4-Aminoquinolines: novel nociceptin antagonists with analgesic activity.
about
Small-molecule agonists and antagonists of the opioid receptor-like receptor (ORL1, NOP): ligand-based analysis of structural factors influencing intrinsic activity at NOPPharmacological profiles of a novel opioid receptor-like1 (ORL(1)) receptor antagonist, JTC-801Peptide and nonpeptide ligands for the nociceptin/orphanin FQ receptor ORL1: research tools and potential therapeutic agentsNociceptin/orphanin FQ peptide receptor antagonist JTC-801 reverses pain and anxiety symptoms in a rat model of post-traumatic stress disorderStructural requirements of nociceptin antagonist Ac-RYYRIK-NH2 for receptor binding.Modulation of silent and constitutively active nociceptin/orphanin FQ receptors by potent receptor antagonists and Na+ ions in rat sympathetic neurons.Attenuation of neuropathic pain by the nociceptin/orphanin FQ antagonist JTC-801 is mediated by inhibition of nitric oxide production.2-Amino-5-chloro-pyridinium 2-carb-oxy-acetate.Pharmacological profile of nociceptin/orphanin FQ receptors.[Nphe1,Arg14,Lys15]nociceptin-NH2, a novel potent and selective antagonist of the nociceptin/orphanin FQ receptor.Pharmacological profiles of presynaptic nociceptin/orphanin FQ receptors modulating 5-hydroxytryptamine and noradrenaline release in the rat neocortexCrystal structures of 2-benzyl-amino-4-(4-bromo-phen-yl)-6,7,8,9-tetra-hydro-5H-cyclo-hepta-[b]pyridine-3-carbo-nitrile and 2-benzyl-amino-4-(4-chloro-phen-yl)-6,7,8,9-tetra-hydro-5H-cyclo-hepta[b]pyridine-3-carbo-nitrile.2,3-Diamino-pyridinium hydrogen malonate.Nociceptin Opioid Receptor (NOP) as a Therapeutic Target: Progress in Translation from Preclinical Research to Clinical Utility.Identification of an additional supraspinal component to the analgesic mechanism of action of buprenorphine.A novel series of piperidin-4-yl-1,3-dihydroindol-2-ones as agonist and antagonist ligands at the nociceptin receptor.Synthesis, characterization, antimicrobial, DNA cleavage, and in vitro cytotoxic studies of some metal complexes of schiff base ligand derived from thiazole and quinoline moiety.Development of nociceptin receptor (NOP) agonists and antagonists.Recently patented and promising ORL-1 ligands: where have we been and where are we going?One-pot tandem Ugi-4CR/S(N)Ar approach to highly functionalized quino[2,3-b][1,5]benzoxazepines.The design and synthesis of a novel quinolizidine template for potent opioid and opioid receptor-like (ORL1, NOP) receptor ligands.In vitro and ex vivo effects of a selective nociceptin/orphanin FQ (N/OFQ) peptide receptor antagonist, CompB, on specific binding of [3H]N/OFQ and [35S]GTPgammaS in rat brain and spinal cord.Role of nociceptin/orphanin FQ and NOP receptors in the response to acute and repeated restraint stress in rats.Designing bifunctional NOP receptor-mu opioid receptor ligands from NOP receptor-selective scaffolds. Part I.Effects of naloxone benzoylhydrazone on native and recombinant nociceptin/orphanin FQ receptors.Synthesis and anticonvulsant activity of 1-(2-(8-(benzyloxy)quinolin-2-yl)-1-butyrylcyclopropyl)-3-substituted urea derivatives.Pharmacological profile of nociceptin/orphanin FQ receptors regulating 5-hydroxytryptamine release in the mouse neocortex.Synthesis, reactions, and biological activities of some new thieno[3,2-c]quinoline and pyrrolo[3,2-c]quinoline derivatives.Modular Three-Component Synthesis of 4-Aminoquinolines via an Imidoylative Sonogashira/Cyclization Cascade.A Bioluminescent Cell Assay to Quantify Prion Protein Dimerization
P2860
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P2860
4-Aminoquinolines: novel nociceptin antagonists with analgesic activity.
description
2000 nî lūn-bûn
@nan
2000 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2000 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2000年の論文
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2000年学术文章
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2000年学术文章
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2000年学术文章
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name
4-Aminoquinolines: novel nociceptin antagonists with analgesic activity.
@ast
4-Aminoquinolines: novel nociceptin antagonists with analgesic activity.
@en
type
label
4-Aminoquinolines: novel nociceptin antagonists with analgesic activity.
@ast
4-Aminoquinolines: novel nociceptin antagonists with analgesic activity.
@en
prefLabel
4-Aminoquinolines: novel nociceptin antagonists with analgesic activity.
@ast
4-Aminoquinolines: novel nociceptin antagonists with analgesic activity.
@en
P2093
P356
P1476
4-Aminoquinolines: novel nociceptin antagonists with analgesic activity.
@en
P2093
P304
P356
10.1021/JM0002073
P407
P577
2000-11-01T00:00:00Z