Lead exposure during synaptogenesis alters vesicular proteins and impairs vesicular release: potential role of NMDA receptor-dependent BDNF signaling
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Gestational lead exposure selectively decreases retinal dopamine amacrine cells and dopamine content in adult miceMechanisms of lead and manganese neurotoxicityIncreased proliferation of late-born retinal progenitor cells by gestational lead exposure delays rod and bipolar cell differentiationAnimal models of gene-environment interaction in schizophrenia: A dimensional perspective.Is lead exposure in early life an environmental risk factor for Schizophrenia? Neurobiological connections and testable hypotheses.The Long and the Short of it: Gene and Environment Interactions During Early Cortical Development and Consequences for Long-Term Neurological Disease.Developmental lead exposure alters synaptogenesis through inhibiting canonical Wnt pathway in vivo and in vitro.Novel dose-dependent alterations in excitatory GABA during embryonic development associated with lead (Pb) neurotoxicity.Early childhood general anaesthesia exposure and neurocognitive development.Lead exposure during synaptogenesis alters NMDA receptor targeting via NMDA receptor inhibitionCytotoxic, genotoxic, and neurotoxic effects of Mg, Pb, and Fe on pheochromocytoma (PC-12) cells.BDNF and Huntingtin protein modifications by manganese: implications for striatal medium spiny neuron pathology in manganese neurotoxicity.Lead induces similar gene expression changes in brains of gestationally exposed adult mice and in neurons differentiated from mouse embryonic stem cells.Presynaptic mechanisms of lead neurotoxicity: effects on vesicular release, vesicle clustering and mitochondria numberEnhanced nitric oxide production during lead (Pb²⁺) exposure recovers protein expression but not presynaptic localization of synaptic proteins in developing hippocampal neurons.Dysregulation of BDNF-TrkB signaling in developing hippocampal neurons by Pb(2+): implications for an environmental basis of neurodevelopmental disordersChronic early life lead (Pb2+) exposure alters presynaptic vesicle pools in hippocampal synapsesIn Vitro Effects of Lead on Gene Expression in Neural Stem Cells and Associations between Up-regulated Genes and Cognitive Scores in Children.Molecular neurobiology of lead (Pb(2+)): effects on synaptic function.Environmental neurotoxicants and developing brain.Adverse outcome pathways: Application to enhance mechanistic understanding of neurotoxicity.From the Cover: 7,8-Dihydroxyflavone Rescues Lead-Induced Impairment of Vesicular Release: A Novel Therapeutic Approach for Lead Intoxicated Children.Developmental Neurotoxicity of Lead.Alterations of Synaptic Proteins in the Hippocampus of Mouse Offspring Induced by Developmental Lead Exposure.Development of the Adverse Outcome Pathway (AOP): Chronic binding of antagonist to N-methyl-d-aspartate receptors (NMDARs) during brain development induces impairment of learning and memory abilities of children.Low-level Gestational Lead Exposure Alters Dendritic Spine Plasticity in the Hippocampus and Reduces Learning and Memory in Rats.Effects of lead exposure on dendrite and spine development in hippocampal dentate gyrus areas of rats.Study of lead-induced neurotoxicity in neural cells differentiated from adipose tissue-derived stem cells.
P2860
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P2860
Lead exposure during synaptogenesis alters vesicular proteins and impairs vesicular release: potential role of NMDA receptor-dependent BDNF signaling
description
2010 nî lūn-bûn
@nan
2010 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Lead exposure during synaptoge ...... eptor-dependent BDNF signaling
@ast
Lead exposure during synaptoge ...... eptor-dependent BDNF signaling
@en
type
label
Lead exposure during synaptoge ...... eptor-dependent BDNF signaling
@ast
Lead exposure during synaptoge ...... eptor-dependent BDNF signaling
@en
prefLabel
Lead exposure during synaptoge ...... eptor-dependent BDNF signaling
@ast
Lead exposure during synaptoge ...... eptor-dependent BDNF signaling
@en
P2093
P2860
P356
P1476
Lead exposure during synaptoge ...... eptor-dependent BDNF signaling
@en
P2093
April P Neal
Kirstie H Stansfield
Paul F Worley
Richard E Thompson
Tomás R Guilarte
P2860
P304
P356
10.1093/TOXSCI/KFQ111
P577
2010-04-07T00:00:00Z