Genomic profiling in Down syndrome acute lymphoblastic leukemia identifies histone gene deletions associated with altered methylation profiles
about
Clinical and genetic features of pediatric acute lymphoblastic leukemia in Down syndrome in the Nordic countries.The biology, pathogenesis and clinical aspects of acute lymphoblastic leukemia in children with Down syndrome.Children's Oncology Group's 2013 blueprint for research: acute lymphoblastic leukemia.The intellectual disability of trisomy 21: differences in gene expression in a case series of patients with lower and higher IQ.Conserved and divergent patterns of DNA methylation in higher vertebrates.Distinct DNA methylation patterns of cognitive impairment and trisomy 21 in Down syndrome.Outcome modeling with CRLF2, IKZF1, JAK, and minimal residual disease in pediatric acute lymphoblastic leukemia: a Children's Oncology Group study.Aberrant STAT5 and PI3K/mTOR pathway signaling occurs in human CRLF2-rearranged B-precursor acute lymphoblastic leukemia.Epigenetic landscape correlates with genetic subtype but does not predict outcome in childhood acute lymphoblastic leukemiaAdvances in the Biology of Acute Lymphoblastic Leukemia-From Genomics to the ClinicHigh modal number and triple trisomies are highly correlated favorable factors in childhood B-cell precursor high hyperdiploid acute lymphoblastic leukemia treated according to the NOPHO ALL 1992/2000 protocols.The Role of Histone Protein Modifications and Mutations in Histone Modifiers in Pediatric B-Cell Progenitor Acute Lymphoblastic Leukemia.Micro RNAs and DNA methylation are regulatory players in human cells with altered X chromosome to autosome balance.Stem and progenitor cell dysfunction in human trisomies.Hematopoietic stem cell transplantation for patients with acute lymphoblastic leukemia and Down syndrome.LIN28B is over-expressed in specific subtypes of pediatric leukemia and regulates lncRNA H19.Suppressors and activators of JAK-STAT signaling at diagnosis and relapse of acute lymphoblastic leukemia in Down syndrome.Identify Down syndrome transcriptome associations using integrative analysis of microarray database and correlation-interaction network.Deletions of IKZF1 and SPRED1 are associated with poor prognosis in a population-based series of pediatric B-cell precursor acute lymphoblastic leukemia diagnosed between 1992 and 2011.Gene alterations involving the CRLF2-JAK pathway and recurrent gene deletions in Down syndrome-associated acute lymphoblastic leukemia in Japan.Outcome in children with Down's syndrome and acute lymphoblastic leukemia: role of IKZF1 deletions and CRLF2 aberrations
P2860
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P2860
Genomic profiling in Down syndrome acute lymphoblastic leukemia identifies histone gene deletions associated with altered methylation profiles
description
2011 nî lūn-bûn
@nan
2011 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年学术文章
@wuu
2011年学术文章
@zh-cn
2011年学术文章
@zh-hans
2011年学术文章
@zh-my
2011年学术文章
@zh-sg
2011年學術文章
@yue
name
Genomic profiling in Down synd ...... h altered methylation profiles
@ast
Genomic profiling in Down synd ...... h altered methylation profiles
@en
type
label
Genomic profiling in Down synd ...... h altered methylation profiles
@ast
Genomic profiling in Down synd ...... h altered methylation profiles
@en
prefLabel
Genomic profiling in Down synd ...... h altered methylation profiles
@ast
Genomic profiling in Down synd ...... h altered methylation profiles
@en
P2093
P2860
P356
P1433
P1476
Genomic profiling in Down synd ...... h altered methylation profiles
@en
P2093
A J Carroll
A Tsimelzon
D Bhojwani
D Morrison
H-C Eastwood Leung
P2860
P2888
P304
P356
10.1038/LEU.2011.128
P577
2011-06-07T00:00:00Z
P6179
1048547613