about
The therapeutic potential of metal-based antimalarial agents: implications for the mechanism of actionHDP-a novel heme detoxification protein from the malaria parasitePhospholipid membrane-mediated hemozoin formation: the effects of physical properties and evidence of membrane surrounding hemozoinPotencies of human immunodeficiency virus protease inhibitors in vitro against Plasmodium falciparum and in vivo against murine malariaArtemisinin-based combination therapies: a vital tool in efforts to eliminate malariaHemozoin: oil versus waterA magneto-optic route toward the in vivo diagnosis of malaria: preliminary results and preclinical trial dataThe relationship of physico-chemical properties and structure to the differential antiplasmodial activity of the cinchona alkaloidsPolymorphism in the Plasmodium falciparum chloroquine-resistance transporter protein links verapamil enhancement of chloroquine sensitivity with the clinical efficacy of amodiaquineThe development of malaria diagnostic techniques: a review of the approaches with focus on dielectrophoretic and magnetophoretic methods.Recent Updates on DTD (D-Tyr-tRNA(Tyr) Deacylase): An Enzyme Essential for Fidelity and Quality of Protein SynthesisBis-methionyl Coordination in the Crystal Structure of the Heme-binding Domain of the Streptococcal Cell Surface Protein ShpStructural Basis for Multimeric Heme Complexation through a Specific Protein-Heme Interaction: THE CASE OF THE THIRD NEAT DOMAIN OF IsdH FROM STAPHYLOCOCCUS AUREUSSelective binding of antimicrobial porphyrins to the heme-receptor IsdH-NEAT3 ofStaphylococcus aureusMutations in the P-Type Cation-Transporter ATPase 4, PfATP4, Mediate Resistance to Both Aminopyrazole and Spiroindolone AntimalarialsPlasmodium falciparum merozoite surface protein 3: oligomerization, self-assembly, and heme complex formationOn the mechanism of chloroquine resistance in Plasmodium falciparumSynthesis of New 4-Aminoquinolines and Evaluation of Their In Vitro Activity against Chloroquine-Sensitive and Chloroquine-Resistant Plasmodium falciparumA novel way to grow hemozoin-like crystals in vitro and its use to screen for hemozoin inhibiting antimalarial compoundsGlutathione transport: a new role for PfCRT in chloroquine resistancePlasmodium falciparum: nitric oxide modulates heme speciation in isolated food vacuolesMalarial hemozoin: from target to toolIdentification of β-hematin inhibitors in a high-throughput screening effort reveals scaffolds with in vitro antimalarial activity.Hemozoin-generated vapor nanobubbles for transdermal reagent- and needle-free detection of malaria.Computational investigation on the photoacoustics of malaria infected red blood cells.The neutral lipid composition present in the digestive vacuole of Plasmodium falciparum concentrates heme and mediates β-hematin formation with an unusually low activation energy.Soft X-ray microscopy analysis of cell volume and hemoglobin content in erythrocytes infected with asexual and sexual stages of Plasmodium falciparumMalaria pigment crystals as magnetic micro-rotors: key for high-sensitivity diagnosis.Whole-cell phase contrast imaging at the nanoscale using Fresnel coherent diffractive imaging tomography.Characterization of the chloroquine resistance transporter homologue in Toxoplasma gondiiHematin polymerization assay as a high-throughput screen for identification of new antimalarial pharmacophores.Characterization of the Alkylation Product of Heme by the Antimalarial Drug Artemisinin We are grateful to the CNRS for financial support, and to the