAP3K1.

http://www.wikidata.org/entity/Q33894760

description

2011 nî lūn-bûn

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2011 թուականի Մայիսին հրատարակուած գիտական յօդուած

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2011 թվականի մայիսին հրատարակված գիտական հոդված

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2011年の論文

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2011年論文

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2011年論文

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2011年論文

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2011年論文

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2011年論文

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2011年论文

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Minor abnormalities of testis ...... signalling component, MAP3K1.

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Minor abnormalities of testis ...... signalling component, MAP3K1.

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Minor abnormalities of testis ...... signalling component, MAP3K1.

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Minor abnormalities of testis ...... signalling component, MAP3K1.

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Minor abnormalities of testis ...... signalling component, MAP3K1.

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Minor abnormalities of testis ...... K signalling component, MAP3K1

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Asha Dopplapudi

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Debora Bogani

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Harry Ostrer

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Sara Wells

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P2860

A mutation in the gene encoding steroidogenic factor-1 causes XY sex reversal and adrenal failure in humans

A human homolog of the yeast Ssk2/Ssk22 MAP kinase kinase kinases, MTK1, mediates stress-induced activation of the p38 and JNK pathways

Nonsyndromic Disorders of Testicular Development

Campomelic dysplasia and autosomal sex reversal caused by mutations in an SRY-related gene

Autosomal sex reversal and campomelic dysplasia are caused by mutations in and around the SRY-related gene SOX9

The PGD2 pathway, independently of FGF9, amplifies SOX9 activity in Sertoli cells during male sexual differentiation

Consensus statement on management of intersex disorders. International Consensus Conference on Intersex

Role of MEKK1 in cell survival and activation of JNK and ERK pathways defined by targeted gene disruption

Cloning of a novel mitogen-activated protein kinase kinase kinase, MEKK4, that selectively regulates the c-Jun amino terminal kinase pathway

Sertoli cell differentiation is induced both cell-autonomously and through prostaglandin signaling during mammalian sex determination

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