Arf-dependent regulation of Pdgf signaling in perivascular cells in the developing mouse eye.
about
Divorcing ARF and p53: an unsettled caseArf induction by Tgfβ is influenced by Sp1 and C/ebpβ in opposing directionsTransient expression of the Arf tumor suppressor during male germ cell and eye development in Arf-Cre reporter miceLoss of p19(Arf) facilitates the angiogenic switch and tumor initiation in a multi-stage cancer model via p53-dependent and independent mechanisms.Molecular cloning of the human platelet-derived growth factor receptor beta (PDGFR-beta) promoter and drug targeting of the G-quadruplex-forming region to repress PDGFR-beta expressionTgfbeta signaling directly induces Arf promoter remodeling by a mechanism involving Smads 2/3 and p38 MAPK.Platelet-derived growth factor over-expression in retinal progenitors results in abnormal retinal vessel formation.A distant, cis-acting enhancer drives induction of Arf by Tgfβ in the developing eye.Isolation and characterization of mammalian cells expressing the Arf promoter during eye development.Inactivation of the p19(ARF) tumor suppressor affects intestinal epithelial cell proliferation and integrityINK4a deletion results in improved kidney regeneration and decreased capillary rarefaction after ischemia-reperfusion injury.P14ARF inhibits human glioblastoma-induced angiogenesis by upregulating the expression of TIMP3.Negative regulation of initial steps in skeletal myogenesis by mTOR and other kinasesFormation of persistent hyperplastic primary vitreous in ephrin-A5-/- mice.p19Arf represses platelet-derived growth factor receptor β by transcriptional and posttranscriptional mechanisms.Arf tumor suppressor and miR-205 regulate cell adhesion and formation of extraembryonic endoderm from pluripotent stem cellsp19(Arf) limits primary vitreous cell proliferation driven by PDGF-B.ARF suppresses hepatic vascular neoplasia in a carcinogen-exposed murine model.Varied manifestations of persistent hyperplastic primary vitreous with graded somatic mosaic deletion of a single gene.miR-34a is essential for p19(Arf)-driven cell cycle arrest.An endothelial cell genetic screen identifies the GTPase Rem2 as a suppressor of p19ARF expression that promotes endothelial cell proliferation and angiogenesis.p18Ink4c and p53 Act as tumor suppressors in cyclin D1-driven primitive neuroectodermal tumor.Expression of the Arf tumor suppressor gene is controlled by Tgfbeta2 during development.ARF: a versatile DNA damage response ally at the crossroads of development and tumorigenesis.Mice Homozygous for a Deletion in the Glaucoma Susceptibility Locus INK4 Show Increased Vulnerability of Retinal Ganglion Cells to Elevated Intraocular Pressure.
P2860
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P2860
Arf-dependent regulation of Pdgf signaling in perivascular cells in the developing mouse eye.
description
2005 nî lūn-bûn
@nan
2005 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2005 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
name
Arf-dependent regulation of Pd ...... s in the developing mouse eye.
@ast
Arf-dependent regulation of Pd ...... s in the developing mouse eye.
@en
type
label
Arf-dependent regulation of Pd ...... s in the developing mouse eye.
@ast
Arf-dependent regulation of Pd ...... s in the developing mouse eye.
@en
prefLabel
Arf-dependent regulation of Pd ...... s in the developing mouse eye.
@ast
Arf-dependent regulation of Pd ...... s in the developing mouse eye.
@en
P2093
P2860
P356
P1433
P1476
Arf-dependent regulation of Pd ...... s in the developing mouse eye.
@en
P2093
Amy C Martin
David Bertwistle
Frederique Zindy
J Derek Thornton
Jerold E Rehg
Ricardo L A Silva
Stephen X Skapek
P2860
P304
P356
10.1038/SJ.EMBOJ.7600751
P407
P577
2005-07-21T00:00:00Z