Nuclear accumulation of stress response mRNAs contributes to the neurodegeneration caused by Fragile X premutation rCGG repeats - Test2 - elhamkhani - TriplyDB

Nuclear accumulation of stress response mRNAs contributes to the neurodegeneration caused by Fragile X premutation rCGG repeats

Nuclear accumulation of stress response mRNAs contributes to the neurodegeneration caused by Fragile X premutation rCGG repeats

http://www.wikidata.org/entity/Q33926845

about

Use of model systems to understand the etiology of fragile X-associated primary ovarian insufficiency (FXPOI)The RNA helicase DDX5/p68 is a key factor promoting c-fos expression at different levels from transcription to mRNA export Fragile X spectrum disorders Fragile X-associated tremor/ataxia syndrome.The multiple molecular facets of fragile X-associated tremor/ataxia syndrome RNA-mediated neurodegeneration in fragile X-associated tremor/ataxia syndrome The unstable repeats--three evolving faces of neurological disease Fragile X-Associated Tremor/Ataxia Syndrome: From Molecular Pathogenesis to Development of Therapeutics.Mapping of gene expression reveals CYP27A1 as a susceptibility gene for sporadic ALS.CGG repeats in RNA modulate expression of TDP-43 in mouse and fly models of fragile X tremor ataxia syndrome The pur protein family: genetic and structural features in development and disease.Structural basis of nucleic-acid recognition and double-strand unwinding by the essential neuronal protein Pur-alpha Molecular Advances Leading to Treatment Implications for Fragile X Premutation Carriers Current research, diagnosis, and treatment of fragile X-associated tremor/ataxia syndrome.Chemical screen reveals small molecules suppressing fragile X premutation rCGG repeat-mediated neurodegeneration in Drosophila.G4-associated human diseases.Current Gaps in Understanding the Molecular Basis of FXTAS Genome-wide alteration of 5-hydroxymethylcytosine in a mouse model of fragile X-associated tremor/ataxia syndrome Advances in clinical and molecular understanding of the FMR1 premutation and fragile X-associated tremor/ataxia syndrome.Drosophila Pur-α binds to trinucleotide-repeat containing cellular RNAs and translocates to the early oocyte.Repeat-associated non-AUG (RAN) translation and other molecular mechanisms in Fragile X Tremor Ataxia Syndrome.Human DNA Helicase B as a Candidate for Unwinding Secondary CGG Repeat Structures at the Fragile X Mental Retardation Gene.Accumulation of poly(A) RNA in nuclear granules enriched in Sam68 in motor neurons from the SMNΔ7 mouse model of SMA.

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Nuclear accumulation of stress response mRNAs contributes to the neurodegeneration caused by Fragile X premutation rCGG repeats

http://www.wikidata.org/entity/Q33926845

description

2011 nî lūn-bûn

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2011 թուականի Յունիսին հրատարակուած գիտական յօդուած

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2011 թվականի հունիսին հրատարակված գիտական հոդված

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2011年の論文

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2011年論文

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2011年論文

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2011年論文

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2011年論文

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2011年論文

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2011年论文

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name

Nuclear accumulation of stress ...... ile X premutation rCGG repeats

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Nuclear accumulation of stress ...... ile X premutation rCGG repeats

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Nuclear accumulation of stress ...... ile X premutation rCGG repeats

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Nuclear accumulation of stress ...... ile X premutation rCGG repeats

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JOURNAL.PGEN.1002102

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Nuclear accumulation of stress ...... ile X premutation rCGG repeats

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Abrar Qurashi

http://www.w3.org/2001/XMLSchema#string

Jian-Ying Zhou

http://www.w3.org/2001/XMLSchema#string

Junmin Peng

http://www.w3.org/2001/XMLSchema#string

Peng Jin

http://www.w3.org/2001/XMLSchema#string

Wendi Li

http://www.w3.org/2001/XMLSchema#string

P2860

The p68 and p72 DEAD box RNA helicases interact with HDAC1 and repress transcription in a promoter-specific manner

The fragile-X premutation: a maturing perspective.

p68 RNA helicase is an essential human splicing factor that acts at the U1 snRNA-5' splice site duplex.

Purification and identification of p68 RNA helicase acting as a transcriptional coactivator specific for the activation function 1 of human estrogen receptor alpha

Cluster analysis and display of genome-wide expression patterns

DAVID: Database for Annotation, Visualization, and Integrated Discovery

The yeast THO complex and mRNA export factors link RNA metabolism with transcription and genome instability.

Absence of Dbp2p alters both nonsense-mediated mRNA decay and rRNA processing.

The FMR1 CGG repeat mouse displays ubiquitin-positive intranuclear neuronal inclusions; implications for the cerebellar tremor/ataxia syndrome

Neuronal morphogenesis is regulated by the interplay between cyclin-dependent kinase 5 and the ubiquitin ligase mind bomb 1

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10.1371/JOURNAL.PGEN.1002102

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