Differential requirements for survivin in hematopoietic cell development. - Test2 - elhamkhani - TriplyDB

Differential requirements for survivin in hematopoietic cell development.

Differential requirements for survivin in hematopoietic cell development.

http://www.wikidata.org/entity/Q33913884

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Survivin: a unique target for tumor therapy Survivin - The inconvenient IAP The tumor gene survivin is highly expressed in adult renal tubular cells: implications for a pathophysiological role in the kidney Proteomics of acute myeloid leukaemia: Cytogenetic risk groups differ specifically in their proteome, interactome and post-translational protein modifications.Precancerous stem cells have the potential for both benign and malignant differentiation Molecular profiles of Quadriceps muscle in myostatin-null mice reveal PI3K and apoptotic pathways as myostatin targets.Characterization of the 12C4 survivin monoclonal antibody and insight into the expression of survivin in human adult tissues.Generation of a novel transgenic mouse model for bioluminescent monitoring of survivin gene activity in vivo at various pathophysiological processes: survivin expression overlaps with stem cell markers 1,1-Bis(3'-indolyl)-1-(p-bromophenyl)methane and related compounds repress survivin and decrease gamma-radiation-induced survivin in colon and pancreatic cancer cells Survivin modulates genes with divergent molecular functions and regulates proliferation of hematopoietic stem cells through Evi-1 Targeting survivin in cancer: novel drug development approaches.Role of the Survivin gene in pathophysiology Integration of CNS survival and differentiation by HIF2α.Survivin and IAP proteins in cell-death mechanisms CD34 cells from patients with trisomy 8 myelodysplastic syndrome (MDS) express early apoptotic markers but avoid programmed cell death by up-regulation of antiapoptotic proteins.Influence of survivin-targeted therapy on chemosensitivity in the treatment of acute myeloid leukemia.Requirements for survivin in terminal differentiation of erythroid cells and maintenance of hematopoietic stem and progenitor cells.Tetraploidy/aneuploidy and stem cells in cancer promotion: The role of chromosome passenger proteins.Survivin study: an update of "what is the next wave"?The evolving roles of canonical WNT signaling in stem cells and tumorigenesis: implications in targeted cancer therapies Survivin overexpression alone does not alter megakaryocyte ploidy nor interfere with erythroid/megakaryocytic lineage development in transgenic mice.Up-regulation of survivin during immortalization of human myofibroblasts is linked to repression of tumor suppressor p16(INK4a) protein and confers resistance to oxidative stress.Low FasL levels promote proliferation of human bone marrow-derived mesenchymal stem cells, higher levels inhibit their differentiation into adipocytes.Effects of survivin on angiogenesis in vivo and in vitro.Normal and malignant megakaryopoiesis.Disruption of Survivin in K562 cells elevates telomerase activity and protects cells against apoptosis induced by the Bcr-abl kinase inhibitor STI571.Survivin is not required for the endomitotic cell cycle of megakaryocytes Prolactin levels correlate with abnormal B cell maturation in MRL and MRL/lpr mouse models of systemic lupus erythematosus-like disease Survivin as a preferential target for cancer therapy.Survivin, a key player in cancer progression, increases in obesity and protects adipose tissue stem cells from apoptosis.BIRC5/Survivin as a target for glycolysis inhibition in high-stage neuroblastoma.Differential regulation of the apoptotic machinery during megakaryocyte differentiation and platelet production by inhibitor of apoptosis protein Livin.A novel role for survivin in erythroblast enucleation.The prognostic significance of survivin expression in gallbladder carcinoma.Upregulation of survivin during immortalization of nontransformed human fibroblasts transduced with telomerase reverse transcriptase.Human T-cell lymphotropic virus type 1 infection of CD34+ hematopoietic progenitor cells induces cell cycle arrest by modulation of p21(cip1/waf1) and survivin.Acetylation of EKLF is essential for epigenetic modification and transcriptional activation of the beta-globin locus.Role of tumor suppressor p53 in megakaryopoiesis and platelet function.Survivin: a new player during erythroblast maturation.Survivin expression is associated with lens epithelial cell proliferation and fiber cell differentiation.

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Differential requirements for survivin in hematopoietic cell development.

http://www.wikidata.org/entity/Q33913884

description

2005 nî lūn-bûn

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2005 թուականի Յուլիսին հրատարակուած գիտական յօդուած

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2005 թվականի հուլիսին հրատարակված գիտական հոդված

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2005年の論文

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2005年論文

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2005年論文

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2005年論文

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2005年論文

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2005年論文

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2005年论文

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name

Differential requirements for survivin in hematopoietic cell development.

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Differential requirements for survivin in hematopoietic cell development.

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type

label

Differential requirements for survivin in hematopoietic cell development.

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Differential requirements for survivin in hematopoietic cell development.

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prefLabel

Differential requirements for survivin in hematopoietic cell development.

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Differential requirements for survivin in hematopoietic cell development.

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Proceedings of the National Academy of Sciences of the United States of America

P1476

Differential requirements for survivin in hematopoietic cell development.

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P2093

Amittha Wickrema

http://www.w3.org/2001/XMLSchema#string

Ganesan Keerthivasan

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John D Crispino

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Sandeep Gurbuxani

http://www.w3.org/2001/XMLSchema#string

Yanfei Xu

http://www.w3.org/2001/XMLSchema#string

P2860

Control of apoptosis and mitotic spindle checkpoint by survivin

Survivin and the inner centromere protein INCENP show similar cell-cycle localization and gene knockout phenotype

INCENP is required for proper targeting of Survivin to the centromeres and the anaphase spindle during mitosis

HBXIP functions as a cofactor of survivin in apoptosis suppression

A novel anti-apoptosis gene, survivin, expressed in cancer and lymphoma

Solution structure of human survivin and its binding interface with Smac/Diablo

Direct interaction between survivin and Smac/DIABLO is essential for the anti-apoptotic activity of survivin during taxol-induced apoptosis

Short hairpin RNAs (shRNAs) induce sequence-specific silencing in mammalian cells

Sustained survivin expression from OX40 costimulatory signals drives T cell clonal expansion

Aberrant quantity and localization of Aurora-B/AIM-1 and survivin during megakaryocyte polyploidization and the consequences of Aurora-B/AIM-1-deregulated expression

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10.1073/PNAS.0500303102

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7689700

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16055565

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1183538

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