Enantioselective synthesis of alpha-amino nitriles from N-benzhydryl imines and HCN with a chiral bicyclic guanidine as catalyst.
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A chiral analog of the bicyclic guanidine TBD: synthesis, structure and Brønsted base catalysisArginine mimetics using α-guanidino acids: introduction of functional groups and stereochemistry adjacent to recognition guanidiniums in peptidesScaleable catalytic asymmetric Strecker syntheses of unnatural α-amino acidsPhantom ring-closing condensation polymerization: towards antibacterial oligoguanidines.The ever-expanding role of asymmetric covalent organocatalysis in scalable, natural product synthesis.Stereoselective Lewis acid mediated (3+2) cycloadditions of N-H- and N-sulfonylaziridines with heterocumulenes.2-[4-(4,5-Dihydro-1H-pyrrol-2-yl)phen-yl]-4,5-dihydro-1H-imidazole2-(2-Thien-yl)-4,5-dihydro-1H-imidazole.2-(3-Chloro-phen-yl)-4,5-dihydro-1H-imidazole.2-(4-Methoxy-phen-yl)-4,5-dihydro-1H-imidazole2-p-Tolyl-4,5-dihydro-1H-imidazole2-(4,5-Dihydro-1H-imidazol-2-yl)-pyridine.Quantum mechanical investigations of organocatalysis: mechanisms, reactivities, and selectivities.Chlorotrimethylsilane activation of acylcyanamides for the synthesis of mono-N-acylguanidines.Higher-Order Cyclopropenimine Superbases: Direct Neutral Brønsted Base Catalyzed Michael Reactions with α-Aryl Esters.Structure-Activity Relationship Studies of Cyclopropenimines as Enantioselective Brønsted Base Catalysts.Chiral squaramide derivatives are excellent hydrogen bond donor catalysts.Efficient three-component Strecker reaction of aldehydes/ketones via NHC-amidate palladium(II) complex catalysis.Preparation of Mono-Cbz Protected Guanidines.Exploring the potential of diarylacetylenediols as hydrogen bonding catalysts.The upside of downsizing: asymmetric trifunctional organocatalysts as small enzyme mimics for cooperative enhancement of both rate and enantioselectivity with regulation.Asymmetric organocatalysis at the service of medicinal chemistryNew Architectures in Hydrogen Bond CatalysisBifunctional iminophosphorane organocatalysts for enantioselective synthesis: application to the ketimine nitro-Mannich reaction.New hydrogen-bonding organocatalysts: Chiral cyclophosphazanes and phosphorus amides as catalysts for asymmetric Michael additions.Asymmetric catalytic N-phosphonyl imine chemistry: the use of primary free amino acids and Et2AlCN for asymmetric catalytic Strecker reaction.Enantioselective bifunctional iminophosphorane catalyzed sulfa-Michael addition of alkyl thiols to unactivated β-substituted-α,β-unsaturated estersSynthesis of bicyclic guanidines via cascade hydroamination/Michael additions of mono-N-acryloylpropargylguanidines.Asymmetric cyanation of aldehydes, ketones, aldimines, and ketimines catalyzed by a versatile catalyst generated from cinchona alkaloid, achiral substituted 2,2'-biphenol and tetraisopropyl titanate.Direct organo-catalytic asymmetric alpha-amination of aldehydes--a simple approach to optically active alpha-amino aldehydes, alpha-amino alcohols, and alpha-amino acids.A theoretical investigation on the Strecker reaction catalyzed by a Ti(IV)-complex catalyst generated from a cinchona alkaloid, achiral substituted 2,2'-biphenol, and tetraisopropyl titanate.Electron-deficient pyridinium salts/thiourea cooperative catalyzed O-glycosylation via activation of O-glycosyl trichloroacetimidate donors.Highly Stereoselective Strecker Synthesis Induced by a Slight Modification of Benzhydrylamine from Achiral to Chiral.Asymmetric Conjugate Addition of Azide to alpha,beta-Unsaturated Carbonyl Compounds Catalyzed by Simple Peptides This research was supported by the U.S. National Institutes of Health (GM-57595). We are also grateful to the U.S. National Science FounCycloaddition of cyclobutenone and azomethine imine enabled by chiral isothiourea organic catalysts.Organocatalytic dynamic kinetic resolution of azlactones to construct chiral N-acyl amino acid oxime esters.Asymmetric synthesis of 2,3-dihydroquinolin-4-one derivatives catalyzed by a chiral bisguanidium salt.Chiral guanidine-catalyzed asymmetric direct vinylogous Michael reaction of α,β-unsaturated γ-butyrolactams with alkylidene malonates.Computational investigation on the mechanism and stereochemistry of guanidine-catalyzed enantioselective isomerization of 3-alkynoates to allenoates.Guanidine organocatalyst for the asymmetric Mannich-type reaction between α-isothiocyanato imide and sulfonyl imines.
P2860
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P2860
Enantioselective synthesis of alpha-amino nitriles from N-benzhydryl imines and HCN with a chiral bicyclic guanidine as catalyst.
description
1999 nî lūn-bûn
@nan
1999 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
1999 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
1999年の論文
@ja
1999年論文
@yue
1999年論文
@zh-hant
1999年論文
@zh-hk
1999年論文
@zh-mo
1999年論文
@zh-tw
1999年论文
@wuu
name
Enantioselective synthesis of ...... icyclic guanidine as catalyst.
@ast
Enantioselective synthesis of ...... icyclic guanidine as catalyst.
@en
type
label
Enantioselective synthesis of ...... icyclic guanidine as catalyst.
@ast
Enantioselective synthesis of ...... icyclic guanidine as catalyst.
@en
prefLabel
Enantioselective synthesis of ...... icyclic guanidine as catalyst.
@ast
Enantioselective synthesis of ...... icyclic guanidine as catalyst.
@en
P356
P1433
P1476
Enantioselective synthesis of ...... icyclic guanidine as catalyst.
@en
P2093
P304
P356
10.1021/OL990623L
P407
P577
1999-07-01T00:00:00Z