Genetically stable and fully effective smallpox vaccine strain constructed from highly attenuated vaccinia LC16m8
about
Frequency of adverse events after vaccination with different vaccinia strainsSmallpox vaccines for biodefense: need and feasibilityThe evolution of poxvirus vaccinesStructural basis for the binding of the neutralizing antibody, 7D11, to the poxvirus L1 proteinModified H5 promoter improves stability of insert genes while maintaining immunogenicity during extended passage of genetically engineered MVA vaccinesAn attenuated LC16m8 smallpox vaccine: analysis of full-genome sequence and induction of immune protection.Combinations of polyclonal or monoclonal antibodies to proteins of the outer membranes of the two infectious forms of vaccinia virus protect mice against a lethal respiratory challengeSafety of attenuated smallpox vaccine LC16m8 in immunodeficient mice.Elicitation of both anti HIV-1 Env humoral and cellular immunities by replicating vaccinia prime Sendai virus boost regimen and boosting by CD40LmLC16m8, a highly attenuated vaccinia virus vaccine lacking expression of the membrane protein B5R, protects monkeys from monkeypoxSmallpox vaccine safety is dependent on T cells and not B cellsEffect of the deletion of genes encoding proteins of the extracellular virion form of vaccinia virus on vaccine immunogenicity and protective effectiveness in the mouse model.MicroRNA regulation of glycoprotein B5R in oncolytic vaccinia virus reduces viral pathogenicity without impairing its antitumor efficacyDevelopment of the small-molecule antiviral ST-246 as a smallpox therapeutic.Vaccinia Virus LC16m8∆ as a Vaccine Vector for Clinical Applications.Serological responses in humans to the smallpox vaccine LC16m8.Identification of hot spots in the variola virus complement inhibitor (SPICE) for human complement regulation.Vaccinia virus vaccines: past, present and future.Comparative evaluation of the immune responses and protection engendered by LC16m8 and Dryvax smallpox vaccines in a mouse model.Immune responses to the smallpox vaccine given in combination with ST-246, a small-molecule inhibitor of poxvirus dissemination.Smallpox vaccines for biodefense.The new ACAM2000 vaccine and other therapies to control orthopoxvirus outbreaks and bioterror attacks.Combined cytolytic effects of a vaccinia virus encoding a single chain trimer of MHC-I with a Tax-epitope and Tax-specific CTLs on HTLV-I-infected cells in a rat model.Defending against smallpox: a focus on vaccines.Characterization of ectromelia virus deficient in EVM036, the homolog of vaccinia virus F13L, and its application for rapid generation of recombinant viruses.Are We Prepared in Case of a Possible Smallpox-Like Disease Emergence?Challenges and Achievements in Prevention and Treatment of Smallpox.40 Years without Smallpox.Construction and characterization of bacterial artificial chromosomes harboring the full-length genome of a highly attenuated vaccinia virus LC16m8.
P2860
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P2860
Genetically stable and fully effective smallpox vaccine strain constructed from highly attenuated vaccinia LC16m8
description
2005 nî lūn-bûn
@nan
2005 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2005 թվականի մարտին հրատարակված գիտական հոդված
@hy
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
name
Genetically stable and fully e ...... hly attenuated vaccinia LC16m8
@ast
Genetically stable and fully e ...... hly attenuated vaccinia LC16m8
@en
type
label
Genetically stable and fully e ...... hly attenuated vaccinia LC16m8
@ast
Genetically stable and fully e ...... hly attenuated vaccinia LC16m8
@en
prefLabel
Genetically stable and fully e ...... hly attenuated vaccinia LC16m8
@ast
Genetically stable and fully e ...... hly attenuated vaccinia LC16m8
@en
P2093
P2860
P356
P1476
Genetically stable and fully e ...... hly attenuated vaccinia LC16m8
@en
P2093
Hisatoshi Shida
Masato Tashiro
Minoru Kidokoro
P2860
P304
P356
10.1073/PNAS.0406671102
P407
P577
2005-03-07T00:00:00Z