French Ministery of Education for a PhD grant to J.C. Dr. Yannick Coppel (LCC-CNRS) is gratefully aReaction of artemisinin with haemoglobin: implications for antimalarial activity.Resonance Raman spectroscopy in malaria research.Formation of the food vacuole in Plasmodium falciparum: a potential role for the 19 kDa fragment of merozoite surface protein 1 (MSP1(19))Finding crystal structures from few diffraction data by a combination of a random search with genetic algorithms.Synthetic Plasmodium-like hemozoin activates the immune response: a morphology - function studyHemozoin (malarial pigment) directly promotes apoptosis of erythroid precursors.Detection and quantification of early-stage malaria parasites in laboratory infected erythrocytes by attenuated total reflectance infrared spectroscopy and multivariate analysisIncrease on the initial soluble heme levels in acidic conditions is an important mechanism for spontaneous heme crystallization in vitro
P2860
Q20906133-D8B523ED-75E9-4631-875C-9F124C310F38Q21559501-028BDA3A-E684-4CAD-9096-C4B528D3D50EQ21559583-92F86502-0ECA-4A6C-A3D8-5775FEDE1303Q24538763-4BB366B8-77E1-4443-84F2-CE0BFCC0AC44Q24614989-B9126037-49D5-45A7-BE17-9CD70792BE95Q24648954-5AE966F9-4060-4065-ACF7-A4FEBC09F29AQ24650371-EE1E1575-FA3F-4170-B019-B36EBFC36F90Q24801973-137CFE09-9A6D-43BC-9E19-7F15B0487504Q24807027-176A503B-1626-475A-B657-16F39CE34992Q26741056-B5379AB9-03D4-4E7A-9083-F6F6182A8434Q26747250-742B40A3-C4ED-48EC-BC2B-48590446304BQ27648724-FE97760F-6EAC-4324-9A4D-AE7162AF11C5Q27651383-5CEE7C7E-B22E-4EFF-AC29-33C63017D0DEQ27678015-A245BEF1-8910-4D11-9DCA-92AD38A8D0EFQ27861952-26A4CE23-13D1-4BD1-8CB5-96952801991AQ27974527-15B12113-23FB-4024-87A9-9EE04B721FD8Q28476197-D931B476-8D02-4C6D-B87E-0ACEDDEF2EFEQ28550371-FDFB1938-725B-499B-A4EC-6E53F8F2CF5CQ28729074-E03B890E-6C0E-4556-9B04-6BF358E08A9EQ30041670-6C372A2A-4AFE-4E98-8C94-5CFD2AAB20FCQ30044522-DDE4C7E9-B76B-4BBF-B1C9-A4B9C3FE2159Q30410108-10B90968-C015-4D30-978C-963C4D2E535BQ30422848-21545243-5D7A-47B1-BD01-2B054A24502AQ30434561-BE69B015-E5D1-4B69-9E59-BFD7CED50ECCQ30459708-805DA0A8-3C0F-4BBA-9779-5802810ADA2DQ30497572-AE3248CF-52EA-4745-A4B0-11ED5A127F53Q30514012-3D8F8998-8E1F-408C-825B-2884FB9268F8Q30537450-EDA20F6E-08FC-488C-A695-0B7D2F4922EEQ30541817-46E00F68-97E3-4D53-8C9E-A6FCDB7FF443Q30603214-029D6C04-93AA-479C-B96B-43B7010C405DQ30654559-811F4905-5A83-45C6-9BF0-B3FC78199964Q31921497-06E4C411-6B87-49EE-83E8-BD0B1B50E7BFQ33206718-606A02B0-3382-4E4B-92BB-16B13FA323DCQ33262368-922AAA22-C2C5-40EC-BF50-A9FAFA712E25Q33366572-A8992500-0AF3-47D6-A303-3787D85CF930Q33450521-5A108DD8-19FC-4510-B546-C89C9E8A5273Q33501725-8218A807-E78A-4863-A299-5F6A6804F3A5Q33521267-6387EA5A-8533-48F8-8150-60A8C8986CF7Q33583122-3F24392C-3D45-4FD4-81E5-D73F06FB0B40Q33698103-2C47D374-E386-4F79-9B5C-6DF3D0687780
P2860
description
2000 nî lūn-bûn
@nan
2000 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2000 թվականի մարտին հրատարակված գիտական հոդված
@hy
2000年の論文
@ja
2000年論文
@yue
2000年論文
@zh-hant
2000年論文
@zh-hk
2000年論文
@zh-mo
2000年論文
@zh-tw
2000年论文
@wuu
name
The structure of malaria pigment beta-haematin.
@ast
The structure of malaria pigment beta-haematin.
@en
type
label
The structure of malaria pigment beta-haematin.
@ast
The structure of malaria pigment beta-haematin.
@en
prefLabel
The structure of malaria pigment beta-haematin.
@ast
The structure of malaria pigment beta-haematin.
@en
P2093
P356
P1433
P1476
The structure of malaria pigment beta-haematin.
@en
P2093
P2888
P304
P356
10.1038/35005132
P407
P577
2000-03-01T00:00:00Z
P5875
P6179
1025974202