Genome-wide association meta-analysis of human longevity identifies a novel locus conferring survival beyond 90 years of age. - Test2 - elhamkhani - TriplyDB

Genome-wide association meta-analysis of human longevity identifies a novel locus conferring survival beyond 90 years of age.

Genome-wide association meta-analysis of human longevity identifies a novel locus conferring survival beyond 90 years of age.

http://www.wikidata.org/entity/Q33920700

about

Human longevity: Genetics or Lifestyle? It takes two to tango Genome-wide association studies of late-onset cardiovascular disease Decreased epigenetic age of PBMCs from Italian semi-supercentenarians and their offspring Human-specific derived alleles of CD33 and other genes protect against postreproductive cognitive decline Variants near CHRNA3/5 and APOE have age- and sex-related effects on human lifespan.Genetics: Healthy ageing, the genome and the environment.Epigenetics: Linking Nutrition to Molecular Mechanisms in Aging.The Genomic Basis of Postponed Senescence in Drosophila melanogaster.Genetic variants near MLST8 and DHX57 affect the epigenetic age of the cerebellum.GWAS of longevity in CHARGE consortium confirms APOE and FOXO3 candidacy.Genome-Wide Association Study and Linkage Analysis of the Healthy Aging Index.Genome-Wide Scan Informed by Age-Related Disease Identifies Loci for Exceptional Human Longevity Common variants in SIRT1 and human longevity in a Chinese population Genes and life-style factors in BELFAST nonagenarians: Nature, Nurture and Narrative The APP A673T frequency differs between Nordic countries Genetic evidence for common pathways in human age-related diseases Genetic analysis of variation in lifespan using a multiparental advanced intercross Drosophila mapping population.Why genes extending lifespan in model organisms have not been consistently associated with human longevity and what it means to translation research Copy number variation associates with mortality in long-lived individuals: a genome-wide assessment How the effects of aging and stresses of life are integrated in mortality rates: insights for genetic studies of human health and longevity.Increasing Sibling Relative Risk of Survival to Older and Older Ages and the Importance of Precise Definitions of "Aging," "Life Span," and "Longevity".Novel loci and pathways significantly associated with longevity.Human longevity is influenced by many genetic variants: evidence from 75,000 UK Biobank participants Immunochip analysis identifies association of the RAD50/IL13 region with human longevity.A Genetic Network Associated With Stress Resistance, Longevity, and Cancer in Humans.Blood lipids influence DNA methylation in circulating cells.Associations between STR autosomal markers and longevity.Assessment of the contribution of APOE gene variants to metabolic phenotypes associated with familial longevity at middle age.Intakes of Folate and Vitamin B12 and Biomarkers of Status in the Very Old: The Newcastle 85+ Study.Genome sequencing in a case of Niemann-Pick type C Associations of triglyceride levels with longevity and frailty: A Mendelian randomization analysis.Investigation of the 5q33.3 longevity locus and age-related phenotypes Genetics and underlying pathology of dementia.Living long and ageing well: is epigenomics the missing link between nature and nurture?Bayesian association scan reveals loci associated with human lifespan and linked biomarkers.Genetic factors and epigenetic mechanisms of longevity: current perspectives.Replication of Genome-Wide Association Study Findings of Longevity in White, African American, and Hispanic Women: The Women's Health Initiative.Conserved regulators of cognitive aging: From worms to humans.Genomewide Association Scan of a Mortality Associated Endophenotype for a Long and Healthy Life in the Long Life Family Study.Limitations and risks of meta-analyses of longevity studies.

P2860

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P2860

Genome-wide association meta-analysis of human longevity identifies a novel locus conferring survival beyond 90 years of age.

http://www.wikidata.org/entity/Q33920700

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2014 nî lūn-bûn

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2014 թվականի մարտին հրատարակված գիտական հոդված

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2014年の論文

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Human Molecular Genetics

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Amke Caliebe

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Anna M Bennet

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Anne Murphy

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Anton J M de Craen

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Bastiaan T Heijmans

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Bernard Jeune

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Daníel F Guðbjartsson

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David J Stott

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Diana van Heemst

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Doris Lechner

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P2860

Common inherited variation in mitochondrial genes is not enriched for associations with type 2 diabetes or related glycemic traits

Biological, clinical and population relevance of 95 loci for blood lipids

Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk

Genome-wide association identifies nine common variants associated with fasting proinsulin levels and provides new insights into the pathophysiology of type 2 diabetes

Association of FOXO3A variation with human longevity confirmed in German centenarians

Long non-coding RNAs: insights into functions

Unique lipoprotein phenotype and genotype associated with exceptional longevity

Identification of new susceptibility loci for osteoarthritis (arcOGEN): a genome-wide association study

New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk

Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes

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10.1093/HMG/DDU139

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16

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23

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Fernando Rivadeneira

Cornelia M. van Duijn

Jennifer Harrow

Gonneke Willemsen

Jouke-Jan Hottenga

Jeanine Houwing-Duistermaat

André Uitterlinden

Henning Tiemeier

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2014-03-31T00:00:00Z

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24688116

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4103672

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